Darodipine

Product Name: Darodipine
CAS No.: 72803-02-2
Chemical Name: Darodipine
Synonyms: PY-108068;PY-108063;PY-108-068;Darodipine;Darodipine(PY-108068);Darodipine, 10 mM in DMSO;diethyl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;PY108068,Ca channels,PY 108068,Calcium Channel,Darodipine,Ca2+ channels,Inhibitor,inhibit;4-(Benzofurazan-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester;3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, 3,5-diethyl ester
CBNumber: CB21118007
Molecular Formula: C19H21N3O5
Formula Weight: 371.39
MOL File: 72803-02-2.mol

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Darodipine Property

Melting point:: 148-151°C
storage temp.: Refrigerator
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form: Solid
color: Pale Yellow to Light Yellow
InChI: InChI=1S/C19H21N3O5/c1-5-25-18(23)14-10(3)20-11(4)15(19(24)26-6-2)16(14)12-8-7-9-13-17(12)22-27-21-13/h7-9,16,20H,5-6H2,1-4H3
InChIKey: QERUYFVNIOLCHV-UHFFFAOYSA-N
SMILES: C1(C)NC(C)=C(C(OCC)=O)C(C2C3C(C=CC=2)=NON=3)C=1C(OCC)=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0005905
Product name: DARODIPINE
Purity: 95.00%
Packaging: 5MG
Price: $504.16
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 56295
Product name: Darodipine
Packaging: 25mg
Price: $650
Updated: 2021/12/16

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Darodipine Chemical Properties,Usage,Production

Uses

Antihypertensive; bronchodilator; vasodilator.

Uses

Darodipine is a calcium channel antagonist.

in vivo

Treatment with darodipine increases the number and the average length of alkaline phosphatase-reactive capillaries and reduces the intercapillary distance and the diameter of cerebral capillaries in old rats. The pericapillary microrenvironment of the Ammon’s horn is the most sensitive to treatment with darodipine^[1]. Darodipine may reduce neuronal cytoskeletal changes occurring in aging and in neurodegenerative disorders. A 6-month treatment (from the 18th to the 24th month of life) with an oral daily dose of 10 mg/kg of darodipine restores in part the expression of 200 kDa-NF subunit immunoreactivity in the cerebellar cortex^[2].

Darodipine Preparation Products And Raw materials

Raw materials

Preparation Products

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Darodipine Suppliers

China 21 United Kingdom 1 United States 4 Global 26

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

MedChemExpress

Tel: --
Fax: --
Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

2A PharmaChem USA

Tel: --
Fax: --
Email: sales@2apharmachem.com
Country: United States
ProdList: 6137
Advantage: 39

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

72803-02-2, DarodipineRelated Search:

Felodipine Paclitaxel 2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLIC ACID 4-METHYL-BENZO(1,2,5)OXADIAZOLE Darodipine

Darodipine

4-(Benzofurazan-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester

PY-108063

PY-108068

PY-108-068

Darodipine(PY-108068)

3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, 3,5-diethyl ester

PY108068,Ca channels,PY 108068,Calcium Channel,Darodipine,Ca2+ channels,Inhibitor,inhibit

diethyl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Darodipine, 10 mM in DMSO

72803-02-2