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LY 223982

Product Name
LY 223982
CAS No.
117423-74-2
Chemical Name
LY 223982
Synonyms
CGS23131;LY 223982;SKF107324);LY223982,LY-223982;LY223982 Exclusive;SYZSSLLFRVDRHL-QPJJXVBHSA-N;LY223982 (Synonyms: CGS23131;5-(3-Carboxybenzoyl)-2-[(E)-6-(4-methoxyphenyl)-5-hexenyloxy]benzenepropanoic acid;Benzenepropanoic acid, 5-(3-carboxybenzoyl)-2-[[(5E)-6-(4-methoxyphenyl)-5-hexen-1-yl]oxy]-
CBNumber
CB21341434
Molecular Formula
C30H30O7
Formula Weight
502.55
MOL File
117423-74-2.mol
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LY 223982 Property

Melting point:
151-152 °C
Boiling point:
753.8±60.0 °C(Predicted)
Density 
1.235±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly, Heated, Sonicated), DMSO (Very Slightly)
form 
A crystalline solid
pka
3.81±0.10(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10010024
Product name
LY223982
Purity
≥98%
Packaging
1mg
Price
$28
Updated
2024/03/01
Cayman Chemical
Product number
10010024
Product name
LY223982
Purity
≥98%
Packaging
5mg
Price
$117
Updated
2024/03/01
Cayman Chemical
Product number
10010024
Product name
LY223982
Purity
≥98%
Packaging
10mg
Price
$207
Updated
2024/03/01
Cayman Chemical
Product number
10010024
Product name
LY223982
Purity
≥98%
Packaging
25mg
Price
$448
Updated
2024/03/01
TRC
Product number
L503108
Product name
LY223982
Packaging
1mg
Price
$40
Updated
2021/12/16
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LY 223982 Chemical Properties,Usage,Production

Description

Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from the 5-lipoxygenase pathway of arachidonic acid metabolism and is an important mediator of the inflammatory process. The benzophenone dicarboxylic acid derivative LY223982 is a potent BLT1 receptor antagonist. It inhibits the specific binding of radiolabeled-LTB4 to isolated human neutrophils with an IC50 value of 13.2 nM. LY223982 inhibits the leukotriene B4 (LTB4)-induced aggregation of guinea pig and human neutrophils with IC50 values of 74 and 100 nM, respectively. However, concentrations of LY223982 up to 10 μM do not inhibit binding of LTB4 to human BLT1 or BLT2 expressed in CHO cells.

Uses

LY223982 is a potent P2Y7 (BLT1) receptor antagonist.

LY 223982 Preparation Products And Raw materials

Raw materials

Preparation Products

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LY 223982 Suppliers

China 28 United States 8 Global 36
TargetMol Chemicals Inc.
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+1-781-999-5354 +1-00000000000
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marketing@targetmol.com
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United States
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TargetMol Chemicals Inc.
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+8613564774135
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zijue.cai@tsbiochem.com
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United States
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Aladdin Scientific
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sales@aladdinsci.com
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ApexBio Technology
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Cayman Chemical Company
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cayman@caymanchem.com
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United States
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6213
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United States Biological
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chemicals@usbio.net
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United States
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6214
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MedChemExpress
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117423-74-2, LY 223982Related Search:

LY 223982 3-(3-FORMYLPHENYL)PROPANOIC ACID METHOXYPHENONE 4-METHOXY-3'-METHYLBENZOPHENONE 3-(2-METHOXYPHENYL)PROPIONIC ACID

  • LY 223982
  • 5-(3-Carboxybenzoyl)-2-[(E)-6-(4-methoxyphenyl)-5-hexenyloxy]benzenepropanoic acid
  • SYZSSLLFRVDRHL-QPJJXVBHSA-N
  • LY223982 Exclusive
  • LY223982 (Synonyms: CGS23131
  • SKF107324)
  • CGS23131
  • Benzenepropanoic acid, 5-(3-carboxybenzoyl)-2-[[(5E)-6-(4-methoxyphenyl)-5-hexen-1-yl]oxy]-
  • LY223982,LY-223982
  • 117423-74-2