Uses
ChemicalBook > CAS DataBase List > ARP100

ARP100

Uses
Product Name
ARP100
CAS No.
704888-90-4
Chemical Name
ARP100
Synonyms
ARP100;ARP 100 ,S9909;MMP-2 Inhibitor III;ARP-100, 10 mM in DMSO;N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)acetamide;N-hydroxy-2-[(4-phenylphenyl)sulfonyl-propan-2-yloxyamino]acetamide;N-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide;2-[((1,1'-Biphenyl)-4-ylsulfonyl)-(1-methylethoxy)amino]-N-hydroxyacetamide;Acetamide, 2-[([1,1'-biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-;metalloproteinase,Inhibitor,Matrix metalloproteinases,selective,matrigel,ARP 100,matrix,invasion,ARP100,anti-invasive,MMP,ARP-100,inhibit
CBNumber
CB21075595
Molecular Formula
C17H20N2O5S
Formula Weight
364.42
MOL File
704888-90-4.mol
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ARP100 Property

storage temp. 
Desiccate at +4°C
solubility 
Soluble at 100mM in DMSO
form 
Solid
color 
Off-white to light yellow
InChI
1S/C17H20N2O5S/c1-13(2)24-19(12-17(20)18-21)25(22,23)16-10-8-15(9-11-16)14-6-4-3-5-7-14/h3-11,13,21H,12H2,1-2H3,(H,18,20)
InChIKey
PHGLPDURIUEELR-UHFFFAOYSA-N
SMILES
[S](=O)(=O)(N(OC(C)C)CC(=O)NO)c1ccc(cc1)c2ccccc2
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Safety

WGK Germany 
WGK 1
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
444288
Product name
MMP-2 Inhibitor III - CAS 704888-90-4 - Calbiochem
Packaging
5mg
Price
$290
Updated
2025/07/31
Cayman Chemical
Product number
13321
Product name
ARP 100
Purity
≥98%
Packaging
1mg
Price
$29
Updated
2024/03/01
Cayman Chemical
Product number
13321
Product name
ARP 100
Purity
≥98%
Packaging
5mg
Price
$104
Updated
2024/03/01
Cayman Chemical
Product number
13321
Product name
ARP 100
Purity
≥98%
Packaging
10mg
Price
$186
Updated
2024/03/01
Tocris
Product number
2621
Product name
ARP 100
Purity
≥99%(HPLC)
Packaging
5
Price
$149
Updated
2021/12/16
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ARP100 Chemical Properties,Usage,Production

Uses

ARP 100 is a potent, dual inhibitor of MMP-12/MMP-13 targets, which are a family of zinc dependent endopeptidases known to play key roles in extracellular matrix (ECM) breakdown disorders, such as the two main forms of arthritis, rheumatoid arthritis (RA) and osteoarthritis (OA).

Uses

A selective inhibitor of MMP-2

Biological Activity

Selective inhibitor of MMP-2 (IC 50 = 12 nM); displays selectivity over MMP-9, MMP-3, MMP-1 and MMP-7 (IC 50 values are 200, 4500, > 50000 and > 50000 nM respectively). Exhibits anti-invasive properties in HT1080 fibrosarcoma cells.

IC 50

MMP-2: 12 nM (IC50); MMP-9: 0.2 μM (IC50); MMP-3: 4.5 μM (IC50); MMP-1: >50 μM (IC50); MMP-7: >50 μM (IC50)

ARP100 Preparation Products And Raw materials

Raw materials

Preparation Products

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ARP100 Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
VDM Biochemicals
Tel
0330-2528181
Fax
0330-2528171
Email
sales@vdmbio.com
Country
United States
ProdList
510
Advantage
64
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2782
Advantage
58
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185 18149758185;
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3505
Advantage
58
Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
40000
Advantage
60
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71615
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8000
Advantage
62
Alabiotech Inc.
Tel
001-619-354-5251
Fax
001-855-855-6087
Email
sales@alabiotech-e.com
Country
United States
ProdList
972
Advantage
60
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9892
Advantage
58

704888-90-4, ARP100Related Search:


  • ARP100
  • N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)acetamide
  • 2-[((1,1'-Biphenyl)-4-ylsulfonyl)-(1-methylethoxy)amino]-N-hydroxyacetamide
  • MMP-2 Inhibitor III
  • N-hydroxy-2-[(4-phenylphenyl)sulfonyl-propan-2-yloxyamino]acetamide
  • Acetamide, 2-[([1,1'-biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-
  • N-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide
  • metalloproteinase,Inhibitor,Matrix metalloproteinases,selective,matrigel,ARP 100,matrix,invasion,ARP100,anti-invasive,MMP,ARP-100,inhibit
  • ARP-100, 10 mM in DMSO
  • ARP 100 ,S9909
  • 704888-90-4