ChemicalBook > CAS DataBase List > 2-Chloro-4-methylquinazoline

2-Chloro-4-methylquinazoline

Product Name
2-Chloro-4-methylquinazoline
CAS No.
6141-14-6
Chemical Name
2-Chloro-4-methylquinazoline
Synonyms
2-Chloro-4-methylquinazoline;Quinazoline, 2-chloro-4-methyl-
CBNumber
CB21512485
Molecular Formula
C9H7ClN2
Formula Weight
178.62
MOL File
6141-14-6.mol
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2-Chloro-4-methylquinazoline Property

Boiling point:
262.8±23.0 °C(Predicted)
Density 
1.292±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
0.94±0.30(Predicted)
Appearance
White to yellow Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C368945
Product name
2-Chloro-4-methylquinazoline
Packaging
2.5mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC140830
Product name
2-Chloro-4-methylquinazoline
Packaging
10mg
Price
$65
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC140830
Product name
2-Chloro-4-methylquinazoline
Packaging
25mg
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC140830
Product name
2-Chloro-4-methylquinazoline
Packaging
50mg
Price
$150
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC140830
Product name
2-Chloro-4-methylquinazoline
Packaging
100mg
Price
$220
Updated
2021/12/16
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2-Chloro-4-methylquinazoline Chemical Properties,Usage,Production

Synthesis

34790-24-4

6141-14-6

2-Chloro-4-methylquinazoline was prepared by reacting 4-methylquinazolin-2(3H)-one as starting material in the presence of phosphorus trichloride and hydrochloric acid, referring to the method of Example 27c. The reaction yield was 67% of the theoretical value, and the product was detected by thin layer chromatography (silica gel plate, unfolding agent was petroleum ether/ethyl acetate=7:3) with an Rf value of 0.81.

References

[1] Patent: US6200976, 2001, B1
[2] Chemical Communications, 2014, vol. 50, # 33, p. 4302 - 4304
[3] Patent: WO2005/123714, 2005, A1. Location in patent: Page/Page column 7

2-Chloro-4-methylquinazoline Preparation Products And Raw materials

Raw materials

Preparation Products

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6141-14-6, 2-Chloro-4-methylquinazolineRelated Search:

2-chloro-6-Methylquinazoline 2-Chloroquinazoline-4-carbaldehyde 2,6-DICHLORO-4-PHENYL-QUINAZOLINE 2-CHLORO-4-PHENYLQUINAZOLINE 2-chloro-4-(4-chlorophenyl)quinazoline 2-Chloro-4-methylquinazoline SPECS AQ-917/42754106 6-BROMO-2-CHLORO-4-METHYLQUINAZOLINE 2-CHLORO-6-METHYL-4-PHENYL-QUINAZOLINE 6-BROMO-2-CHLORO-4-PHENYLQUINAZOLINE

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  • 6141-14-6
  • API intermediates