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ChemicalBook > CAS DataBase List > Mildronate dihydrate

Mildronate dihydrate

Appearance
Product Name
Mildronate dihydrate
CAS No.
86426-17-7
Chemical Name
Mildronate dihydrate
Synonyms
Meldonium;Meldonium dihydrate;3-(2,2,2-Trimethylhydrazinium)propionate dihydrate;Mildronate (hydrate);Mildronatedehydrate;Mildronate dihydrate;Miridazine dihydrate;Phosphonate dihydrate;Meldonium dihydrate CRS;Mildronate dihydrate, >=99%
CBNumber
CB21033832
Molecular Formula
C6H14N2O2.2H2O
Formula Weight
182.218
MOL File
86426-17-7.mol
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Mildronate dihydrate Property

Melting point:
85 - 87°C
storage temp. 
2-8°C
solubility 
H2O: >40mg/mL
form 
powder
color 
white to off-white
Stability:
Hygroscopic
InChIKey
JFWLFLLRLZSBRA-UHFFFAOYSA-N
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M5199
Product name
Mildronate dihydrate
Purity
≥98% (HPLC), powder
Packaging
5mg
Price
$117
Updated
2024/03/01
Sigma-Aldrich
Product number
M5199
Product name
Mildronate dihydrate
Purity
≥98% (HPLC), powder
Packaging
25mg
Price
$388
Updated
2024/03/01
Cayman Chemical
Product number
15997
Product name
Mildronate (hydrate)
Purity
≥98%
Packaging
10mg
Price
$34
Updated
2024/03/01
Cayman Chemical
Product number
15997
Product name
Mildronate (hydrate)
Purity
≥98%
Packaging
25mg
Price
$76
Updated
2024/03/01
Sigma-Aldrich
Product number
Y0001670
Product name
Meldonium dihydrate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0001670
Price
$153
Updated
2024/03/01
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Mildronate dihydrate Chemical Properties,Usage,Production

Appearance

white to off-white powder

Description

Mildronate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.Mildronate (40 μM) inhibits the reaction of γ-butyrobetaine hydroxylase with γ-butyrobetaine with Km and Vmax of 36.8 μM and 0.08 nmol/min/mg protein, respectively.

Uses

Meldonium dihydrate has been used as an anti-ischemic agent to evaluate its protective effects on Ischemia-reperfusion (I/R) in chick embryos.

Biochem/physiol Actions

Meldonium is an Inhibitor of γ-butyrobetaine hydroxylase (BBOX) a key enzyme in the synthesis of carnitine.

Mildronate dihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Mildronate dihydrate manufacturers

PNP Biotech Co. Ltd
Product
Meldonium 86426-17-7
Price
US $0.00/kg
Min. Order
25kg
Purity
98%
Supply Ability
Inquiry
Release date
2022-10-19
shandong perfect biotechnology co.ltd
Product
Mildronate 86426-17-7
Price
US $0.00/g
Min. Order
1g
Purity
98% HPLC
Supply Ability
1ks
Release date
2023-08-03
Hebei Xinsheng New Material Technology Co., LTD.
Product
Mildronate 86426-17-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
20tons
Release date
2023-09-13

86426-17-7, Mildronate dihydrateRelated Search:


  • 3-(2,2,2-Trimethylhydrazinium)propionate dihydrate
  • Mildronate dihydrate
  • Hydrazinium, 2-(2-carboxyethyl)-1,1,1-trimethyl-, inner salt
  • Meldonium
  • Mildronate dihydrate, >=99%
  • Mildronate (hydrate)
  • 3-(1,1,1-Trimethylhydrazin-1-ium-2-yl)propanoate dihydrate
  • Meldonium dihydrate
  • Mildronatedehydrate
  • Miridazine dihydrate
  • Meldonium dihydrate CRS
  • Phosphonate dihydrate
  • Mildronate dihydrate USP/EP/BP
  • Meldonium dihydrate (Y0001670)
  • 86426-17-7
  • C6H14N2O22H2O
  • Cardiovascular APIs
  • Inhibitors
  • 86426-17-7