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QUININE

Product Name
QUININE
CAS No.
511-98-8
Chemical Name
QUININE
Synonyms
Soladulcidine;Dihydrosolasodine;(22R,25R)-5α-Spirosolane-3β-ol;Spirosolan-3-ol, (3β,5α,22α,25R)-;(2aS,2'R,4S,5'R,6aS,6bS,8aS,8bR,9S,11aS,12aS,12bR)-5',6a,8a,9-tetramethyloctadecahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-piperidin]-4-ol
CBNumber
CB21484340
Molecular Formula
C27H45NO2
Formula Weight
415.65
MOL File
511-98-8.mol
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QUININE Property

Melting point:
209- 211°C
Boiling point:
527.2±25.0 °C(Predicted)
Density 
1.10±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Methanol (Slightly, Heated)
form 
Solid
pka
15.14±0.70(Predicted)
color 
Pale Brown
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FS65471
Product name
Soladulcidine tetraoside
Packaging
1mg
Price
$350
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS65471
Product name
Soladulcidine tetraoside
Packaging
2mg
Price
$500
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS65471
Product name
Soladulcidine tetraoside
Packaging
5mg
Price
$950
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS65471
Product name
Soladulcidine tetraoside
Packaging
10mg
Price
$1250
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS65471
Product name
Soladulcidine tetraoside
Packaging
25mg
Price
$2650
Updated
2021/12/16
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QUININE Chemical Properties,Usage,Production

Description

This alkaloid from Solanum dulcamara forms colourless plates when crystallized from MeOH. It is laevorotatory with [α]D - 50° (c 0.4, CHCI3). The alkaloid forms the O,N-diformyl derivative which exists as two rotational isomers, the trans with m.p. 222-4°C; [α]20D - 21.2° (CHCI3) and the cis isomer with m.p. 202-4°C; [α]20D - 69.6° (CHCI3).

Uses

Soladulcidine is a steroidal glycoalkaloid extracted from tomato leaves and berries and can induce craniofacial malformations in hamsters.

Definition

ChEBI: Soladulcidine is an azaspiro compound, a steroid and an oxaspiro compound.

References

Schreiber., Planta Med., 6,93 (1958)
Alkemeyer, Sandor., Naturwiss., 46, 207 (1959)
Schreiber, Adam., Experientia, 17,13 (1961)
Schreiber, Adam., Annalen, 666, 155 (1963)
Synthesis:
Adam, Schreiber., Experientia, 21,471 (1965)
Adam, Schreiber., Tetrahedron, 22, 3591 (1966)
Absolute configuration:
Boll, von Philipsborn., Acta Chem. Scand., 19,1365 (1965)

QUININE Preparation Products And Raw materials

Raw materials

Preparation Products

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QUININE Suppliers

Interbioscreen Ltd.
Tel
--
Fax
--
Email
screen@ibscreen.chg.ru
Country
Finland
ProdList
6176
Advantage
60

511-98-8, QUININERelated Search:


  • (22R,25R)-5α-Spirosolane-3β-ol
  • Dihydrosolasodine
  • Soladulcidine
  • (2aS,2'R,4S,5'R,6aS,6bS,8aS,8bR,9S,11aS,12aS,12bR)-5',6a,8a,9-tetramethyloctadecahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-piperidin]-4-ol
  • Spirosolan-3-ol, (3β,5α,22α,25R)-
  • 511-98-8
  • Alkaloids