heptelidic acid

Product Name: heptelidic acid
CAS No.: 57710-57-3
Chemical Name: heptelidic acid
Synonyms: Avocettin;Koningic acid;heptelidic acid;(5aS,9S)-1,5aβ,6,7,8,9aα-Hexahydro-6β-isopropyl-1-oxospiro[2-benzoxepine-9(3H),2'-oxirane]-4-carboxylic acid;(5aS,9S)-1,5a,6,7,8,9aα-Hexahydro-6β-(1-methylethyl)-1-oxospiro[2-benzoxepine-9(3H),2'-oxirane]-4-carboxylic acid;Spiro[2-benzoxepin-9(3H),2'-oxirane]-4-carboxylic acid, 1,5a,6,7,8,9a-hexahydro-6-(1-methylethyl)-1-oxo-, (2'S,5aS,6R,9aS)-
CBNumber: CB21398115
Molecular Formula: C15H20O5
Formula Weight: 280.32
MOL File: 57710-57-3.mol

More

Less

heptelidic acid Property

Boiling point:: 501.1±50.0 °C(Predicted)
Density: 1.27±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
form: A solid
pka: 3.68±0.40(Predicted)
color: Colorless to off-white
LogP: 2.034 (est)

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 14079
Product name: Heptelidic Acid
Purity: ≥95%
Packaging: 250μg
Price: $127
Updated: 2024/03/01

Cayman Chemical

Product number: 14079
Product name: Heptelidic Acid
Purity: ≥95%
Packaging: 1mg
Price: $397
Updated: 2024/03/01

Usbiological

Product number: 044883
Product name: Heptelidic acid
Packaging: 250ug
Price: $350
Updated: 2021/12/16

Usbiological

Product number: 169990
Product name: Heptelidic Acid
Packaging: 250ug
Price: $378
Updated: 2021/12/16

TRC

Product number: H281015
Product name: HeptelidicAcid
Packaging: 2.5mg
Price: $2145
Updated: 2021/12/16

More

Less

heptelidic acid Chemical Properties,Usage,Production

Uses

Heptalidic acid is a?sesquiterpene lactone and found to inhibit etoposide-induced apoptosis in human leukemia U937 cells. In addition, it also?inhibit mammalian DNA polymerases and terminal deoxynucleotidyl transferase.

in vivo

Heptelidic acid (Koningic acid; KA) is bioavailable and induces dynamic changes to glycolysis in vivo^[3].

Animal Model:	6-week old female Foxn1^nu mice bearing BT-474 tumor^[3]
Dosage:	1, 2.5, 5, and 10 mg/kg
Administration:	Daily intraperitoneal (IP) injections, 24 hours
Result:	1 mg/kg was determined to be the maximum tolerated dose (MTD) based upon behavioral monitoring and adverse events at higher doses (hemolysis, hematuria, and anemia).

IC 50

Caspase-3

heptelidic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

heptelidic acid Suppliers

China 44 India 1 United States 3 USA 1 Global 49

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19552
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Shanghai Universal Biotech Co.,Ltd

Tel: 15921930842 15921930842
Email: yh-wang@univ-bio.com
Country: China
ProdList: 25004
Advantage: 58

Zhejiang Huida Biotech Co., LTD

Tel: 0571-0571-89903882 15990081639
Email: sunshixuan@huidabiotech.com
Country: China
ProdList: 3705
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

57710-57-3, heptelidic acidRelated Search:

ETHYL (S)-3,4-EPOXYBUTANOATE ETHYL 2-HYDROXYCYCLOHEXANECARBOXYLATE (2E)-3-CYCLOHEXYLPROP-2-ENOIC ACID ALLYL 2-ETHYLBUTYRATE 3-(2-ethylbutoxy)propionic acid ETHYL (1S,2S)-TRANS-2-HYDROXYCYCLOHEXANECARBOXYLATE heptelidic acid

heptelidic acid

(5aS,9S)-1,5a,6,7,8,9aα-Hexahydro-6β-(1-methylethyl)-1-oxospiro[2-benzoxepine-9(3H),2'-oxirane]-4-carboxylic acid

(5aS,9S)-1,5aβ,6,7,8,9aα-Hexahydro-6β-isopropyl-1-oxospiro[2-benzoxepine-9(3H),2'-oxirane]-4-carboxylic acid

Avocettin

Koningic acid

Spiro[2-benzoxepin-9(3H),2'-oxirane]-4-carboxylic acid, 1,5a,6,7,8,9a-hexahydro-6-(1-methylethyl)-1-oxo-, (2'S,5aS,6R,9aS)-

57710-57-3