ChemicalBook > CAS DataBase List > Motesanib
Motesanib
- Product Name
- Motesanib
- CAS No.
- 453562-69-1
- Chemical Name
- Motesanib
- Synonyms
- D06678;CS-1108;motesanib;Motesanib Base;AMG 706; AMG-706;AMG-706(Motesanib);Motesanib (AMG-706) Base);2,4-Imidazolidinedione,5-(3-bromophenyl)-6-methyl-;N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide;N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide,AMG706
- CBNumber
- CB01518524
- Molecular Formula
- C22H23N5O
- Formula Weight
- 373.45
- MOL File
- 453562-69-1.mol
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Motesanib Property
- Melting point:
- 147-150°C
- Boiling point:
- 517.3±50.0 °C(Predicted)
- Density
- 1.251
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- White powder solid.
- pka
- 11.75±0.40(Predicted)
- color
- Pale Yellow
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Safety
- HS Code
- 2933399990
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
TRC
- Product number
- M732500
- Product name
- Motesanib
- Packaging
- 50mg
- Price
- $165
- Updated
- 2021/12/16
Usbiological
- Product number
- 017881
- Product name
- Motesanib
- Packaging
- 5mg
- Price
- $496
- Updated
- 2021/12/16
Adipogen Life Sciences
- Product number
- SYN-1055-M100
- Product name
- Motesanib
- Purity
- ≥95%
- Packaging
- 100mg
- Price
- $1069
- Updated
- 2021/12/16
AK Scientific
- Product number
- X4931
- Product name
- Motesanib
- Packaging
- 500mg
- Price
- $1265
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 132644
- Product name
- N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide
- Purity
- 97%
- Packaging
- 250mg
- Price
- $630
- Updated
- 2021/12/16
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Motesanib Chemical Properties,Usage,Production
Chemical Properties
Pale Yellow Solid
Uses
Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3, PDGFR, c-Kit and Ret with IC50 of 2 nM/3 nM/6 nM, 84 nM, 8 nM and 59 nM, respectively.
Uses
Motesanib is an oral angiogenesis inhibitor, demonstrates clinical efficacy in advanced thymoma.
Definition
ChEBI: Motesanib is a pyridinecarboxamide.
target
VEGFR1
Motesanib Preparation Products And Raw materials
Raw materials
Preparation Products
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Motesanib Suppliers
- Tel
- 15076683720
- Fax
- 022-23754520
- klq@cw-bio.com
- Country
- China
- ProdList
- 4966
- Advantage
- 55
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-20221225 13917446399
- Fax
- QQ:115820162
- sales@zhiwe.net
- Country
- China
- ProdList
- 627
- Advantage
- 61
- Tel
- +86-21-20908456
- Fax
- 021-58180499
- sales@BioChemBest.com
- Country
- China
- ProdList
- 6005
- Advantage
- 61
- Tel
- 1-(800)-881-8210
- Fax
- 615-250-9817
- inquiries@lgmpharma.com
- Country
- United States
- ProdList
- 2123
- Advantage
- 70
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- +86 (531) 88811783
- Fax
- +86 (531) 55696010 QQ 1762738062
- sales@trio-pharmatech.com (International market)
- Country
- China
- ProdList
- 1856
- Advantage
- 62
- Tel
- 029-86538357
- Fax
- 029-87871708
- Country
- China
- ProdList
- 234
- Advantage
- 57
- Tel
- 0411-62910999 13889544652
- sales@meilune.com
- Country
- China
- ProdList
- 4727
- Advantage
- 58
- Tel
- 010-56645598 13366904824
- Fax
- 01062230033
- bjkaida@163.com
- Country
- China
- ProdList
- 1637
- Advantage
- 59
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View Lastest Price from Motesanib manufacturers
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- motesanib 453562-69-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-26
Career Henan Chemical Co
- Product
- Motesanib 453562-69-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 100kgs
- Release date
- 2020-01-02
453562-69-1, MotesanibRelated Search:
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Dimethyl phthalate
Dimethyl ether
ETHANE
2-[(6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone
N-[4-[5-(1,3-BENZODIOXOL-5-YL)-3-METHOXY-1H-1,2,4-TRIAZOL-1-YL]PHENYL]-2-(PHENYLTHIO)ACETAMIDE
Compound 23
ERK Inhibitor
6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID
Motesanib