galiellalactone
- Product Name
- galiellalactone
- CAS No.
- 133613-71-5
- Chemical Name
- galiellalactone
- Synonyms
- galiellalactone;SOIISBQQYAGDKM-QJSROADHSA-N;(4S,5aR,7aR,7bS)-5,5a,6,7,7a,7b-Hexahydro-7b-hydroxy-4-methylindeno[1,7-bc]furan-2(4H)-one;Indeno[1,7-bc]furan-2(4H)-one, 5,5a,6,7,7a,7b-hexahydro-7b-hydroxy-4-methyl-, (4S,5aR,7aR,7bS)-
- CBNumber
- CB21397587
- Molecular Formula
- C11H14O3
- Formula Weight
- 194.23
- MOL File
- 133613-71-5.mol
galiellalactone Property
- Boiling point:
- 400.7±38.0 °C(Predicted)
- Density
- 1.29±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO:0.97(Max Conc. mg/mL);4.99(Max Conc. mM)
Ethanol:0.97(Max Conc. mg/mL);4.99(Max Conc. mM) - form
- White to light tan solid.
- pka
- 12.48±0.40(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- 15387
- Product name
- Galiellalactone
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $371
- Updated
- 2024/03/01
- Product number
- 15387
- Product name
- Galiellalactone
- Packaging
- 500μg
- Price
- $219
- Updated
- 2024/03/01
- Product number
- 15387
- Product name
- Galiellalactone
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $1196
- Updated
- 2024/03/01
- Product number
- 6218
- Product name
- Galiellalactone
- Purity
- ≥95%(HPLC)
- Packaging
- 500U
- Price
- $229
- Updated
- 2021/12/16
- Product number
- G1044-62
- Product name
- Galiellalactone
- Packaging
- 1mg
- Price
- $523
- Updated
- 2021/12/16
galiellalactone Chemical Properties,Usage,Production
Description
Galiellalactone is a fungal metabolite isolated from the ascomycetes G. rufa strain A75-
Uses
Galiellalactone was originally isolated from Galiella rufa as a plant growth regulator. Recently it was shown to inhibit IL-6 induced SEAP expression with IC50 values of 250-500 nM, blocking the binding of the activated Stat3 dimers to their DNA binding sites without inhibiting the tyrosine and serine phosphorylation of the Stat3 transcription factor.
Uses
Galiellalactone is a STAT3 inhibitor; active in vivo. Galiellalactone is also a promising compound for the development of future prostate cancer drugs.
storage
Store at -20°C
galiellalactone Preparation Products And Raw materials
Raw materials
Preparation Products
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