PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE

Product Name: PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE
CAS No.: 21038-67-5
Chemical Name: PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE
Synonyms: pyrido[3,4-d]pyriMidine-2,4-diol;1H-pyrido[3,4-d]pyrimidine-2,4-dione;2,4-Dihydroxypyrido[3,4-d]pyrimidine;PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE;Pyrido[3,4-d]pyrimidine-2,4(1h,3h)-dione 95%;1H,2H,3H,4H-pyrido[2,3-d]pyriMidine-2,4-dione;1H,2H,3H,4H-Pyrido[3,4-d]pyrimidine-2,4-dione;Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione - [P71315]
CBNumber: CB2156196
Molecular Formula: C7H5N3O2
Formula Weight: 163.13
MOL File: 21038-67-5.mol

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PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE Property

Melting point:: >320 °C
Density: 1.424±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 9.01±0.20(Predicted)
Appearance: Off-white to gray Solid

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: P997305
Product name: Pyrido[3,4-D]pyrimidine-2,4(1H,3H)-dione
Packaging: 100mg
Price: $110
Updated: 2021/12/16

BroadPharm

Product number: BP-20262
Product name: pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione
Purity: 95%
Packaging: 1g
Price: $100
Updated: 2021/12/16

BroadPharm

Product number: BP-20263
Product name: pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione
Purity: 96%
Packaging: 500mg
Price: $145
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H53-1-49
Product name: 1H,2H,3H,4H-Pyrido[3,4-d]pyrimidine-2,4-dione
Packaging: 250mg
Price: $240
Updated: 2021/12/16

BroadPharm

Product number: BP-20263
Product name: pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione
Purity: 96%
Packaging: 1g
Price: $250
Updated: 2021/12/16

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PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE Chemical Properties,Usage,Production

Synthesis

64188-97-2

32315-10-9

21038-67-5

To a solution of 3-aminopyridine-4-carboxamide (5 g, 36.5 mmol) in tetrahydrofuran (THF, 100 mL) was sequentially added triphosgene (11.9 g, 40.1 mmol) and triethylamine (TEA, 7.4 g, 73 mmol). The reaction mixture was heated to reflux for 2 hours. After completion of the reaction, the solution was concentrated under reduced pressure and the residue was ground with an appropriate amount of water. The solid product was collected by filtration and washed sequentially with water and THF. The solid was dried to give pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione 4.1 g in 70% yield. The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 11.62 (s, 1H), 11.58 (s, 1H), 8.66 (s, 1H), 8.40 (d, 1H, J = 5.2 Hz), 7.80 (d, 1H, J = 5.2 Hz).

References

[1] Patent: WO2014/151106, 2014, A1. Location in patent: Paragraph 00108
[2] Patent: WO2016/44429, 2016, A1. Location in patent: Paragraph 00154; 00155

PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE Suppliers

China 60 Germany 2 India 1 Switzerland 1 United Kingdom 1 United States 7 Global 72

Capot Chemical Co., Ltd

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Synchem OHG

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View Lastest Price from PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE manufacturers

Career Henan Chemical Co

Product: PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE 21038-67-5
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2020-02-05

21038-67-5, PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONERelated Search:

pyrido[2,3-b]pyrazin-2(1H)-one PYRIDO[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE Pyrido[4,3-d]pyrimidin-5(6H)-one (9CI) PYRROLO[1,2-A]QUINOXALIN-4(5H)-ONE 4-AMINOMETHYL-PYRIDIN-3-YLAMINE PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE 3-AMINO-4-PYRIDINECARBOXAMIDE pyrido[3,4-b]pyrazin-5-ylmethanamine pyrido[4,3-d]pyrimidin-4-amine Pyrido[4,3-d]pyriMidine-2,4(1H,3H)-dione Pyrido[4,3-d]pyrimidine-2,4-diamine PYRIDO[3,2-D]PYRIMIDIN-4-AMINE Pyrido[3,2-d]pyrimidine-2,4-diamine pyrido[3,4-b]pyrazine-5-carboxylic acid pyrido[3,4-b]pyrazine-5-carbonitrile pyrido[3,4-d]pyrimidine-2,4-diamine Pyrido[3,2-d]pyrimidine-2,4(1H,3H)-dione pyrido[3,2-d]pyrimidin-2-amine

PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE

1H,2H,3H,4H-pyrido[2,3-d]pyriMidine-2,4-dione

pyrido[3,4-d]pyriMidine-2,4-diol

2,4-Dihydroxypyrido[3,4-d]pyrimidine

1H-pyrido[3,4-d]pyrimidine-2,4-dione

1H,2H,3H,4H-Pyrido[3,4-d]pyrimidine-2,4-dione

Pyrido[3,4-d]pyrimidine-2,4(1h,3h)-dione 95%

Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione - [P71315]

21038-67-5

Heterocycle-Pyrimidine series