3-AMINO-4-PYRIDINECARBOXAMIDE

Product Name: 3-AMINO-4-PYRIDINECARBOXAMIDE
CAS No.: 64188-97-2
Chemical Name: 3-AMINO-4-PYRIDINECARBOXAMIDE
Synonyms: 3-Amino-isonicotimide;3-AMINOISONICOTINAMIDE;Olutasidenib Impurity 31;3-aMino-4-carbaMoylpyridine;3-Aminopyridin-4-carboxamide;3-AMINO-4-PYRIDINECARBOXAMIDE;3-Aminoisopyridin-3-carboxamide;4-Pyridinecarboxamide, 3-amino-;methyl 3-aminoisonicotinate (en);4-Pyridinecarboxamide,3-amino-(9CI)
CBNumber: CB9696536
Molecular Formula: C6H7N3O
Formula Weight: 137.14
MOL File: 64188-97-2.mol

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3-AMINO-4-PYRIDINECARBOXAMIDE Property

Melting point:: 84-86°
Boiling point:: 369.2±22.0 °C(Predicted)
Density: 1.323±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 14.73±0.50(Predicted)
Appearance: Off-white to light yellow Solid

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Safety

Hazard Codes: Xi
HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AstaTech

Product number: CL0131
Product name: 3-AMINOISONICOTINAMIDE
Purity: 97%
Packaging: 1G
Price: $38
Updated: 2026/04/30

AstaTech

Product number: CL0131
Product name: 3-AMINOISONICOTINAMIDE
Purity: 97%
Packaging: 5G
Price: $150
Updated: 2026/04/30

AstaTech

Product number: CL0131
Product name: 3-AMINOISONICOTINAMIDE
Purity: 97%
Packaging: 25G
Price: $505
Updated: 2026/04/30

Chem-Impex

Product number: 26244
Product name: 3-Aminopyridine-4-carboxamide
Purity: ≥95%(HPLC)
Packaging: 100MG
Price: $96.34
Updated: 2026/05/19

Chem-Impex

Product number: 26244
Product name: 3-Aminopyridine-4-carboxamide
Purity: ≥95%(HPLC)
Packaging: 250MG
Price: $180.27
Updated: 2026/05/19

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3-AMINO-4-PYRIDINECARBOXAMIDE Chemical Properties,Usage,Production

Synthesis

7579-20-6

64188-97-2

General procedure for the synthesis of 3-aminoisonicotinamide from 3-aminoisonicotinic acid: ammonium hydrochloride (4.98 g, 93.2 mmol) was mixed with 3-aminoisonicotinic acid (9.90 g, 71.7 mmol) to which was added 2-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)-1 ,1,3,3-tetramethylene diuronium hexafluorophosphate (V) ( 35.4 g, 93.2 mmol) and N-ethyl-N-isopropylpropan-2-amine (37.5 mL, 215.02 mmol) in a solution of DMF (100 mL). The reaction mixture was stirred at 40 °C for 72 h under nitrogen protection. After completion of the reaction, the solvent was removed by evaporation to give the crude product. The crude product was purified by fast silica gel column chromatography using a gradient elution with a dichloromethane solution of 5% methanol. The purified grades were collected and evaporated to dryness to give 3-aminoisonicotinamide (8.57 g, 87% yield) as a yellow gel.

References

[1] Synthesis (Germany), 2016, vol. 48, # 8, p. 1226 - 1234
[2] Bioorganic and Medicinal Chemistry, 2011, vol. 19, # 5, p. 1623 - 1642
[3] Patent: WO2013/12915, 2013, A1. Location in patent: Paragraph 00674-00676
[4] European Journal of Medicinal Chemistry, 2018, vol. 152, p. 235 - 252
[5] Patent: WO2007/117161, 2007, A1. Location in patent: Page/Page column 24-25

3-AMINO-4-PYRIDINECARBOXAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-AMINO-4-PYRIDINECARBOXAMIDE Suppliers

China 86 Czech Republic 1 Europe 1 Germany 1 India 1 United Kingdom 3 United States 7 Global 100

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View Lastest Price from 3-AMINO-4-PYRIDINECARBOXAMIDE manufacturers

Career Henan Chemical Co

Product: 3-AMINO-4-PYRIDINECARBOXAMIDE 64188-97-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%
Supply Ability: 500KG
Release date: 2018-08-19

64188-97-2, 3-AMINO-4-PYRIDINECARBOXAMIDERelated Search:

N(2,6 Dichloro-4 Methyl-3-Pyridyl-2-Cyclopropyl Amino)-3-Pyridinecarboxamide 5-AMINO-3-PYRIDINECARBOXAMIDE N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide 4-AMINO-3-PYRIDINECARBOXAMIDE 2-Amino-3-pyridinecarboxamide 6-AMINO-3-PYRIDINECARBOXAMIDE 1-[(2,3-DIAMINO-4-PYRIDINYL)CARBONYL]-PIPERIDINE 3-Amino-N-(2,4,6-trimethylphenyl)-4-pyridinecarboxamide 3-AMINO-4-PYRIDINECARBOXAMIDE 3-AMINO-2-CHLORO-ISONICOTINAMIDE PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE 2-ETHYLPYRIDO[3,4-D]PYRIMIDIN-4(1H)-ONE 2,3-DIHYDRO-2-THIOXO-PYRIDO[3,4-D]PYRIMIDIN-4(1H)-ONE 3-NITRO-4-PYRIDINECARBOXAMIDE

3-Amino-isonicotimide

3-AMINOISONICOTINAMIDE

3-AMINO-4-PYRIDINECARBOXAMIDE

4-Pyridinecarboxamide,3-amino-(9CI)

methyl 3-aminoisonicotinate (en)

3-aMino-4-carbaMoylpyridine

3-amino(38C5,38N)pyridine-4-carboxamide

4-Pyridinecarboxamide, 3-amino-

3-Aminopyridin-4-carboxamide

Olutasidenib Impurity 31

3-Aminoisopyridin-3-carboxamide

64188-97-2

AMIDE

Pyridines

Pyridine