4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene
- Product Name
- 4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene
- CAS No.
- 112241-19-7
- Chemical Name
- 4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene
- Synonyms
- 4-Succinimidyloxycarbonyl-α-Methyl-α-(2-Pyridyldithio)toluene;4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene;2,5-Dioxopyrrolidin-1-yl 4-[1-(pyridin-2-yldisulfanyl)ethyl]benzoate;2,5-dioxopyrrolidin-1-yl 4-(1-(pyridin-2-yldisulfaneyl)ethyl)benzoate;Benzoic acid, 4-[1-(2-pyridinyldithio)ethyl]-, 2,5-dioxo-1-pyrrolidinyl ester
- CBNumber
- CB21374227
- Molecular Formula
- C18H16N2O4S2
- Formula Weight
- 388.46
- MOL File
- 112241-19-7.mol
4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene Property
- storage temp.
- 2-8°C
- solubility
- Soluble in DMSO
- form
- Solid
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 803472
- Product name
- SMPT (4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene)
- Packaging
- 50MG
- Price
- $484
- Updated
- 2023/06/20
- Product number
- S688098
- Product name
- 4-Succinimidyloxycarbonyl-α-methyl-α-(2-pyridyldithio)toluene
- Packaging
- 10mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- CS-0103518
- Product name
- SMPT
- Packaging
- 100mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- 40-0198
- Product name
- 2,5-Dioxopyrrolidin-1-yl4-(1-(pyridin-2-yldisulfanyl)ethyl)benzoate
- Purity
- >95%
- Packaging
- 250mg
- Price
- $590
- Updated
- 2021/12/16
- Product number
- 112241197
- Product name
- 4-Succinimidyloxycarbonyl-alpha-methyl-alpha-(2-pyridyldithio)toluene
- Packaging
- 1g
- Price
- $1088.78
- Updated
- 2021/12/16
4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene Chemical Properties,Usage,Production
General Description
SMPT is a heterobifunctional sulfhydryl- and amine-reactive cross-linker. SMPT is used often for conjugating a toxin molecule to a monoclonal antibody directed against a cell-surface antigen. These immunotoxins produced with SMPT are highly potent as the cleavable disulfide imparts increased cytotoxicity compared to conjugates without a cleavable bond, such as those produced with SPDP. Also, next to the pyridine-2-thione in the spacer arm are a benzene ring and a methyl group adjacent to a carbon that hinders the disulfide bond, allowing exceptional conjugate stability in vivo. SMPT has the added benefit of being more stable to hydrolysis in aqueous solutions than other NHS cross-linkers.
4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene Preparation Products And Raw materials
Raw materials
Preparation Products
4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene Suppliers
- Tel
- --
- Fax
- --
- sales21@chemicalland21.com
- Country
- South Korea
- ProdList
- 6303
- Advantage
- 74
View Lastest Price from 4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene manufacturers
- Product
- SMPT 112241-19-7
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- >95.00%
- Supply Ability
- 100mg
- Release date
- 2024-03-21
- Product
- SMPT 112241-19-7
- Price
- US $0.00-0.00/mg
- Min. Order
- 50mg
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2021-09-15