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hamaudol

Product Name
hamaudol
CAS No.
735-46-6
Chemical Name
hamaudol
Synonyms
hamaudol;Inhibitor,COX,Hamaudol,Cyclooxygenase,inhibit;(S)-3,5-Dihydroxy-2,2,8-trimethyl-3,4-dihydro-2H,6H-pyrano[3,2-g]chromen-6-one;(S)-3,4-Dihydro-3β,5-dihydroxy-2,2,8-trimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one;2H,6H-Benzo[1,2-b:5,4-b']dipyran-6-one, 3,4-dihydro-3,5-dihydroxy-2,2,8-trimethyl-, (3S)-
CBNumber
CB21363984
Molecular Formula
C15H16O5
Formula Weight
276.28
MOL File
735-46-6.mol
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hamaudol Property

Melting point:
197.0-197.5 °C
Boiling point:
464.7±45.0 °C(Predicted)
Density 
1.336±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
pka
6.77±0.70(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0100499
Product name
Hamaudol
Packaging
5mg
Price
$336
Updated
2021/12/16
ChemScene
Product number
CS-0100499
Product name
Hamaudol
Packaging
10mg
Price
$571
Updated
2021/12/16
Biorbyt Ltd
Product number
orb594459
Product name
Hamaudol
Packaging
20mg
Price
$591.6
Updated
2021/12/16
Biorbyt Ltd
Product number
orb594459
Product name
Hamaudol
Packaging
100mg
Price
$1757.8
Updated
2021/12/16
AK Scientific
Product number
1210CB
Product name
Hamaudol
Packaging
500mg
Price
$4775
Updated
2021/12/16
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hamaudol Chemical Properties,Usage,Production

Definition

ChEBI: Hamaudol is a member of chromenes.

Biological Activity

Hamaudol is a chromone isolated from Saposhnikovia divaricata. It has obvious inhibitory ability on the activities of cyclooxygenase (COX)-1 and COX-2 with IC50 values of 0.30 and 0.57 mM, respectively, and has potent analgesic and anti-inflammatory effects.

in vivo

Hamaudol (Compound 7) increases the potency to exhibit a potent analgesia at doses of 1, 5 and 10 mg/kg in mice, although it do not show clear dose dependency.

< b>

target

COX-1

< span> 0.3 mM (IC 50 )

COX-2

0.57 mM (IC 50 )

hamaudol Preparation Products And Raw materials

Raw materials

Preparation Products

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hamaudol Suppliers

China 28 United States 3 Global 31
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38632
Advantage
58
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58

735-46-6, hamaudolRelated Search:

GARDENIN B PONCIRIN Quercetin-7-O-β-D-glucopyranoside MEDICAGOL MOSLOFLAVONE hydroxygenkwanin CIMIFUGIN BETA-D-GLUCOPYRANOSIDE 4-O-BETA-D-GULCOSYL-5-O-METHYLVISAMMINOL 4',5-DIHYDROXY-7-METHOXYFLAVONE 3-O-Acetylhamaudol 5-O-Methylvisammioside, 6''-O-apiosyl- SEC-O-GLUCOSYLHAMAUDOL 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one Naringenin Naringenin 7-O-β-D-Glucuronide (Mixture of Diastereomers)

  • hamaudol
  • (S)-3,4-Dihydro-3β,5-dihydroxy-2,2,8-trimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one
  • 2H,6H-Benzo[1,2-b:5,4-b']dipyran-6-one, 3,4-dihydro-3,5-dihydroxy-2,2,8-trimethyl-, (3S)-
  • Inhibitor,COX,Hamaudol,Cyclooxygenase,inhibit
  • (S)-3,5-Dihydroxy-2,2,8-trimethyl-3,4-dihydro-2H,6H-pyrano[3,2-g]chromen-6-one
  • 735-46-6