ChemicalBook > CAS DataBase List > Mildronate dihydrate

Mildronate dihydrate

Appearance

Product Name: Mildronate dihydrate
CAS No.: 86426-17-7
Chemical Name: Mildronate dihydrate
Synonyms: Meldonium;Meldonium dihydrate;3-(2,2,2-Trimethylhydrazinium)propionate dihydrate;Mildronate (hydrate);13C,2H3]-Meldonium;Mildronatedehydrate;Mildronate dihydrate;Miridazine dihydrate;Phosphonate dihydrate;Meldonium|||Mildronate
CBNumber: CB21033832
Molecular Formula: C6H14N2O2.2H2O
Formula Weight: 182.218
MOL File: 86426-17-7.mol

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Mildronate dihydrate Property

Melting point:: 85 - 87°C
storage temp.: 2-8°C
solubility: H2O: >40mg/mL
form: powder
color: white to off-white
Water Solubility: H2O: >40mg/mL
Stability:: Hygroscopic
InChI: InChI=1S/C6H14N2O2.2H2O/c1-8(2,3)7-5-4-6(9)10;;/h7H,4-5H2,1-3H3;2*1H2
InChIKey: JFWLFLLRLZSBRA-UHFFFAOYSA-N
SMILES: [N+](C)(C)(C)NCCC([O-])=O.O.O

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M5199
Product name: Mildronate dihydrate
Purity: ≥98% (HPLC), powder
Packaging: 5mg
Price: $113.76
Updated: 2025/07/31

Sigma-Aldrich

Product number: Y0001670
Product name: Meldonium dihydrate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 10 mg
Price: $156
Updated: 2025/07/31

Sigma-Aldrich

Product number: M5199
Product name: Mildronate dihydrate
Purity: ≥98% (HPLC), powder
Packaging: 25mg
Price: $399
Updated: 2025/07/31

Cayman Chemical

Product number: 15997
Product name: Mildronate (hydrate)
Purity: ≥98%
Packaging: 10mg
Price: $34
Updated: 2024/03/01

Cayman Chemical

Product number: 15997
Product name: Mildronate (hydrate)
Purity: ≥98%
Packaging: 25mg
Price: $76
Updated: 2024/03/01

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Mildronate dihydrate Chemical Properties,Usage,Production

Appearance

white to off-white powder

Description

Mildronate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.Mildronate (40 μM) inhibits the reaction of γ-butyrobetaine hydroxylase with γ-butyrobetaine with Km and Vmax of 36.8 μM and 0.08 nmol/min/mg protein, respectively.

Uses

Meldonium dihydrate has been used as an anti-ischemic agent to evaluate its protective effects on Ischemia-reperfusion (I/R) in chick embryos.

Biochem/physiol Actions

Meldonium is an Inhibitor of γ-butyrobetaine hydroxylase (BBOX) a key enzyme in the synthesis of carnitine.

in vivo

Meldonium (50, 100, or 200 mg/kg; once daily for 3 days) dihydrate modestly attenuates hypoxia-induced lung injury in mice^[3].

Mildronate dihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Mildronate dihydrate manufacturers

Shandong Hanjiang Chemical Co., Ltd

Product: Mildronate dihydrate 86426-17-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1T
Release date: 2025-07-01

Wuhan Biocar Pharmacy CO.,Ltd.

Product: Mildronate dihydrate 86426-17-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 800kg
Release date: 2025-03-05

Shandong Xuhuang New material CoLTD

Product: Meldonium 86426-17-7
Price: US $90.00/KG
Min. Order: 1KG
Purity: 99.99%
Supply Ability: 10T
Release date: 2025-02-21

86426-17-7, Mildronate dihydrateRelated Search:

YTTRIUM CHLORIDE HEXAHYDRATE Quercetin dihydrate Ruthenium(III) chloride hydrate Calcium Propionate LACTOSE, MONOHYDRATE Mildronate Isopropyl-α-[2-methylhydrazino]-p-toluamide Ethyl propionate ISOPROPYLHYDRAZINE HYDROCHLORIDE Levofloxacin heMihydrate 1,2-Dimethylhydrazine Dihydrochloride 2,2-Bis(hydroxymethyl)propionic acid Methylhydrazine (2-METHYL-1H-INDOL-3-YL)-OXO-ACETIC ACID ETHYL ESTER FOROXYMITHINE Mildronate dihydrate

3-(2,2,2-Trimethylhydrazinium)propionate dihydrate

Mildronate dihydrate

Hydrazinium, 2-(2-carboxyethyl)-1,1,1-trimethyl-, inner salt

Meldonium

Mildronate dihydrate, >=99%

Mildronate (hydrate)

3-(1,1,1-Trimethylhydrazin-1-ium-2-yl)propanoate dihydrate

Meldonium dihydrate

Mildronatedehydrate

Miridazine dihydrate

Meldonium dihydrate CRS

Phosphonate dihydrate

Mildronate dihydrate USP/EP/BP

Meldonium dihydrate (Y0001670)

13C,2H3]-Meldonium

Meldonium|||Mildronate

Meldonium dihydrate - Bio-X ?

86426-17-7

C6H14N2O22H2O

Cardiovascular APIs

Inhibitors

86426-17-7