Uses
ChemicalBook > CAS DataBase List > ARP100

ARP100

Uses
Product Name
ARP100
CAS No.
704888-90-4
Chemical Name
ARP100
Synonyms
ARP100;MMP-2 Inhibitor III;ARP-100, 10 mM in DMSO;N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)acetamide;N-hydroxy-2-[(4-phenylphenyl)sulfonyl-propan-2-yloxyamino]acetamide;N-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide;2-[((1,1'-Biphenyl)-4-ylsulfonyl)-(1-methylethoxy)amino]-N-hydroxyacetamide;Acetamide, 2-[([1,1'-biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-;metalloproteinase,Inhibitor,Matrix metalloproteinases,selective,matrigel,ARP 100,matrix,invasion,ARP100,anti-invasive,MMP,ARP-100,inhibit
CBNumber
CB21075595
Molecular Formula
C17H20N2O5S
Formula Weight
364.42
MOL File
704888-90-4.mol
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ARP100 Property

storage temp. 
Desiccate at +4°C
solubility 
Soluble at 100mM in DMSO
form 
Solid
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
444288
Product name
MMP-2 Inhibitor III - CAS 704888-90-4 - Calbiochem
Packaging
5mg
Price
$332
Updated
2024/03/01
Alfa Aesar
Product number
J64151
Product name
ARP 100
Packaging
5mg
Price
$83.9
Updated
2021/12/16
Cayman Chemical
Product number
13321
Product name
ARP 100
Purity
≥98%
Packaging
1mg
Price
$29
Updated
2024/03/01
Cayman Chemical
Product number
13321
Product name
ARP 100
Purity
≥98%
Packaging
5mg
Price
$104
Updated
2024/03/01
Cayman Chemical
Product number
13321
Product name
ARP 100
Purity
≥98%
Packaging
10mg
Price
$186
Updated
2024/03/01
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ARP100 Chemical Properties,Usage,Production

Uses

ARP 100 is a potent, dual inhibitor of MMP-12/MMP-13 targets, which are a family of zinc dependent endopeptidases known to play key roles in extracellular matrix (ECM) breakdown disorders, such as the two main forms of arthritis, rheumatoid arthritis (RA) and osteoarthritis (OA).

Uses

A selective inhibitor of MMP-2

Biological Activity

Selective inhibitor of MMP-2 (IC 50 = 12 nM); displays selectivity over MMP-9, MMP-3, MMP-1 and MMP-7 (IC 50 values are 200, 4500, > 50000 and > 50000 nM respectively). Exhibits anti-invasive properties in HT1080 fibrosarcoma cells.

ARP100 Preparation Products And Raw materials

Raw materials

Preparation Products

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ARP100 Suppliers

China 65 Germany 1 India 1 United Kingdom 1 United States 12 USA 1 Global 81
3B Pharmachem (Wuhan) International Co.,Ltd.
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704888-90-4, ARP100Related Search:

ARP100 (2R)-2-[([1,1μ-Biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-3-methyl-butanamide, (R)-N-Hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide

  • ARP100
  • N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)acetamide
  • 2-[((1,1'-Biphenyl)-4-ylsulfonyl)-(1-methylethoxy)amino]-N-hydroxyacetamide
  • MMP-2 Inhibitor III
  • N-hydroxy-2-[(4-phenylphenyl)sulfonyl-propan-2-yloxyamino]acetamide
  • Acetamide, 2-[([1,1'-biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-
  • N-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide
  • metalloproteinase,Inhibitor,Matrix metalloproteinases,selective,matrigel,ARP 100,matrix,invasion,ARP100,anti-invasive,MMP,ARP-100,inhibit
  • ARP-100, 10 mM in DMSO
  • 704888-90-4