3-MORPHOLIN-4-YLMETHYLBENZOIC ACID
- Product Name
- 3-MORPHOLIN-4-YLMETHYLBENZOIC ACID
- CAS No.
- 67451-81-4
- Chemical Name
- 3-MORPHOLIN-4-YLMETHYLBENZOIC ACID
- Synonyms
- AKOS BB-9413;3-(Morpholinomethyl);3-(Morpholinomethyl)benzoic Acid;3-MORPHOLIN-4-YLMETHYLBENZOIC ACID;3-(4-Morpholinylmethyl)Benzoic acid;3-Morpholin-4-ylmethylbenzoicacid95%;Benzoic acid, 3-(4-morpholinylmethyl)-;3-MORPHOLIN-4-YLMETHYLBENZOIC ACID 95%
- CBNumber
- CB2145934
- Molecular Formula
- C12H15NO3
- Formula Weight
- 221.25
- MOL File
- 67451-81-4.mol
3-MORPHOLIN-4-YLMETHYLBENZOIC ACID Property
- Boiling point:
- 376.9±32.0 °C(Predicted)
- Density
- 1.233±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 3.98±0.10(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- M732740
- Product name
- 3-(Morpholinomethyl)benzoicAcid
- Packaging
- 500mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- 071860
- Product name
- 3-Morpholin-4-ylmethylbenzoic acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $347
- Updated
- 2021/12/16
- Product number
- COR0002485
- Product name
- 3-MORPHOLIN-4-YLMETHYLBENZOIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $258.3
- Updated
- 2021/12/16
- Product number
- 071860
- Product name
- 3-Morpholin-4-ylmethylbenzoic acid
- Purity
- 95+%
- Packaging
- 5g
- Price
- $998
- Updated
- 2021/12/16
- Product number
- 071860
- Product name
- 3-Morpholin-4-ylmethylbenzoic acid
- Purity
- 95+%
- Packaging
- 10g
- Price
- $1519
- Updated
- 2021/12/16
3-MORPHOLIN-4-YLMETHYLBENZOIC ACID Chemical Properties,Usage,Production
Synthesis
190660-95-8
67451-81-4
General procedure for the synthesis of 3-morpholin-4-ylmethylbenzoic acid from methyl 3-(4-morpholinylmethyl)benzoate: to a solution of methyl 3-(4-morpholinylmethyl)benzoate (5.02 g, 21.0 mmol) in methanol (100 mL) was added a sodium hydroxide solution (21.0 mL, 42.0 mmol, 2M). The reaction mixture was heated at 50 °C with stirring for 16 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was adjusted to pH=3 with 1M hydrochloric acid and the resulting suspension was subsequently filtered. The collected solid was dissolved in acetonitrile (15 mL) and concentrated to afford 3-(morpholin-4-ylmethyl)benzoic acid (4.6 g, 100% yield) as a white solid, which was used directly in the subsequent reaction without further purification.
References
[1] Patent: WO2018/169777, 2018, A1. Location in patent: Paragraph 0229
3-MORPHOLIN-4-YLMETHYLBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
3-MORPHOLIN-4-YLMETHYLBENZOIC ACID Suppliers
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