2-Amino-4-chloro-6-picoline
- Product Name
- 2-Amino-4-chloro-6-picoline
- CAS No.
- 36340-61-1
- Chemical Name
- 2-Amino-4-chloro-6-picoline
- Synonyms
- oro-6-picoL;6-AMINO-4-CHLORO-2-PICOLINE;2-Amino-4-chloro-6-picoline;4-chloro-6-Methyl-2-PyridinaMine;2-AMino-4-chloro-6-Methylpyridine;4-Chloro-6-methylpyridin-2-ylamine;2-Pyridinamine, 4-chloro-6-methyl-;2-Amino-4-chloro-6-picoline ISO 9001：2015 REACH
- CBNumber
- CB1947100
- Molecular Formula
- C6H7ClN2
- Formula Weight
- 142.59
- MOL File
- 36340-61-1.mol
2-Amino-4-chloro-6-picoline Property
- Melting point:
- 108-109 °C
- Boiling point:
- 245.1±35.0 °C(Predicted)
- Density
- 1.260±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- solid
- pka
- 5.96±0.35(Predicted)
- color
- Grey
- InChI
- InChI=1S/C6H7ClN2/c1-4-2-5(7)3-6(8)9-4/h2-3H,1H3,(H2,8,9)
- InChIKey
- IKKMKJOVXQEEHS-UHFFFAOYSA-N
- SMILES
- C1(N)=NC(C)=CC(Cl)=C1
- CAS DataBase Reference
- 36340-61-1
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A595890
- Product name
- 2-Amino-4-chloro-6-picoline
- Packaging
- 50mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- NA66773
- Product name
- 2-Amino-4-chloro-6-methylpyridine
- Packaging
- 500g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- 3H30-5-8G
- Product name
- 4-Chloro-6-methylpyridin-2-amine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $119
- Updated
- 2021/12/16
- Product number
- NA66773
- Product name
- 2-Amino-4-chloro-6-methylpyridine
- Packaging
- 1g
- Price
- $150
- Updated
- 2021/12/16
- Product number
- 3H30-5-8G
- Product name
- 4-Chloro-6-methylpyridin-2-amine
- Purity
- 97%
- Packaging
- 5G
- Price
- $791
- Updated
- 2021/12/16
2-Amino-4-chloro-6-picoline Chemical Properties,Usage,Production
Synthesis
823-96-1
116632-24-7
36340-61-1
The general procedure for the synthesis of 2-amino-4-chloro-6-methylpyridine from 2-amino-4,6-dichloropyridine and trimethylcyclotriboroxane is as follows: to a 10% aqueous solution of dioxane (0.1 M) were added sequentially 2-amino-4,6-dichloropyridine (1.0 eq.), trimethylcyclotriboroxane (1.5 eq.), tetrakis(triphenylphosphine)palladium (0.10 eq.) and potassium carbonate (3.0 eq.). The reaction mixture was heated to 120 °C in an oil bath with continuous stirring for 18 hours. Upon completion of the reaction, it was cooled to room temperature (note: not all ingredients were completely consumed). The reaction mixture was extracted with ethyl acetate and the organic phase was dried over anhydrous sodium sulfate and subsequently concentrated under reduced pressure. The crude product was purified by silica gel column chromatography using 5% methanol/dichloromethane as eluent, resulting in an off-white 2-amino-4-chloro-6-methylpyridine solid in 23% yield.LCMS analysis showed a molecular ion peak (m/z) of 143 (MH+) for the target compound with a retention time (Rt) of 1.11 min on the liquid chromatogram.
References
[1] Patent: US2011/195980, 2011, A1. Location in patent: Page/Page column 15
2-Amino-4-chloro-6-picoline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Amino-4-chloro-6-picoline manufacturers
- Product
- 2-Amino-4-chloro-6-picoline 36340-61-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-18
- Product
- 2-Amino-4-chloro-6-picoline 36340-61-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-30
- Product
- 2-Amino-4-chloro-6-picoline 36340-61-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-24