uvarigrin

Product Name: uvarigrin
CAS No.: 200563-11-7
Chemical Name: uvarigrin
Synonyms: uvarigrin;2(5H)-Furanone, 3-[(13S,15R)-13,15-dihydroxy-15-[(2R,5R)-tetrahydro-5-[(1R)-1-hydroxytridecyl]-2-furanyl]pentadecyl]-5-methyl-, (5S)-
CBNumber: CB21317073
Molecular Formula: C37H68O6
Formula Weight: 608.93
MOL File: 200563-11-7.mol

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uvarigrin Property

Boiling point:: 741.3±35.0 °C(Predicted)
Density: 1.008±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 14.20±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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uvarigrin Chemical Properties,Usage,Production

Uses

Uvarigrin, isolated from the roots of Uvaria calamistrata, induces tumor multidrug resistance cell apoptosis and triggers Caspase-9 activation[1][2].

References

[1] Zhou GX, et al. Calamistrins A and B, two new cytotoxic monotetrahydrofuran annonaceous acetogenins from Uvaria calamistrata. J Nat Prod. 1999 Feb;62(2):261-4. DOI:10.1021/np980334q
[2] Li YF, et al. Induction of apoptosis of tumor multidrug resistance cell by uvarigrin and its mechanism. Yao Xue Xue Bao. 2006 Mar;41(3):252-6. PMID:16758998

uvarigrin Preparation Products And Raw materials

Raw materials

Preparation Products

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uvarigrin

2(5H)-Furanone, 3-[(13S,15R)-13,15-dihydroxy-15-[(2R,5R)-tetrahydro-5-[(1R)-1-hydroxytridecyl]-2-furanyl]pentadecyl]-5-methyl-, (5S)-

200563-11-7

C37H68O6