PYRROLO[2,1-F][1,2,4]TRIAZINE-2,4-DIONE
- Product Name
- PYRROLO[2,1-F][1,2,4]TRIAZINE-2,4-DIONE
- CAS No.
- 918538-04-2
- Chemical Name
- PYRROLO[2,1-F][1,2,4]TRIAZINE-2,4-DIONE
- Synonyms
- Pyrrolo[2,1-f][1,2,4]tria...;pyrrolo[2,1-f][1,2,4]triazine-2,4-diol;PYRROLO[2,1-F][1,2,4]TRIAZINE-2,4-DIONE;Pyrrolo[2,1-f][1,2,4]triazine-2,4(1H,3H);1H-pyrrolo[2,1-f][1,2,4]triazine-2,4-dione;Pyrrolo[2,1-f][1,2,4]triazine-2,4(1H,3H)-dione;pyrrolo[1,2-f][1,2,4]triazine-2,4(1H,3H)-dione;PYRROLO[1,2-D][1,2,4]TRIAZINE-2,4(1H,3H)-DIONE;Pyrrolo[2,1-f][1,2,4]triazine-2,4(1H,3H)-dione (96%)
- CBNumber
- CB11519528
- Molecular Formula
- C6H5N3O2
- Formula Weight
- 151.12
- MOL File
- 918538-04-2.mol
PYRROLO[2,1-F][1,2,4]TRIAZINE-2,4-DIONE Property
- Density
- 1.74±0.1 g/cm3 (20 ºC 760 Torr)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 4.92±0.20(Predicted)
- Appearance
- brown solid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- P998753
- Product name
- Pyrrolo[2,1-f][1,2,4]triazine-2,4(1H,3H)-dione
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 4H53-1-25
- Product name
- 1H,2H,3H,4H-Pyrrolo[2,1-f][1,2,4]triazine-2,4-dione
- Purity
- 96%
- Packaging
- 250mg
- Price
- $149
- Updated
- 2021/12/16
- Product number
- OR903929
- Product name
- Pyrrolo[2,1-f][1,2,4]triazine-2,4(1H,3H)-dione
- Purity
- 95%
- Packaging
- 250mg
- Price
- $182
- Updated
- 2021/12/16
- Product number
- OR903929
- Product name
- Pyrrolo[2,1-f][1,2,4]triazine-2,4(1H,3H)-dione
- Purity
- 95%
- Packaging
- 1g
- Price
- $377
- Updated
- 2021/12/16
- Product number
- 4H53-1-25
- Product name
- 1H,2H,3H,4H-Pyrrolo[2,1-f][1,2,4]triazine-2,4-dione
- Purity
- 96%
- Packaging
- 1g
- Price
- $490
- Updated
- 2021/12/16
PYRROLO[2,1-F][1,2,4]TRIAZINE-2,4-DIONE Chemical Properties,Usage,Production
Synthesis
541-41-3
159326-69-9
918538-04-2
(Step 13) Synthesis of pyrrolo[2,1-f][1,2,4]triazine-2,4(1H,3H)-dione: [0342] 1-Amino-1H-pyrrole-2-carboxamide (14.00 g, 0.11 mol) and pyridine (9.90 mL, 0.12 mol) were suspended in anhydrous 1,4-dioxane (120 mL), followed by addition of ethyl chloroformate ( 11.70 mL, 0.12 mol). The reaction mixture was stirred under reflux conditions for 1 h and then concentrated under vacuum. The residue was continued to stir at 155 °C for 17 h. After cooling to room temperature, the mixture was diluted with methanol (50 mL). The resulting mixture was stirred at -15 °C for 2 h. The mixture was filtered, the solid product was collected and dried overnight at 60 °C through a vacuum desiccator to afford gray solid pyrrolo[2,1-f][1,2,4]triazine-2,4(1H,3H)-dione (12.70 g, 75% yield). Mass spectrum (ESI, cation mode) m/z: 152.2 [M + H]+; 1H NMR (400 MHz, DMSO-d6): δ (ppm) 12.96 (s, 1H), 11.7 (s, 1H), 7.13 (m, 1H), 6.75 (dd, J = 4.4, 1.6 Hz, 1H), 6.34 (dd, J = 4.3, 2.6 Hz, 1H).
References
[1] Patent: WO2016/190847, 2016, A1. Location in patent: Paragraph 0342
[2] Patent: CN104974163, 2017, B. Location in patent: Paragraph 0518; 0519; 0520; 0521
[3] Patent: WO2017/219800, 2017, A1. Location in patent: Paragraph 0082; 0083
[4] Patent: US2007/4731, 2007, A1. Location in patent: Page/Page column 15
PYRROLO[2,1-F][1,2,4]TRIAZINE-2,4-DIONE Preparation Products And Raw materials
Raw materials
Preparation Products
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