bruceine E
- Product Name
- bruceine E
- CAS No.
- 21586-90-3
- Chemical Name
- bruceine E
- Synonyms
- Brucein E;20-Deoxybruceine F;2-O-Demethylbruceine M;Bruceine E, 10 mM in DMSO;13,20-Epoxy-1β,2α,11β,12α,14,15β-hexahydroxypicras-3-en-16-one;hypoglycemia,quassinoid,Bruceine E,effect,Inhibitor,antidiabetic,inhibit;Picras-3-en-16-one, 13,20-epoxy-1,2,11,12,14,15-hexahydroxy-, (1β,2α,11β,12α,15β)-;(1R,2S,3R,3aR,3a1R,4R,6aR,7aS,10S,11S,11aS)-1,2,3a,4,10,11-hexahydroxy-3,8,11a-trimethyl-2,3,3a,4,7,7a,10,11,11a,11b-decahydro-1H-3,3a1-(epoxymethano)dibenzo[de,g]chromen-5(6aH)-one;(1R,2S,3R,3aR,3a1R,4R,6aR,7aS,10S,11S,11aS,11bR)-1,2,3a,4,10,11-Hexahydroxy-3,8,11a-trimethyl-1,2,3,3a,4,6a,7,7a,10,11,11a,11b-dodecahydro-5H-3,3a1-(epoxymethano)dibenzo[de,g]chromen-5-one
- CBNumber
- CB21340189
- Molecular Formula
- C20H28O9
- Formula Weight
- 412.43
- MOL File
- 21586-90-3.mol
bruceine E Property
- form
- Solid
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- CFN89340
- Product name
- BruceineE
- Purity
- ≥98%
- Packaging
- 20mg
- Price
- $318
- Updated
- 2021/12/16
- Product number
- SY232747
- Product name
- BruceineE
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $477.27
- Updated
- 2021/12/16
bruceine E Chemical Properties,Usage,Production
Chemical Properties
White crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from the fruit of Brucea javanica.
Uses
Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect[1]. Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ (HY-13753))-induced diabetic rats at lower dose[2].
in vivo
Bruceine D and E, isolated from B. javanica seeds, exhibits blood glucose lowering effect in both nondiabetic mice and STZ-induced diabetic rats at lower dose (1 mg/kg b.w.) during 0-8 h screening[2].
References
[1] Man F, et al. HPLC-MS/MS method for bioavailability study of bruceines D & E in rat plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 15;1063:183-188. DOI:10.1016/j.jchromb.2017.08.037
[2] Ablat A, et al. Antidiabetic effects of Brucea javanica seeds in type 2 diabetic rats. BMC Complement Altern Med. 2017;17(1):94. Published 2017 Feb 6. DOI:10.1186/s12906-017-1610-x
bruceine E Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from bruceine E manufacturers
- Product
- bruceine E 21586-90-3
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg,5kg,50kg
- Release date
- 2020-01-18