ChemicalBook > CAS DataBase List > 11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine
11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine
- Product Name
- 11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine
- CAS No.
- 1977-07-7
- Chemical Name
- 11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine
- Synonyms
- Dechloroclozapine;Dopamine serotonin antagonist-1;11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine;11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine;5H-Dibenzo[b,e][1,4]diazepine, 11-(4-methyl-1-piperazinyl)-;inhibit,Inhibitor,Muscarinic acetylcholine receptor,hM4Di,Deschloroclozapine,hM3Dq,muscarinic-based,mAChR,DREADDs;11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepineQ: What is 11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine Q: What is the CAS Number of 11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
- CBNumber
- CB21316359
- Molecular Formula
- C18H20N4
- Formula Weight
- 292.38
- MOL File
- 1977-07-7.mol
More
Less
11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine Property
- Boiling point:
- 457.5±55.0 °C(Predicted)
- Density
- 1.22±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO : ≥ 83.3 mg/mL (284.90 mM)
- pka
- 7.82±0.20(Predicted)
- form
- solid
- color
- Yellow
More
Less
N-Bromosuccinimide Price
ChemScene
- Product number
- CS-M3647
- Product name
- Deschloroclozapine
- Purity
- 99.79%
- Packaging
- 10mg
- Price
- $100
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-M3647
- Product name
- Deschloroclozapine
- Purity
- 99.79%
- Packaging
- 50mg
- Price
- $350
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0997406
- Product name
- 11-(4-METHYL-1-PIPERAZINYL)-5H-DIBENZO(B,E)(1,4)DIAZEPINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.91
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-M3647
- Product name
- Deschloroclozapine
- Purity
- 99.79%
- Packaging
- 100mg
- Price
- $550
- Updated
- 2021/12/16
Alichem
- Product number
- 1977077
- Product name
- 11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
- Packaging
- 100mg
- Price
- $780
- Updated
- 2021/12/16
More
Less
11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine Chemical Properties,Usage,Production
Biological Activity
Deschloroclozapine is a potent, high-affinity, selective, metabolically stable agonist of muscarinic-based DREADDs.
in vitro
Deschloroclozapine has greater potencies for DREADDs than previous agonists in vitro. Deschloroclozapine is a potent agonist for hM 3 Dq with an EC 50 =0.13 nM. Deschloroclozapine is also a potent agonist for hM 4 Di with an EC 50 =0.081 nM.
Deschloroclozapine is a potent and selective agonist for hM 3 Dq and hM 4 Di, it does not display significant agonistic activity for any of the 318 tests wild-type GPCRs at <10 nM.
b>
target
Ki: 6.3 nM (hM 3 Dq), 4.2 nM (hM 4 Di)
storage
Room temperature
11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine Suppliers
- Tel
- --
- Fax
- --
- mktg@pharmaffiliates.com
- Country
- India
- ProdList
- 6739
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
1977-07-7, 11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepineRelated Search:
Lasmiditan Impurity 7
Lasmiditan Impurity 3
LasMiditan
1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole
(1-methylpiperidin-4-yl)(pyridin-2-yl)methanone
(6-aMinopyridin-2-yl)(1-Methylpiperidin-4-yl)Methanone
Lasmiditan Impurity 5
Diacetonefructose
Lasmiditan Impurity 6
(1S,3R,4S)-4-(2-((5-chloropyridin-
2-yl)amino)-2-oxoacetamido)-3-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexane-1-carboxylic acid
Lasmiditan Impurity 1