ochnaflavone
- Product Name
- ochnaflavone
- CAS No.
- 50276-96-5
- Chemical Name
- ochnaflavone
- Synonyms
- ochnaflavone;Ochinaflavone;Similar to pyriloxanone -7-O- -d - glucopyranoside;2-[4-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-hydroxyphenoxy]phenyl]-5,7-dihydroxychromen-4-one;2-[4-[5-(5,7-Dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenoxy]phenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2-[4-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenoxy]phenyl]-5,7-dihydroxy-
- CBNumber
- CB21387317
- Molecular Formula
- C30H18O10
- Formula Weight
- 538.46
- MOL File
- 50276-96-5.mol
ochnaflavone Property
- Boiling point:
- 832.1±65.0 °C(Predicted)
- Density
- 1.622
- storage temp.
- 2-8°C
- pka
- 6.49±0.40(Predicted)
N-Bromosuccinimide Price
- Product number
- PXT0003631
- Product name
- OCHNAFLAVONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.11
- Updated
- 2021/12/16
- Product number
- orb105521
- Product name
- Ochnaflavone
- Purity
- >98%
- Packaging
- 20mg
- Price
- $569.5
- Updated
- 2021/12/16
- Product number
- 100419
- Product name
- Ochnaflavone
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $742
- Updated
- 2021/12/16
- Product number
- 6882AB
- Product name
- Ochnaflavone
- Packaging
- 250mg
- Price
- $1051
- Updated
- 2021/12/16
- Product number
- 100419
- Product name
- Ochnaflavone
- Purity
- 95+%
- Packaging
- 1g
- Price
- $1647
- Updated
- 2021/12/16
ochnaflavone Chemical Properties,Usage,Production
Uses
Ochnaflavone is an inhibitor of IIA-type secretory phospholipase A2 (sPLA2-IIA) with an IC50 of 3.45 μM. Ochnaflavone exhibits significant anti-inflammatory and liver-protective effects, capable of inhibiting the degradation of phosphatidylethanolamine (PE) and lipid peroxidation induced by carbon tetrachloride (CCl4) in rat liver, with an IC50 of 7.16 μM for lipid peroxidation. Ochnaflavone can be used in research on liver damage and inflammatory diseases[1].
Definition
ChEBI: Ochnaflavone is a biflavonoid with an ether linkage between the B-rings of the apigenin and luteolin subunits. It has been isolated from several members of the Ochnaceae plant family. It has a role as a plant metabolite, an antibacterial agent, a leukotriene antagonist, an anti-inflammatory agent, an EC 3.1.1.4 (phospholipase A2) inhibitor and an antiatherogenic agent. It is a biflavonoid, an aromatic ether and a hydroxyflavone. It is functionally related to a luteolin and an apigenin.
IC 50
sPLA2: 3.45 μM (IC50)
References
[1] Moon TC, et al. Ochnaflavone, naturally occurring biflavonoid, inhibits phospholipase A2 dependent phosphatidylethanolamine degradation in a CCl4-induced rat liver microsome. Biol Pharm Bull. 2006 Dec;29(12):2359-61. DOI:10.1248/bpb.29.2359
ochnaflavone Preparation Products And Raw materials
Raw materials
Preparation Products
ochnaflavone Suppliers
- Tel
- 027-87465837 19945049750
- Fax
- 027-8777-2287
- sales@finetechnology-ind.com
- Country
- China
- ProdList
- 9637
- Advantage
- 58
- Tel
- 86-021-61559134 15921386130
- Fax
- 021-55068248
- 3423497944@qq.com
- Country
- China
- ProdList
- 8144
- Advantage
- 55
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 021-61847300 13341622919
- Fax
- 021-61847300
- shcss01@163.com
- Country
- China
- ProdList
- 4808
- Advantage
- 58
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- +86-400-002-6226 +86-13028896684;
- sales@rrkchem.com
- Country
- China
- ProdList
- 57422
- Advantage
- 58
- Tel
- +86-27-8746-5837 +8619945049750
- Fax
- 86 27 87772287
- info@finetechnology-ind.com
- Country
- China
- ProdList
- 9629
- Advantage
- 58
- Tel
- +86-27-50766799 +8618062016861
- contact@labnetwork.com
- Country
- China
- ProdList
- 19987
- Advantage
- 58
- Tel
- 18871490254
- Fax
- 027-59599243
- linda@hubeijusheng.com
- Country
- CHINA
- ProdList
- 28172
- Advantage
- 58
- Tel
- 18616526224
- lianshuo@vip.126.com
- Country
- China
- ProdList
- 9607
- Advantage
- 58