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3-AMino-4-fluorophenylboronic acid

Application
Product Name
3-AMino-4-fluorophenylboronic acid
CAS No.
873566-75-7
Chemical Name
3-AMino-4-fluorophenylboronic acid
Synonyms
5-Borono-2-fluoroaniline;3-amino-4-fluorobacteric acid;3-AMINO-4-FLUOROPHENYLBORONIC ACID;3-Amine-4-fluorophenylboronic acid;3-Amino-4-fluorobenzeneboronic acid;3-Amino-4-fluorophenylboronic acid, 97%,;Boronic acid, B-(3-amino-4-fluorophenyl)-;Boronicacid, (3-amino-4-fluorophenyl)- (9CI);BORONICACID, (3-AMINO-4-FLUOROPHENYL)- (9CI);;(3-aMino-4-fluorophenyl)boronic acid hydrochloride
CBNumber
CB21092954
Molecular Formula
C6H7BFNO2
Formula Weight
154.93
MOL File
873566-75-7.mol
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3-AMino-4-fluorophenylboronic acid Property

Boiling point:
346.0±52.0 °C(Predicted)
Density 
1.34
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
Solid
pka
8.59±0.10(Predicted)
color 
White to off-white
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22
HS Code 
2931900090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
BML00197
Product name
3-Amino-4-fluorophenylboronic acid
Purity
Aldrich
Packaging
1g
Price
$475
Updated
2025/07/31
TRC
Product number
A633240
Product name
3-Amino-4-fluorophenylboronic acid
Packaging
500mg
Price
$85
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA104632
Product name
(3-amino-4-fluorophenyl)boronic Acid
Packaging
100mg
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA104632
Product name
(3-amino-4-fluorophenyl)boronic Acid
Packaging
250mg
Price
$125
Updated
2021/12/16
Apolloscientific
Product number
PC3218
Product name
3-Amino-4-fluorobenzeneboronicacid
Packaging
1g
Price
$182
Updated
2021/12/16
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3-AMino-4-fluorophenylboronic acid Chemical Properties,Usage,Production

Application

3-Amino-4-fluorophenylboronic acid is a boric acid derivative, mainly used as a coupling agent in chemical organic synthesis processes.

Synthesis

352530-22-4

873566-75-7

General procedure for the synthesis of 3-amino-4-fluorophenylboronic acid from 4-fluoro-3-nitrophenylboronic acid: 4-fluoro-3-nitrophenylboronic acid (63 g) was placed in a 500 mL single-necked flask, methanol (100 mL) and palladium-carbon catalyst (6.3 g, 10% loading) were added, followed by sealing the flask with a stopper. After evacuating the system, hydrogen was introduced. The reaction flask was placed in an oil bath at 55 °C with continuous stirring. The hydrogen pressure in the reaction system was maintained by replacing the hydrogen balloon until hydrogen was no longer absorbed. Upon completion of the reaction, the reaction mixture was filtered through a Brinell funnel to remove the palladium-carbon catalyst, and the filtrate was subsequently concentrated to dryness. The concentrate was pulped with n-heptane followed by vacuum drying. The resulting solid was dissolved in methanol (30 mL) and water (150 mL) was added to precipitate out the bulk solid. After removing the methanol and some of the water by distillation, the mixture was cooled to 5 °C. The light gray solid was collected by filtration through a Brinell funnel and dried under vacuum to give 42.6 g of 3-amino-4-fluorophenylboronic acid in 80.7% yield. The structure of the product was confirmed by 1H NMR and the purity was 99.1% as determined by HPLC.

References

[1] Patent: CN103626791, 2016, B. Location in patent: Paragraph 0024; 0025; 0030

3-AMino-4-fluorophenylboronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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3-AMino-4-fluorophenylboronic acid Suppliers

China 98 France 1 Germany 1 India 2 United Kingdom 3 United States 11 Global 116
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
India
ProdList
6905
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from 3-AMino-4-fluorophenylboronic acid manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
3-Amino-4-fluorophenylboronic acid 873566-75-7
Price
US $3.00-9.00/KG
Min. Order
0.1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2025-07-03

873566-75-7, 3-AMino-4-fluorophenylboronic acidRelated Search:

4-Amino-3-fluorophenylboronic acid, pinacol ester 5-AMINO-2-FLUOROPHENYLBORONIC ACID 4-Fluoro-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)aniline 3-Amino-5-fluorophenylboronic acid 4-Amino-2-fluorophenylboronic acid, pinacol ester 2-AMINO-5-FLUOROBENZENEBORONIC ACID 4-Amino-3-fluorophenylboronic acid, hydrochloride 2-Amino-5-fluorophenylboronic acid, HCl 5-Amino-2-fluorophenylboronic acid, HCl 3-Amino-4-fluorophenylboronic acid, pinacol ester 3-AMino-4-fluorophenylboronic acid 3,4-DIFLUORO-5-NITROPHENYLBORONIC ACID 5-AMINO-2,4-DIFLUOROPHENYLBORONIC ACID 3-AMINO-4,5-DIFLUOROPHENYLBORONIC ACID 4-Fluoro-3-nitrophenylboronic acid 2,4-DIFLUORO-5-NITROPHENYLBORONIC ACID (3-CHLORO-4-FLUORO-5-NITRO)BENZENEBORONIC ACID

  • 3-Amino-4-fluorobenzeneboronic acid
  • 5-Borono-2-fluoroaniline
  • Boronicacid, (3-amino-4-fluorophenyl)- (9CI)
  • BORONICACID, (3-AMINO-4-FLUOROPHENYL)- (9CI);
  • (3-aMino-4-fluorophenyl)boronic acid hydrochloride
  • Boronic acid, B-(3-amino-4-fluorophenyl)-
  • 3-Amino-4-fluorophenylboronic acid, 97%,
  • 3-Amine-4-fluorophenylboronic acid
  • 3-AMINO-4-FLUOROPHENYLBORONIC ACID
  • 3-Amino-4-fluorophenylboronic acid(contains varying amounts of Anhydride)
  • 3-amino-4-fluorobacteric acid
  • 873566-75-7