angoline

Product Name: angoline
CAS No.: 21080-31-9
Chemical Name: angoline
Synonyms: angoline;Angoline, 10 mM in DMSO;6-Methoxydihydrocheleryth;6-Methoxyldihydrochelerythrine;12,13-Dihydro-1,2,13-trimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridine;[1,3]Benzodioxolo[5,6-c]phenanthridine, 12,13-dihydro-1,2,13-trimethoxy-12-methyl-;phosphorylation,proliferation,STAT3,anticancer,inhibit,Angoline,Inhibitor,STAT,IL-6;1,2,13-Trimethoxy-12-methyl-12,13-dihydro-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridine;1,2,13-Trimethoxy-12-methyl-12,13-dihydro-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridine
CBNumber: CB21332988
Molecular Formula: C22H21NO5
Formula Weight: 379.41
MOL File: 21080-31-9.mol

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angoline Property

storage temp.: 4°C, protect from light
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0135179
Product name: Angoline
Purity: 99.67%
Packaging: 5mg
Price: $180
Updated: 2021/12/16

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angoline Chemical Properties,Usage,Production

Description

The empirical formula of this alkaloid should read C21 H21 NO5

Uses

Angoline is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11.56 μM. Angoline inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation[1].

Definition

ChEBI: Angoline is a benzophenanthridine alkaloid.

References

[1] Jiawei Liu, et al. Angoline: a selective IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum. Phytomedicine. Jul-Aug 2014;21(8-9):1088-91. DOI:10.1016/j.phymed.2014.04.001

angoline Preparation Products And Raw materials

Raw materials

Preparation Products

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angoline Suppliers

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21080-31-9, angolineRelated Search:

Sophocarpine 6-Methoxydihydrosanguinarine ALLOCRYPTOPINE DIHYDROSANGUINARINE Dihydrochelerythrine Chelerythrine 6-Methoxyldihydrochelerythrine chloride Ethoxysanguinarine

angoline

12,13-Dihydro-1,2,13-trimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridine

6-Methoxyldihydrochelerythrine

[1,3]Benzodioxolo[5,6-c]phenanthridine, 12,13-dihydro-1,2,13-trimethoxy-12-methyl-

phosphorylation,proliferation,STAT3,anticancer,inhibit,Angoline,Inhibitor,STAT,IL-6

6-Methoxydihydrocheleryth

1,2,13-Trimethoxy-12-methyl-12,13-dihydro-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridine

Angoline, 10 mM in DMSO

1,2,13-Trimethoxy-12-methyl-12,13-dihydro-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridine

21080-31-9