STIRIPENTOL
- Product Name
- STIRIPENTOL
- CAS No.
- 49763-96-4
- Chemical Name
- STIRIPENTOL
- Synonyms
- Diacomit;bcx2600;RCX-2600;Slipperto;STIRIPENTOL;Stiripentol >BCX2600|||Diacomit;Stiripentol, ≥ 98.0%;Stiripentol(BCX 2600);STIRIPENTOL USP/EP/BP
- CBNumber
- CB2150457
- Molecular Formula
- C14H18O3
- Formula Weight
- 234.29
- MOL File
- 49763-96-4.mol
STIRIPENTOL Property
- Melting point:
- 73-74°C
- Boiling point:
- 365.4±11.0 °C(Predicted)
- Density
- 1.139±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO: ≥20mg/mL
- pka
- 14.45±0.20(Predicted)
- form
- powder
- color
- white to beige
- InChIKey
- IBLNKMRFIPWSOY-FNORWQNLSA-N
- CAS DataBase Reference
- 49763-96-4
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- S6826
- Product name
- Stiripentol
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $87.5
- Updated
- 2024/03/01
- Product number
- S6826
- Product name
- Stiripentol
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $354
- Updated
- 2024/03/01
- Product number
- S0905
- Product name
- Stiripentol
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $245
- Updated
- 2024/03/01
- Product number
- S0905
- Product name
- Stiripentol
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $846
- Updated
- 2024/03/01
- Product number
- 17781
- Product name
- Stiripentol
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $68
- Updated
- 2024/03/01
STIRIPENTOL Chemical Properties,Usage,Production
Description
Stiripentol is a third-generation antiepileptic compound. It is a positive allosteric modulator of GABAA receptors, potentiating GABA-mediated activation to a greater extent in receptors expressing α3 subunits and to a lower extent in those containing β1 or ε subunits. It also inhibits GABA reuptake in vitro and increases the release of GABA in neonatal rat hippocampal slices. Stiripentol (500 μM) inhibits lactate dehydrogenase (LDH), blocking both lactate-to-pyruvate and pyruvate-to-lactate conversions by human LDH1 and LDH5. Formulations containing stiripentol have been used in the adjunctive treatment of seizures associated with Dravet syndrome.
Chemical Properties
White Solid
Uses
An antiepileptic drug
Uses
Stiripentol has been used in pharmacokinetic analysis and as a reference standard in fluorescence spectra analysis.
Uses
Stiripentol is an epilepsy drug, it has been used as co-therapy for treatment of epilepsy.
Definition
ChEBI: 1-(1,3-benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-ol is a phenylpropanoid.
Biochem/physiol Actions
Anti-convulsant drug
STIRIPENTOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from STIRIPENTOL manufacturers
- Product
- STIRIPENTOL 49763-96-4
- Price
- US $714.30/Kg/Bag
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500kg
- Release date
- 2021-06-02
- Product
- STIRIPENTOL 49763-96-4
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-17
- Product
- Stiripentol 49763-96-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-26