1H-Pyrrole-2-carboxamide,1-amino-(9CI)
- Product Name
- 1H-Pyrrole-2-carboxamide,1-amino-(9CI)
- CAS No.
- 159326-69-9
- Chemical Name
- 1H-Pyrrole-2-carboxamide,1-amino-(9CI)
- Synonyms
- 1-aminopyrrole-2-carboxamide;1-AMINO-1H-PYRROLE-2-CARBOXAMIDE;1H-Pyrrole-2-carboxamide, 1-amino-;1H-Pyrrole-2-carboxamide,1-amino-(9CI);1-AMino-1H-pyrrole-2-carboxylic acid aMide
- CBNumber
- CB21285950
- Molecular Formula
- C5H7N3O
- Formula Weight
- 125.13
- MOL File
- 159326-69-9.mol
1H-Pyrrole-2-carboxamide,1-amino-(9CI) Property
- Boiling point:
- 425.9±37.0 °C(Predicted)
- Density
- 1.45±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 16.23±0.50(Predicted)
- Appearance
- Off-white to light yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- A617283
- Product name
- 1-Amino-1h-pyrrole-2-carboxamide
- Packaging
- 500mg
- Price
- $515
- Updated
- 2021/12/16
- Product number
- 070161
- Product name
- 1-Amino-1H-pyrrole-2-carboxamide
- Purity
- 96%
- Packaging
- 500mg
- Price
- $530
- Updated
- 2021/12/16
- Product number
- 070161
- Product name
- 1-Amino-1H-pyrrole-2-carboxamide
- Purity
- 96%
- Packaging
- 1g
- Price
- $822
- Updated
- 2021/12/16
- Product number
- CHM0093595
- Product name
- 1-AMINO-1H-PYRROLE-2-CARBOXAMIDE
- Purity
- 95.00%
- Packaging
- 500MG
- Price
- $1159.62
- Updated
- 2021/12/16
- Product number
- CHM0093595
- Product name
- 1-AMINO-1H-PYRROLE-2-CARBOXAMIDE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1480.71
- Updated
- 2021/12/16
1H-Pyrrole-2-carboxamide,1-amino-(9CI) Chemical Properties,Usage,Production
Synthesis
159326-66-6
159326-69-9
1. 1-Amino-1H-pyrrole-2-carbonitrile (18.00 g, 0.17 mol) was dissolved in water (90 mL) at 0 °C. 2. KOH (47.14 g, 0.84 mol) was slowly added to the above solution. 3. The reaction mixture was stirred at room temperature overnight. 4. The reaction mixture was cooled to -15 °C and stirring was continued for 2 hours. 5. The reaction mixture was filtered and the filter cake was retained. 6. The filtrate was extracted using a solvent mixture of DCM and MeOH (10:1, 200 mL x 10, v/v). 7. The organic phases were combined, dried with anhydrous Na2SO4, filtered and concentrated in vacuum. 8. The concentrated residue was combined with the filter cake retained in step 5. 9. The combined products were purified by silica gel column chromatography (eluent MeOH/DCM, 1:10, v/v) to afford 1-amino-1H-pyrrole-2-carboxamide as a yellow solid (13.12 g, 62% yield). MS (ESI, cationic) m/z: 126.1 [M + H]+. NMR (600 MHz, DMSO-d6) data not provided.
References
[1] Patent: WO2006/35061, 2006, A1. Location in patent: Page/Page column 50; 51
[2] Patent: WO2016/190847, 2016, A1. Location in patent: Paragraph 0341
[3] Patent: CN104974163, 2017, B. Location in patent: Paragraph 0514; 0515; 0516; 0517
[4] Journal of Heterocyclic Chemistry, 1994, vol. 31, # 4, p. 781 - 786
[5] Patent: CN104876935, 2017, B. Location in patent: Paragraph 0066; 0069; 0070
1H-Pyrrole-2-carboxamide,1-amino-(9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1H-Pyrrole-2-carboxamide,1-amino-(9CI) manufacturers
- Product
- 1H-Pyrrole-2-carboxamide,1-amino-(9CI) 159326-69-9
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100g , 1kg, 5kg , 50kg
- Release date
- 2020-01-07