ChemicalBook > CAS DataBase List > Fantofarone

Fantofarone

Product Name
Fantofarone
CAS No.
114432-13-2
Chemical Name
Fantofarone
Synonyms
CS-2766;SR-33557;Fantofarone;FANTOFARONE;SR-33557;SR33557; 114432-13-2;Parasite,Fantofarone,Ca channels,Calcium Channel,inhibit,SR33557,SR-33557,Inhibitor,Ca2+ channels;2-Isopropyl-1-[[4-[3-[[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino]propoxy]phenyl]sulfonyl]indolizine;3,4-Dimethoxy-N-methyl-N-[3-[4-[[2-(1-methylethyl)-1-indolizinyl]sulfonyl]phenoxy]propyl]benzeneethanamine;Benzeneethanamine, 3,4-dimethoxy-N-methyl-N-[3-[4-[[2-(1-methylethyl)-1-indolizinyl]sulfonyl]phenoxy]propyl]-
CBNumber
CB21118032
Molecular Formula
C31H38N2O5S
Formula Weight
550.71
MOL File
114432-13-2.mol
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Fantofarone Property

Melting point:
82-83°
Density 
dz 1.21 g/cm3
storage temp. 
Store at -20°C
solubility 
DMF: 10 mg/ml; DMSO: 10 mg/ml
form 
A crystalline solid
pka
8.34 ± 0.05(at 25℃)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26381
Product name
Fantofarone
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
26381
Product name
Fantofarone
Packaging
25mg
Price
$745
Updated
2024/03/01
Cayman Chemical
Product number
26381
Product name
Fantofarone
Packaging
5mg
Price
$183
Updated
2024/03/01
Cayman Chemical
Product number
26381
Product name
Fantofarone
Packaging
10mg
Price
$321
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
API0011405
Product name
FANTOFARONE
Purity
95.00%
Packaging
5MG
Price
$496.39
Updated
2021/12/16
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Fantofarone Chemical Properties,Usage,Production

Biological Activity

Fantofarone is a potent antagonist of Calcium Channels.

in vitro

It can be seen that the calcium channel blockers VIZ and Fantofarone (SR) possess a weak intrinsic antimalarial property compared to CQ, and both appear slightly more potent on the CQ-resistant than on the CQ-sensitive parasites.

in vivo

Treatment with isosorbide dinitrate (0.3 mg/kg, i.v.) or Fantofarone (50 mg/kg, i.v.), a reduction is observed in the occurrence and severity of vasospasm, whereas verapamil (0.2 mg/kg, i.v.) is much less effective.

Fantofarone Preparation Products And Raw materials

Raw materials

Preparation Products

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Fantofarone Suppliers

Shanghai Dongyang Biotechnology Co., Ltd.
Tel
0512-0512-13601744364 13601744364
Email
chemsharker@126.com
Country
China
ProdList
879
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4153
Advantage
55
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
Advantage
65
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
ShangHai Biochempartner Co.,Ltd
Tel
17754423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8012
Advantage
62
Shanghai Chaolan Chemical Technology Center
Tel
QQ:65489617 15618227136
Fax
21-5161 9052
Email
info@SuperLan-chem.com
Country
China
ProdList
9748
Advantage
58
Aikon International Limited
Tel
025-66113011 13155353615
Fax
(7)02557626880
Email
qzhang@aikonchem.com
Country
China
ProdList
15396
Advantage
58
Twochem Co.Ltd.
Tel
021-58111628 15800915896
Fax
QQ 3285589261
Country
China
ProdList
1988
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9730
Advantage
58
Taizhou Crene Biotechnology Co. Ltd.
Tel
0576-88813233 13396860566
Email
sales@pharm-intermediates.com
Country
China
ProdList
2013
Advantage
58

114432-13-2, FantofaroneRelated Search:


  • Fantofarone
  • 2-Isopropyl-1-[[4-[3-[[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino]propoxy]phenyl]sulfonyl]indolizine
  • SR-33557
  • 3,4-Dimethoxy-N-methyl-N-[3-[4-[[2-(1-methylethyl)-1-indolizinyl]sulfonyl]phenoxy]propyl]benzeneethanamine
  • FANTOFARONE;SR-33557;SR33557; 114432-13-2
  • CS-2766
  • Benzeneethanamine, 3,4-dimethoxy-N-methyl-N-[3-[4-[[2-(1-methylethyl)-1-indolizinyl]sulfonyl]phenoxy]propyl]-
  • Parasite,Fantofarone,Ca channels,Calcium Channel,inhibit,SR33557,SR-33557,Inhibitor,Ca2+ channels
  • 114432-13-2
  • C31H38N2O5S
  • API