ChemicalBook > CAS DataBase List > (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide

Product Name
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
CAS No.
135729-78-1
Chemical Name
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
Synonyms
Palonosetron Impurity 3;Palonosetron Impurity 27;Palonosetron Impurity 20;Palonosetron Impurity 1;Palonosetron Impurity 25;Palonosetron Intermediate;(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetra;(S)-N-(Quinuclidin-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxaMide;(S)-N-1-azabicyclo[2.2.0]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide;N-(1-azabicyclo[2.2.2]octan-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide
CBNumber
CB21135547
Molecular Formula
C18H24N2O
Formula Weight
284.4
MOL File
135729-78-1.mol
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(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Property

Melting point:
157-159oC
Boiling point:
439.2±45.0 °C(Predicted)
Density 
1.17
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
14.75±0.20(Predicted)
color 
White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A795320
Product name
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
Packaging
1g
Price
$910
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
63045
Product name
N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
Packaging
250mg
Price
$1250
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0372970
Product name
5,6,7,8-TETRAHYDRO-NAPHTHALENE-1-CARBOXYLIC ACID (1-AZA-BICYCLO[2.2.2]OCT-3-YL)-AMIDE
Purity
95.00%
Packaging
5MG
Price
$504.97
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
63045
Product name
N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
Packaging
25mg
Price
$650
Updated
2021/12/16
Crysdot
Product number
CD11279770
Product name
(S)-N-(Quinuclidin-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide
Purity
95+%
Packaging
1g
Price
$683
Updated
2021/12/16
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(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Chemical Properties,Usage,Production

Uses

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide is an impurity in the synthesis of Palonosetron HCl (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Chemsky(shanghai)International Co.,Ltd.
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021-50135380
Email
shchemsky@sina.com
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China
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32321
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S.Z. PhyStandard Bio-Tech. Co., Ltd.
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0755-4000505016 13380397412
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0755 28094224
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3001272453@qq.com
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China
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SynAsst Chemical.
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021-35122006
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China
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Quality Control Solutions Ltd.
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0755-66853366 13670046396
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0755-28363542
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orders@qcsrm.com
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Shandong Boluoda Biological Technology Co., Ltd.
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0531-68651977
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China
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Nanjing XiZe Biotechnology CO., Ltd.
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025-66023220 15250997978
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025-58362220
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1511893459@qq.com
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China
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Amadis Chemical Company Limited
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571-89925085
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0086-571-89925065
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sales@amadischem.com
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China
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Zhengzhou Huiju Chemical Co., Ltd.
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0371-55900031 18137872243
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3927209986@qq.com
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China
ProdList
10000
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Shenzhen SUNGENING Bio-Medical Co., Ltd.
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0755-28967200 13631290199
Fax
0755-28967200
Email
wxf@sungening.com
Country
China
ProdList
9630
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View Lastest Price from (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide manufacturers

Career Henan Chemical Co
Product
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide 135729-78-1
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2020-02-20
Career Henan Chemical Co
Product
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide 135729-78-1
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200kgs
Release date
2020-01-28

135729-78-1, (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamideRelated Search:


  • (S)-N-1-azabicyclo[2.2.0]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
  • (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
  • Palonosetron Impurity 20
  • Palonosetron Impurity 27
  • N-(1-azabicyclo[2.2.2]octan-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide
  • Palonosetron Impurity 25
  • Palonosetron Impurity 1
  • (S)-N-(Quinuclidin-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxaMide
  • N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxaMide
  • N-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl] 5,6,7,8-tetrahydronaphthalene-1-carboxamide
  • Palonosetron Impurity 3
  • Palonosetron Intermediate
  • 1-Naphthalenecarboxamide, N-(3S)-1-azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-
  • (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetra
  • 135729-78-1
  • Intermediate of palonosetron hcl