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4,4'-DIACETAMIDODIPHENYLMETHANE

Product Name
4,4'-DIACETAMIDODIPHENYLMETHANE
CAS No.
2719-05-3
Chemical Name
4,4'-DIACETAMIDODIPHENYLMETHANE
Synonyms
NSC 12407;BRD-K4477;FH1(BRD-K4477);N,N'-AcetylMDA;FH1 >=98% (HPLC);4,4'-DIACETAMIDODIPHENYLMETHANE;4,4'-diacetamidodiphenylmethane;4,4''-DIACETAMIDODIPHENYLMETHANE 98%;N-[4-(4-acetamidobenzyl)phenyl]acetamide;N,N′-(Methylenedi-4,1-phenylene)diacetamide
CBNumber
CB2149684
Molecular Formula
C17H18N2O2
Formula Weight
282.34
MOL File
2719-05-3.mol
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4,4'-DIACETAMIDODIPHENYLMETHANE Property

Melting point:
227-228 °C
Boiling point:
564.6±43.0 °C(Predicted)
Density 
1.201±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
Soluble in DMSO (up to 30 mg/ml)
form 
solid
pka
14.73±0.70(Predicted)
color 
White
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
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Safety

Hazard Codes 
N
Risk Statements 
50/53
Safety Statements 
60-61
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0826
Product name
FH1
Purity
≥98% (HPLC)
Packaging
5MG
Price
$75.6
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0826
Product name
FH1
Purity
≥98% (HPLC)
Packaging
25MG
Price
$300
Updated
2024/03/01
Sigma-Aldrich
Product number
S685682
Product name
4'',4''''-METHYLENEBIS(ACETANILIDE)
Purity
AldrichCPR
Packaging
250MG
Price
$41.5
Updated
2024/03/01
Cayman Chemical
Product number
18415
Product name
BRD-K4477
Purity
≥98%
Packaging
5mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
18415
Product name
BRD-K4477
Purity
≥98%
Packaging
10mg
Price
$87
Updated
2024/03/01
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4,4'-DIACETAMIDODIPHENYLMETHANE Chemical Properties,Usage,Production

Description

FH-1 (2719-05-3) enhances differentiation of induced pluripotent stem cells (iPSC) to hepatocytes. Promotes the maturation of iPSC-derived hepatocytes.

Uses

FH 1 is used as an inducer of cell proliferations (i.e. inducing proliferation and differentiation of stem cells for formation of hepatocytes for treatment of liver disease).

storage

+4°C

References

1) Shan?et al. (2013),?Identification of small molecules for human hepatocyte expansion and iPS differentiation; Nat. Chem. Biol., 9 514

4,4'-DIACETAMIDODIPHENYLMETHANE Preparation Products And Raw materials

Raw materials

Preparation Products

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4,4'-DIACETAMIDODIPHENYLMETHANE Suppliers

China 60 Germany 1 United Kingdom 4 United States 12 Global 77

2719-05-3, 4,4'-DIACETAMIDODIPHENYLMETHANERelated Search:

4,4'-DIACETAMIDODIPHENYLMETHANE 4,4',4''-TRIS(4,5-DICHLOROPHTHALIMIDO)TRITYL BROMIDE Diphenylmethane Bismaleimide BIS(3-ETHYL-5-METHYL-4-MALEIMIDOPHENYL)METHANE N-(4-(9-[4-(3-CARBOXY-PROPIONYLAMINO)-PHENYL]-9H-FLUOREN-9-YL)-PHENYL)-SUCCINAMIC ACID BIO-FARMA BF003995 N-(4-[4-(3-CARBOXY-PROPIONYLAMINO)-BENZYL]-PHENYL)-SUCCINAMIC ACID RHODAMINE 110, BIS-(N-CBZ-L-ALANYL-L-ALANYL-L- ASPARTIC ACID AMIDE) N,N'-(methylenedi-p-phenylene)bis[3,4,5,6,-tetrabromophthalimide] 2-(1-PYRROLIDINYL)-N-[4-(4-([2-(1-PYRROLIDINYL)ACETYL]AMINO)BENZYL)PHENYL]ACETAMIDE 2-PIPERIDINO-N-(4-(4-[(2-PIPERIDINOACETYL)AMINO]BENZYL)PHENYL)ACETAMIDE 2-MORPHOLINO-N-(4-(4-[(2-MORPHOLINOACETYL)AMINO]BENZYL)PHENYL)ACETAMIDE N,N'-(4,4'-METHYLENEBIS(2-METHOXY-4,1-PHENYLENE))DITHIOPHENE-2-CARBOXAMIDE RHODAMINE 110, BIS-(N-CBZ-L-LEUCYL-L-GLUTAMYL-L- GLUTAMYL-L-ASPARTIC ACID AMIDE) RHODAMINE 110, BIS-(N-CBZ-L-LEUCYL-L-GLUTAMYL-L- HISTIDINYL-L-ASPARTIC ACID AMIDE) VITAS-BB TBB000597 RHODAMINE 110, BIS-(N-CBZ-L-VALYL-L-GLUTAMYL-L- ISOLEUCYL-L-ASPARTIC ACID AMIDE)

  • 4,4'-DIACETAMIDODIPHENYLMETHANE
  • N-[4-(4-acetamidobenzyl)phenyl]acetamide
  • N-[4-[(4-acetamidophenyl)methyl]phenyl]acetamide
  • N-[4-[(4-acetamidophenyl)methyl]phenyl]ethanamide
  • N,N'-(4,4'-Methylenebis(4,1-phenylene))diacetaMide
  • FH1(BRD-K4477)
  • Acetamide,N,N'-(methylenedi-4,1-phenylene)bis-
  • BRD-K4477
  • N,N′-(Methylenedi-4,1-phenylene)bis-acetamide
  • N,N′-(Methylenedi-4,1-phenylene)diacetamide
  • NSC 12407
  • N,N-Acetyl MDA~Bis(4-acetamidophenyl)methane~4,4-Methylenedibenzamide
  • Bis(4-acetamidophenyl)methane~4,4'-Methylenedibenzamide
  • N,N'-AcetylMDA
  • 4,4''-DIACETAMIDODIPHENYLMETHANE 98%
  • NSC 12407; BRD-K4477; FH 1; NSC12407; BRDK4477
  • FH1 >=98% (HPLC)
  • N,N'-(Methylenebis(4,1-phenylene))diacetamide
  • hHNF4α,IPS,hALB,iPSC,FH1,FH-1,inhibit,Inhibitor,hNTCP,NSC12407,NSC-12407,hRXR,FH 1
  • 4,4'-diacetamidodiphenylmethane
  • N,N'-(Methylenebis(4,1-phenylene))diacetamide
  • 2719-05-3
  • Inhibitors