ChemicalBook > CAS DataBase List > scopolin

scopolin

Product Name: scopolin
CAS No.: 531-44-2
Chemical Name: scopolin
Synonyms: 5Mg;Scopoletin glucoside;CPD-678;Murrayin;SCOPOLIN;FM-381 HCl;Scopoloside;GSK-690 HCl;Scopolin-RM;Scopolin, 99%min
CBNumber: CB21334346
Molecular Formula: C16H18O9
Formula Weight: 354.31
MOL File: 531-44-2.mol

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scopolin Property

Melting point:: 217℃
Boiling point:: 650.2±55.0 °C(Predicted)
Density: 1.552
storage temp.: 2-8°C
solubility: Soluble in DMSO
form: powder
pka: 12.71±0.70(Predicted)
color: White
InChI: InChI=1/C16H18O9/c1-22-9-4-7-2-3-12(18)23-8(7)5-10(9)24-16-15(21)14(20)13(19)11(6-17)25-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15-,16-/s3
InChIKey: SGTCGCCQZOUMJJ-ONCUFOQVNA-N
SMILES: O([C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)C1C=C2OC(=O)C=CC2=CC=1OC |&1:1,2,3,5,7,r|

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL82649
Product name: Scopolin
Purity: phyproof<SUP>®</SUP> Reference Substance
Packaging: 10 mg
Price: $313
Updated: 2025/07/31

TRC

Product number: S200520
Product name: Scopoletin7-O-Glucoside
Packaging: 10mg
Price: $185
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FS65518
Product name: Scopolin
Packaging: 25mg
Price: $200
Updated: 2021/12/16

AK Scientific

Product number: W1273
Product name: Scopolin
Packaging: 10mg
Price: $218
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FS65518
Product name: Scopolin
Packaging: 2mg
Price: $50
Updated: 2021/12/16

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scopolin Chemical Properties,Usage,Production

Chemical Properties

Soluble in methanol, ethanol, DMSO and other organic solvents, derived from diclofenac, dingongteng, scopolamine root, ningxia wolfberry, mulberry tree.

Uses

Scopoletin 7-O-glucoside is a derivative of Scopoletin (S200500), a common constituent found in a variety of plants that has potential to regulate hyperthyroidism in rats. Scopoletin 7-O-glucoside is a compound that is obtained from the methanolic extract of the fresh underground parts of the flower Scopolia japonica.

Definition

ChEBI: A member of the class of coumarins that is scopoletin attached to a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage.

in vivo

Scopolin (0.02% (w/w) in HFD diet, 8 weeks) decreases the body weight gain, and alleviates hepatic steatosis in HFD-fed mice^[2].
Scopolin (2 μmol, icv) increases the extracellular acetylcholine concentration in rat brain to about 300% compared to basal release^[3].
Scopolin (50, 100 mg/kg, i.p.) inhibits adjuvant-induced arthritis by inhibiting inflammation and angiogenesis in rats^[4].

Animal Model:	HFD-fed C57BL/6?N mice^[2]
Dosage:	0.02% (w/w) in HFD diet (equivalent to 20?mg/kg body weight)
Administration:	Supplemented in diet, 8 weeks
Result:	Reversed the HFD-induced hepatic TG, cholesterol, and fatty acid accumulation by 35%, 49%, and 35%, respectively. Reversed the HFD-induced decrease in plasma adiponectin levels by 76%, and reduced the increased plasma MCP-1, TNFα, and IL-6 levels. Restored HFD-induced downregulation of SIRT1 activity.

Animal Model:	Adjuvant-induced arthritis (AIA) rats^[4]
Dosage:	50, 100 mg/kg
Administration:	i.p.
Result:	Inhibited inoculated and non-inoculated paw swelling and articular index scores. Reduced new blood vessels, and reduced IL-6, VEGF and FGF-2 expressions in rat synovial tissues.

target

VEGFR | IL Receptor | AChR | Antifection

IC 50

SIRT1

scopolin Preparation Products And Raw materials

Raw materials

Preparation Products

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scopolin Suppliers

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View Lastest Price from scopolin manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: scopolin 531-44-2
Price: US $0.00-0.00/KG
Min. Order: 5mg
Purity: 99%HPLC
Supply Ability: 2000tons
Release date: 2020-01-07

Shaanxi Haibo Biotechnology Co., Ltd

Product: scopolin 531-44-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-08-24

Shanghai Standard Technology Co., Ltd.

Product: Scopolin 531-44-2
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-11-12

531-44-2, scopolinRelated Search:

MEDICAGOL pimpinellin 4-Hydroxycoumarin Anisodamine 6-ISOPENTENYLOXYISOBERGAPTEN 5,8-DIHYDROXYPSORALEN 5,7-Dihydroxy-4-methylcoumarin ANISODAMINE HYDROBROMIDE 5-Hydroxyxanthotoxin 4-METHYLESCULETIN Icariin Baicalin Vitexin XANTHOTOXOL(RG) SCOPARONE Scopoletin b-D-Glucuronide coniferin scopolin

Scopoletin 7-O-Glucoside

CPD-678

6-Methoxy-7-(beta-D-glucopyranosyloxy)coumarin

6-Methoxycoumarin 7-O-beta-D-glucoside

7-(beta-D-Glucopyranosyloxy)-6-methoxy-2H-1-benzopyran-2-one

7-(beta-D-Glucopyranosyloxy)-6-methoxycoumarin

5Mg

Murrayin

Scopoletin glucoside

Scopoloside

scopoletin-β-D-galactoside

2H-1-Benzopyran-2-one, 7-(β-D-glucopyranosyloxy)-6-methoxy-

6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one

steatosis,Inhibitor,coumarin,Arabidopsis,thaliana,Sirtuin,Scopolin,hepatic,inhibit

SCOPOLIN

FM-381 HCl

LQVTDSGLYRCVIYHPP TFA

GSK-690 HCl

Scopolin-RM

Ethyl Acetate Impurity 129

Scopolin, 10 mM in DMSO

Scopolin, 99%min

Scopoletin β-D-glucoside

531-44-2