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hamaudol

Product Name
hamaudol
CAS No.
735-46-6
Chemical Name
hamaudol
Synonyms
hamaudol;Inhibitor,COX,Hamaudol,Cyclooxygenase,inhibit;(S)-3,5-Dihydroxy-2,2,8-trimethyl-3,4-dihydro-2H,6H-pyrano[3,2-g]chromen-6-one;(S)-3,4-Dihydro-3β,5-dihydroxy-2,2,8-trimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one;2H,6H-Benzo[1,2-b:5,4-b']dipyran-6-one, 3,4-dihydro-3,5-dihydroxy-2,2,8-trimethyl-, (3S)-
CBNumber
CB21363984
Molecular Formula
C15H16O5
Formula Weight
276.28
MOL File
735-46-6.mol
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hamaudol Property

Melting point:
197.0-197.5 °C
Boiling point:
464.7±45.0 °C(Predicted)
Density 
1.336±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
pka
6.77±0.70(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0100499
Product name
Hamaudol
Packaging
5mg
Price
$336
Updated
2021/12/16
ChemScene
Product number
CS-0100499
Product name
Hamaudol
Packaging
10mg
Price
$571
Updated
2021/12/16
Biorbyt Ltd
Product number
orb594459
Product name
Hamaudol
Packaging
20mg
Price
$591.6
Updated
2021/12/16
Biorbyt Ltd
Product number
orb594459
Product name
Hamaudol
Packaging
100mg
Price
$1757.8
Updated
2021/12/16
AK Scientific
Product number
1210CB
Product name
Hamaudol
Packaging
500mg
Price
$4775
Updated
2021/12/16
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hamaudol Chemical Properties,Usage,Production

Definition

ChEBI: Hamaudol is a member of chromenes.

Biological Activity

Hamaudol is a chromone isolated from Saposhnikovia divaricata. It has obvious inhibitory ability on the activities of cyclooxygenase (COX)-1 and COX-2 with IC50 values of 0.30 and 0.57 mM, respectively, and has potent analgesic and anti-inflammatory effects.

in vivo

Hamaudol (Compound 7) increases the potency to exhibit a potent analgesia at doses of 1, 5 and 10 mg/kg in mice, although it do not show clear dose dependency.

< b>

target

COX-1

< span> 0.3 mM (IC 50 )

COX-2

0.57 mM (IC 50 )

hamaudol Preparation Products And Raw materials

Raw materials

Preparation Products

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hamaudol Suppliers

China 28 United States 3 Global 31
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7887
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
7059
Advantage
55
Shanghai Changyan Chem & Tech Co., Ltd.
Tel
021-20242659 18930833303
Fax
+86 (21) 2024-2659
Email
Sales@changyanchem.cn
Country
China
ProdList
5010
Advantage
55
Chengdu Push Bio-Technology Co., Ltd.
Tel
028-85370565-229 18080489829
Email
3004654993@qq.com
Country
China
ProdList
8899
Advantage
60
Shanghai Standard Technology Co.,Ltd.
Tel
021-021-57127007-6622-6622 15618937986
Fax
+86 (21) 5132-0077
Email
zhaok@nature-standard.com
Country
China
ProdList
3016
Advantage
58
Nanjing Digger Medical Technology Co. Ltd.
Tel
025-025-51191215 18013836722
Fax
025-51191215
Email
2399235533@qq.com
Country
China
ProdList
4933
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58

735-46-6, hamaudolRelated Search:

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  • hamaudol
  • (S)-3,4-Dihydro-3β,5-dihydroxy-2,2,8-trimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one
  • 2H,6H-Benzo[1,2-b:5,4-b']dipyran-6-one, 3,4-dihydro-3,5-dihydroxy-2,2,8-trimethyl-, (3S)-
  • Inhibitor,COX,Hamaudol,Cyclooxygenase,inhibit
  • (S)-3,5-Dihydroxy-2,2,8-trimethyl-3,4-dihydro-2H,6H-pyrano[3,2-g]chromen-6-one
  • 735-46-6