ChemicalBook > CAS DataBase List > 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid

2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid

Product Name
2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid
CAS No.
391211-97-5
Chemical Name
2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid
Synonyms
2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid;3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzoic acid;2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic acid 98%;3,4-Difluoro-2-(2-fluoro-4-iodophenylaMino)benzoic Acid;3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)aMino]benzoic Acid;Benzoic acid, 3,4-difluoro-2-[(2-fluoro-4-iodophenyl)aMino]-;2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID
CBNumber
CB21507957
Molecular Formula
C13H7F3INO2
Formula Weight
393.1
MOL File
391211-97-5.mol
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2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid Property

Melting point:
189-191°C
Boiling point:
370.1±42.0 °C(Predicted)
Density 
1.939±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
DMSO (Sparingly), Methanol (Slightly)
form 
Solid
pka
3.25±0.36(Predicted)
color 
Off-White to Beige
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Safety

HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
F591960
Product name
2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoicAcid
Packaging
2g
Price
$315
Updated
2021/12/16
Matrix Scientific
Product number
099339
Product name
3,4-Difluoro-2-((2-fluoro-4-iodophenyl)-amino)benzoic acid
Purity
95+%
Packaging
1g
Price
$353
Updated
2021/12/16
Apolloscientific
Product number
PC408065
Product name
2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoicacid
Purity
98%
Packaging
1g
Price
$286
Updated
2021/12/16
SynQuest Laboratories
Product number
4657-K-01
Product name
3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzoic acid
Packaging
1g
Price
$295
Updated
2021/12/16
AK Scientific
Product number
5091AB
Product name
3,4-Difluoro-2-((2-fluoro-4-iodophenyl)amino)benzoicacid
Packaging
5g
Price
$752
Updated
2021/12/16
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2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Intermediate in the preparation of MEK inhibitors.

Synthesis

To a solution of methyl-3,4-diflluoro-2-((2-flluoro-4-iodophenyl)amino)benzoate (23, 6.0 g, 23.8 mmol) in methanol (80 mL) and water (80 mL) was added LiOH (7.8 g, 195 mmol). The reaction mixture was stirred at 78 C in an oil bath for 1 h. After cooling, the reaction mixture was acidified to pH = 2 with a 2 N HCl solution. The solid was filtered and washed with water to provide 2-(2-Fluoro-4-iodoanilino)-3,4-difluoro benzoic Acid (5.11 g, 96%) as a white solid.

2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid Suppliers

Canada 1 China 81 India 2 United Kingdom 1 United States 7 Global 92
Yangzhou QinYuan Pharmaceutical Co., Ltd.
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0514-80939770 13773367191
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010-82848833 400-666-7788
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86-10-82849933
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View Lastest Price from 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid manufacturers

Career Henan Chemical Co
Product
2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID 391211-97-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20kg
Release date
2018-08-13

391211-97-5, 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic AcidRelated Search:

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  • 3,4-Difluoro-2-(2-fluoro-4-iodophenylaMino)benzoic Acid
  • 3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)aMino]benzoic Acid
  • Benzoic acid, 3,4-difluoro-2-[(2-fluoro-4-iodophenyl)aMino]-
  • 3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzoic acid
  • 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic acid 98%
  • 391211-97-5
  • C13H7F3INO2
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  • Pharmaceuticals