ChemicalBook > CAS DataBase List > Fantofarone
Fantofarone
- Product Name
- Fantofarone
- CAS No.
- 114432-13-2
- Chemical Name
- Fantofarone
- Synonyms
- CS-2766;SR-33557;Fantofarone;FANTOFARONE;SR-33557;SR33557; 114432-13-2;Parasite,Fantofarone,Ca channels,Calcium Channel,inhibit,SR33557,SR-33557,Inhibitor,Ca2+ channels;2-Isopropyl-1-[[4-[3-[[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino]propoxy]phenyl]sulfonyl]indolizine;2-(3,4-dimethoxyphenyl)ethyl](methyl)[3-(4-{[2-(propan-2-yl)indolizin-1-yl]sulfonyl}phenoxy)propyl]amine;3,4-Dimethoxy-N-methyl-N-[3-[4-[[2-(1-methylethyl)-1-indolizinyl]sulfonyl]phenoxy]propyl]benzeneethanamine;Benzeneethanamine, 3,4-dimethoxy-N-methyl-N-[3-[4-[[2-(1-methylethyl)-1-indolizinyl]sulfonyl]phenoxy]propyl]-
- CBNumber
- CB21118032
- Molecular Formula
- C31H38N2O5S
- Formula Weight
- 550.71
- MOL File
- 114432-13-2.mol
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Fantofarone Property
- Melting point:
- 82-83°
- Density
- dz 1.21 g/cm3
- storage temp.
- Store at -20°C
- solubility
- DMF: 10 mg/ml; DMSO: 10 mg/ml
- form
- A crystalline solid
- pka
- 8.34 ± 0.05(at 25℃)
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 26381
- Product name
- Fantofarone
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 26381
- Product name
- Fantofarone
- Packaging
- 25mg
- Price
- $745
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 26381
- Product name
- Fantofarone
- Packaging
- 5mg
- Price
- $183
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 26381
- Product name
- Fantofarone
- Packaging
- 10mg
- Price
- $321
- Updated
- 2024/03/01
ChemScene
- Product number
- CS-0025047
- Product name
- Fantofarone
- Purity
- 98.56%
- Packaging
- 5mg
- Price
- $90
- Updated
- 2021/12/16
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Fantofarone Chemical Properties,Usage,Production
Biological Activity
Fantofarone is a potent antagonist of Calcium Channels.
in vitro
It can be seen that the calcium channel blockers VIZ and Fantofarone (SR) possess a weak intrinsic antimalarial property compared to CQ, and both appear slightly more potent on the CQ-resistant than on the CQ-sensitive parasites.
in vivo
Treatment with isosorbide dinitrate (0.3 mg/kg, i.v.) or Fantofarone (50 mg/kg, i.v.), a reduction is observed in the occurrence and severity of vasospasm, whereas verapamil (0.2 mg/kg, i.v.) is much less effective.
Fantofarone Preparation Products And Raw materials
Raw materials
Preparation Products
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