5-Chloro-2-iodopyrimidine
- Product Name
- 5-Chloro-2-iodopyrimidine
- CAS No.
- 874676-81-0
- Chemical Name
- 5-Chloro-2-iodopyrimidine
- Synonyms
- 5-Chloro-2-iodopyrimidine;Pyrimidine, 5-chloro-2-iodo-;5-Chloro-2-iodopyrimidine 97%;5-Chloro-2-iodopyrimidine ISO 9001：2015 REACH
- CBNumber
- CB21483439
- Molecular Formula
- C4H2ClIN2
- Formula Weight
- 240.43
- MOL File
- 874676-81-0.mol
5-Chloro-2-iodopyrimidine Property
- Boiling point:
- 316.6±34.0 °C(Predicted)
- Density
- 2.187±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- pka
- -2.56±0.22(Predicted)
- form
- Powder
- color
- White
- Water Solubility
- Slightly soluble in water.
- Sensitive
- Light Sensitive
- InChI
- InChI=1S/C4H2ClIN2/c5-3-1-7-4(6)8-2-3/h1-2H
- InChIKey
- BWDLBDLGVMLSCS-UHFFFAOYSA-N
- SMILES
- C1(I)=NC=C(Cl)C=N1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- SYX00017
- Product name
- 5-Chloro-2-iodopyrimidine
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $174
- Updated
- 2024/03/01
- Product number
- H64185
- Product name
- 5-Chloro-2-iodopyrimidine, 98%
- Packaging
- 1g
- Price
- $52.4
- Updated
- 2021/12/16
- Product number
- H64185
- Product name
- 5-Chloro-2-iodopyrimidine, 98%
- Packaging
- 5g
- Price
- $208
- Updated
- 2021/12/16
- Product number
- H64185
- Product name
- 5-Chloro-2-iodopyrimidine, 98%
- Packaging
- 250mg
- Price
- $17.8
- Updated
- 2021/12/16
- Product number
- C381668
- Product name
- 5-Chloro-2-iodopyrimidine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
5-Chloro-2-iodopyrimidine Chemical Properties,Usage,Production
Description
5-Chloro-2-iodopyrimidine is an organic molecule that belongs to the class of trifluoromethylated molecules. It is a halogenated derivative of pyrimidine and has a molecular formula of C4H2ClIN2. 5-Chloro-2-iodopyrimidine can be catalyzed with copper, which is responsible for its unique reactivity. The synthesis of this molecule has been shown to be efficient in organic chemistry.
Uses
Useful Intermediate for organic synthesis and pharmaceutical.
Preparation
A flask was charged with 57% HI (48 ml) and then cooled to 0°C in an ice-salt mixture. Dichloropyrimidine (6 g) was added to the mixture. After 4h, the obtained yellow suspension was treated carefully with K2CO3 solution (32 g, 60 ml), and the pale yellow solid was collected by filtration. The solid was washed with water and dried to give compound 5-Chloro-2-iodopyrimidine.
Application
As a chemical intermediate used in the pharmaceutical and agrochemical industriesIt, 5-Chloro-2-iodopyrimidine is commonly used as a building block in the synthesis of biologically active molecules, such as kinase inhibitors, antiviral agents, and herbicides.
Origin
5-Chloro-2-iodopyrimidine was discovered by chemists in 2006 and has been used as a reagent for the efficient trifluoromethylation of organic molecules.
5-Chloro-2-iodopyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Chloro-2-iodopyrimidine manufacturers
- Product
- 5-Chloro-2-iodopyrimidine 874676-81-0
- Price
- US $36.00-1.10/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08
- Product
- 5-Chloro-2-iodopyrimidine 874676-81-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-06
- Product
- 5-Chloro-2-iodopyrimidine 874676-81-0
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-09