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phycocyanobilin

Product Name
phycocyanobilin
CAS No.
20298-86-6
Chemical Name
phycocyanobilin
Synonyms
Spirullina;phycocyanobilin;3(E)-Phycocyanobilin;Phycocyanobilin - PCB;Phycocyanobilin (Protein mixture);Phycocyanobilin (Microbial source);21H-Biline-8,12-dipropanoic acid, 18-ethyl-3-ethylidene-1,2,3,19,22,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-, (2R,3E)-;(2R,3E,4Z,10Z,15Z)-18-Ethyl-3-ethylidene-1,2,3,19,22,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid;-[2-[(Z)-[(5E)-3-(2-carboxyethyl)-5-[(4-ethyl-3-methyl-5-oxo-pyrrol-2-yl)methylene]-4-methyl-pyrrol-2-ylidene]methyl]-5-[(Z)-[(3E,4R)-3-ethylidene-4-methyl-5-oxo-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid;3-((Z)-2-((3-(2-Carboxyethyl)-5-((Z)-((R,E)-3-ethylidene-4-methyl-5-oxopyrrolidin-2-ylidene)methyl)-4-methyl-1H-pyrrol-2-yl)methylene)-5-((Z)-(4-ethyl-3-methyl-5-oxo-1H-pyrrol-2(5H)-ylidene)methyl)-4-methyl-2H-pyrrol-3-yl)propanoic acid
CBNumber
CB21380404
Molecular Formula
C33H38N4O6
Formula Weight
586.69
MOL File
20298-86-6.mol
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phycocyanobilin Property

Boiling point:
892.1±65.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
pka
4.47±0.10(Predicted)
form 
Solid
color 
Blue to dark blue
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Frontier Specialty Chemicals
Product number
P14137
Product name
Phycocyanobilin(microbialsource)
Purity
>95%
Packaging
5mg
Price
$119
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
P14137
Product name
Phycocyanobilin(microbialsource)
Purity
>95%
Packaging
25mg
Price
$432
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
P14137
Product name
Phycocyanobilin(microbialsource)
Purity
>95%
Packaging
50mg
Price
$785
Updated
2021/12/16
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phycocyanobilin Chemical Properties,Usage,Production

Uses

Phycocyanobilin, an orally active antioxidative agent, is an effective scavenger for various reactive oxygen species. Phycocyanobilin can be used for the research of Alzheimer’s disease[1][2][3].

in vivo

Phycocyanobilin (15 mg/kg; p.o.; in diet for 2 weeks) shows antioxidant effects in type 2 diabetes mice[3].

Animal Model:Male C57BL/Ks J db/db mice, a rodent model for type 2 diabetes[3]
Dosage:15 mg/kg
Administration:In diet for 2 weeks
Result:Significantly decreased blood glucose levels. Normalized the increases in urinary 8-OHdG and 8-epi-PGF2α levels, renal oxidative stress markers evaluated by renal 8-OHdG staining and DHE staining, Nox4 mRNA, and protein expression, as well as the mRNA levels of other NAD(P)H oxidase components, inflammatory markers and HO-1.

Enzyme inhibitor

This linear tetrapyrrole (FW = 559.64 g/mol) is a prosthetic group of blue, highly fluorescent photoreceptor pigments (phycocyanins) found in certain algae. It is soluble in water and polar organic solvents. Phycocyanins, found in Cyanophyta, are proteins, which typically contain three molecules of covalently bound phycocyanobilin per subunit. One molecule of phycocyanobilin is bound per molecule of allophycocyanin, found in Cyanophyta and Rhodophyta. Phycocyanins and their chromophore phycocyanobilin are peroxy radical scavengers and inhibits ONOO–- mediated biological effects. Target(s): cyclooxygenase-2, inhibited by C-phycocyanin and poorly by phycocyanobilin.

References

[1] Hirata T, et al. Antioxidant activities of phycocyanobilin prepared from Spirulina platensis. Journal of Applied Phycology, 2000, 12: 435-439.
[2] Matamoros BP, et al. Nutraceutical and therapeutic potential of Phycocyanobilin for treating Alzheimer's disease. J Biosci. 2021;46:42. PMID:34047285
[3] Zheng J, et al. Phycocyanin and phycocyanobilin from Spirulina platensis protect against diabetic nephropathy by inhibiting oxidative stress. Am J Physiol Regul Integr Comp Physiol. 2013 Jan 15;304(2):R110-20. DOI:10.1152/ajpregu.00648.2011

phycocyanobilin Preparation Products And Raw materials

Raw materials

Preparation Products

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phycocyanobilin Suppliers

China 45 United States 1 Global 46
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chengdu Aslee Biopharmaceuticals, Inc
Tel
028-85305008 02885305008
Fax
4000210878-186
Email
2306208234@qq.com
Country
China
ProdList
1006
Advantage
50
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31553
Advantage
55
Xi'an boliante Chemical Co., Ltd.
Tel
17719597442
Fax
-
Email
642232259@qq.com
Country
China
ProdList
449
Advantage
58
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17987
Advantage
58
Henan Alfachem Co.,Ltd.
Tel
0371-55051623 18137891487
Fax
QQ：2853979817
Email
2853979817@qq.com
Country
China
ProdList
9984
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57422
Advantage
58
Shandong Zhishang New Material Co., Ltd.
Tel
+8617653113209
Email
sales002@sdzschem.com
Country
China
ProdList
3049
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
Block Chemical Technology (Shanghai) Co., Ltd.
Tel
021-20432219 13918097649
Fax
QQ79021576
Email
li_jinfei@acblock-lab.com
Country
China
ProdList
10034
Advantage
58
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View Lastest Price from phycocyanobilin manufacturers

Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.
Product
Spirulina powder 20298-86-6
Price
US $17.00/KG
Min. Order
1KG
Purity
55% and 77%
Supply Ability
1mt
Release date
2020-09-07
Shaanxi Dideu Medichem Co. Ltd
Product
phycocyanobilin 20298-86-6
Price
US $1.00-1.00/Kg
Min. Order
1KG
Purity
99.0%
Supply Ability
800 tons
Release date
2020-04-21

20298-86-6, phycocyanobilinRelated Search:

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  • 3(E)-Phycocyanobilin
  • Phycocyanobilin (Microbial source)
  • Phycocyanobilin - PCB
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  • -[2-[(Z)-[(5E)-3-(2-carboxyethyl)-5-[(4-ethyl-3-methyl-5-oxo-pyrrol-2-yl)methylene]-4-methyl-pyrrol-2-ylidene]methyl]-5-[(Z)-[(3E,4R)-3-ethylidene-4-methyl-5-oxo-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
  • 3-((Z)-2-((3-(2-Carboxyethyl)-5-((Z)-((R,E)-3-ethylidene-4-methyl-5-oxopyrrolidin-2-ylidene)methyl)-4-methyl-1H-pyrrol-2-yl)methylene)-5-((Z)-(4-ethyl-3-methyl-5-oxo-1H-pyrrol-2(5H)-ylidene)methyl)-4-methyl-2H-pyrrol-3-yl)propanoic acid
  • Phycocyanobilin (Protein mixture)
  • 20298-86-6
  • SiChem