ChemicalBook > CAS DataBase List > Motesanib

Motesanib

Product Name
Motesanib
CAS No.
453562-69-1
Chemical Name
Motesanib
Synonyms
D06678;CS-1108;motesanib;Motesanib Base;AMG 706; AMG-706;AMG-706(Motesanib);Motesanib (AMG-706) Base);2,4-Imidazolidinedione,5-(3-bromophenyl)-6-methyl-;N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide;N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide,AMG706
CBNumber
CB01518524
Molecular Formula
C22H23N5O
Formula Weight
373.45
MOL File
453562-69-1.mol
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Motesanib Property

Melting point:
147-150°C
Boiling point:
517.3±50.0 °C(Predicted)
Density 
1.251
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
White powder solid.
pka
11.75±0.40(Predicted)
color 
Pale Yellow
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M732500
Product name
Motesanib
Packaging
50mg
Price
$165
Updated
2021/12/16
Usbiological
Product number
017881
Product name
Motesanib
Packaging
5mg
Price
$496
Updated
2021/12/16
Adipogen Life Sciences
Product number
SYN-1055-M100
Product name
Motesanib
Purity
≥95%
Packaging
100mg
Price
$1069
Updated
2021/12/16
AK Scientific
Product number
X4931
Product name
Motesanib
Packaging
500mg
Price
$1265
Updated
2021/12/16
Matrix Scientific
Product number
132644
Product name
N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide
Purity
97%
Packaging
250mg
Price
$630
Updated
2021/12/16
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Motesanib Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3, PDGFR, c-Kit and Ret with IC50 of 2 nM/3 nM/6 nM, 84 nM, 8 nM and 59 nM, respectively.

Uses

Motesanib is an oral angiogenesis inhibitor, demonstrates clinical efficacy in advanced thymoma.

Definition

ChEBI: Motesanib is a pyridinecarboxamide.

target

VEGFR1

Motesanib Preparation Products And Raw materials

Raw materials

Preparation Products

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Motesanib Suppliers

Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
3351
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
ZHIWE CHEMTECH CO LTD
Tel
021-20221225 13917446399
Fax
QQ:115820162
Email
sales@zhiwe.net
Country
China
ProdList
579
Advantage
61
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6013
Advantage
61
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2127
Advantage
70
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Jinan Trio PharmaTech Co., Ltd.
Tel
+86 (531) 88811783
Fax
+86 (531) 55696010 QQ 1762738062
Email
sales@trio-pharmatech.com (International market)
Country
China
ProdList
1856
Advantage
62
Xi’an chemsoar Medical Technology Co., ltd
Tel
029-86538357
Fax
029-87871708
Country
China
ProdList
234
Advantage
57
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4647
Advantage
58
Beijing Yisiyan Technology Research Center
Tel
010-56645598 13366904824
Fax
01062230033
Email
bjkaida@163.com
Country
China
ProdList
1669
Advantage
59
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View Lastest Price from Motesanib manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
motesanib 453562-69-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-26
Career Henan Chemical Co
Product
Motesanib 453562-69-1
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
100kgs
Release date
2020-01-02

453562-69-1, MotesanibRelated Search:


  • CS-1108
  • AMG 706; AMG-706
  • N-(3,3-diMethylindolin-6-yl){2-[(4-pyridylMethyl)-aMino](3-pyridyl)}-carboxaMide
  • 3-PyridinecarboxaMide, N-(2,3-dihydro-3,3-diMethyl-1H-indol-6-yl)-2-[(4-pyridinylMethyl)aMino]-
  • Motesanib Base
  • AMG-706(Motesanib)
  • Motesanib (AMG-706) Base)
  • motesanib
  • N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide
  • N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide
  • N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide,AMG706
  • D06678
  • 2,4-Imidazolidinedione,5-(3-bromophenyl)-6-methyl-
  • 453562-69-1
  • API
  • Inhibitors
  • Antineoplastic