Methyl 3-(4-hydroxyphenyl)propionate

Product Name: Methyl 3-(4-hydroxyphenyl)propionate
CAS No.: 5597-50-2
Chemical Name: Methyl 3-(4-hydroxyphenyl)propionate
Synonyms: Methyl 3-(4-hydroxyphenyl)propanoate;4-hydroxy-benzenepropanoic acid methyl ester;Methyl 4-hydroxyhydrocinnamate;Methyl p-hydroxyphenylpropionate;Esmolol Impurity 11 HCl;METHYL P-HYDROXYHYDROCINNAMATE;Methyl 4-hydroxyphenylpropionate;Methyl 3-(4-hydroxyphenyl)propiote;p-Dihydrocoumaric acid methyl ester;Methyl 3-(p-hydroxyphenyl)propionate
CBNumber: CB2138477
Molecular Formula: C10H12O3
Formula Weight: 180.2
MOL File: 5597-50-2.mol

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Methyl 3-(4-hydroxyphenyl)propionate Property

Melting point:: 39-41 °C (lit.)
Boiling point:: 108 °C/11 mmHg (lit.)
Density: 1.1272 (rough estimate)
refractive index: 1.5160 (estimate)
Flash point:: >230 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Soluble in chloroform and methanol.
form: Powder
pka: 9.89±0.15(Predicted)
color: White transparent
CAS DataBase Reference: 5597-50-2(CAS DataBase Reference)
NIST Chemistry Reference: Benzenepropanoic acid, 4-hydroxy-, methyl ester(5597-50-2)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39
WGK Germany: 3
HS Code: 29181990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 360910
Product name: Methyl 3-(4-hydroxyphenyl)propionate
Purity: 97%
Packaging: 5g
Price: $50.1
Updated: 2025/07/31

TCI Chemical

Product number: M2196
Product name: Methyl 3-(4-Hydroxyphenyl)propionate
Purity: >98.0%(GC)
Packaging: 5g
Price: $20
Updated: 2025/07/31

TCI Chemical

Product number: M2196
Product name: Methyl 3-(4-Hydroxyphenyl)propionate
Purity: >98.0%(GC)
Packaging: 25g
Price: $75
Updated: 2025/07/31

TRC

Product number: H949495
Product name: 3-(4-Hydroxyphenyl)propionicAcidMethylEster
Packaging: 2.5g
Price: $135
Updated: 2021/12/16

TRC

Product number: H949495
Product name: 3-(4-Hydroxyphenyl)propionicAcidMethylEster
Packaging: 10g
Price: $155
Updated: 2021/12/16

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Methyl 3-(4-hydroxyphenyl)propionate Chemical Properties,Usage,Production

Chemical Properties

white transparent low melting mass

Uses

Methyl 3-(4-hydroxyphenyl)propionate may be used in the enzymatic coupling of saccharides to protein.

Definition

ChEBI: Methyl 3-(4-hydroxyphenyl)propionate is a methyl ester resulting from the formal condensation of the carboxy group of phloretic acid with methanol. It is a nitrification inhibitor and a plant growth regulator. It has a role as a nitrification inhibitor and a plant growth regulator. It is a member of phenols and a methyl ester. It is functionally related to a phloretic acid.

General Description

Methyl 3-(4-hydroxyphenyl)propionate is reported to be responsible for biological nitrification inhibition in sorghum (Sorghum bicolor).

Synthesis

3943-97-3

5597-50-2

General procedure for the synthesis of methyl 4-hydroxyphenylpropionate from methyl 4-hydroxycinnamate: Pd/C (0.1 g) was added to a solution of methyl (E)-3-(4-hydroxyphenyl)acrylate (1.0 g, 5.6 mmol) in ethanol (20 mL). The reaction mixture was stirred vigorously at room temperature under hydrogen atmosphere (1 bar) for 21 hours. Upon completion of the reaction, the suspension was filtered through a diatomaceous earth pad and evaporated to dryness under vacuum to afford the oily product methyl 3-(4-hydroxyphenyl)propionate (1.0 g, 5.6 mmol, 99% yield). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 7.07 (ddd, J=8.8,2.8,2.0 Hz, 2H), 6.76 (ddd, J=8.8,2.8,2.0 Hz, 2H), 4.72 (br s, 1H), 3.67 (s, 3H), 2.88 (t, J=7.8 Hz, 2H). 2.60 (t, J=7.8Hz, 2H).

References

[1] Journal of Natural Products, 1999, vol. 62, # 1, p. 102 - 106
[2] Patent: EP2745876, 2014, A1. Location in patent: Page/Page column
[3] Patent: US2015/344408, 2015, A1. Location in patent: Paragraph 0413-0415
[4] Journal of Agricultural and Food Chemistry, 2007, vol. 55, # 26, p. 10635 - 10640
[5] Angewandte Chemie - International Edition, 2014, vol. 53, # 30, p. 7785 - 7788

Methyl 3-(4-hydroxyphenyl)propionate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 3-(4-hydroxyphenyl)propionate Suppliers

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View Lastest Price from Methyl 3-(4-hydroxyphenyl)propionate manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: Methyl 3-(4-hydroxyphenyl)propionate 5597-50-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-12-02

Henan Aochuang Chemical Co.,Ltd.

Product: Methyl 3-(4-hydroxyphenyl)propionate 5597-50-2
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-28

Shaanxi Dideu Medichem Co. Ltd

Product: Methyl 3-(4-hydroxyphenyl)propionate 5597-50-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000kg
Release date: 2024-08-01

5597-50-2, Methyl 3-(4-hydroxyphenyl)propionateRelated Search:

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METHYL 3-(4-HYDROXYPHENYL)PROPIONATE

METHYL P-HYDROXYHYDROCINNAMATE

4-hydroxy-benzenepropanoic acid methyl ester

3-(4-HYDROXYPHENYL)PROPIONIC ACID METHYL ESTER

3-(4'-HYDROXYPHENYL)-PROPIONIC ACID-OME

3-(4-HYDROXY-PHENYL)-PROPIONIC ACID-OME

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Methyl 4-hydroxyphenylpropionate

METHYL 3-(4-HYDROXYPHENYL)PROPIONATE, 97 %

4-Hydroxyphenylpropionic Acid Methyl Ester

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3-(4-Hydroxyphenyl)propanoic acid methyl ester

4-Hydroxybenzenepropionic acid methyl ester

p-Dihydrocoumaric acid methyl ester

p-Hydroxyhydrocinnamic acid methyl ester

Methyl 3-(4-hydroxyphenyl)propionate,98%

Methyl 3-(4-hydroxyphenyl)propionate 97%

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3-methyl-2,3-dihydro-1-benzofuran-7-carboxylic acid

3-tert-butyl-5-(phenylmethyl)pyrazolidine

Methyl3-(4-Hydroxyphenyl)propionate&gt

Esmolol Impurity 11 HCl

Methyl 3-(4-hydroxyphenyl)propiote

5597-50-2

HOC6H4CH2CH2CO2CH3

Esters

Organic Building Blocks

C10 to C11

Carbonyl Compounds

Building Blocks

Aromatic Esters

(intermediate of esmolol)

C10 to C11

Carbonyl Compounds

Esters

Acids and Derivatives

Alcohols and Derivatives