H-1152Glycyl, Dihydrochloride

Product Name: H-1152Glycyl, Dihydrochloride
CAS No.: 913844-45-8
Chemical Name: H-1152Glycyl, Dihydrochloride
Synonyms: Glycyl-H 1152 2HCl;Rho Kinase Inhibitor IV;Glycyl H-1152 hydrochloride;H-1152Glycyl, Dihydrochloride;(S)-Glycyl-H-1152 (hydrochloride);Glycyl H1152 hydrochloride,Glycyl H 1152 hydrochloride;(S)-(+)-4-Glycyl-2-methyl-1-[(4-methyl-5-isoquinolinyl) sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride;(2S)-4-(Aminoacetyl)hexahydro -2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepine Dihydrochloride;2-Amino-1-[(3S)-hexahydro-3-methyl-4-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepin-1-yl]ethanone Hydrochloride
CBNumber: CB21564868
Molecular Formula: C18H26Cl2N4O3S
Formula Weight: 0
MOL File: 913844-45-8.mol

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H-1152Glycyl, Dihydrochloride Property

Melting point:: 190-192°C
storage temp.: Refrigerator
solubility: Methanol (Slightly), Water (Slightly)
form: Solid
color: Pale Yellow to Beige
Stability:: Hygroscopic
CAS DataBase Reference: 913844-45-8

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P307+P311IF exposed: call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 13332
Product name: (S)-Glycyl-H-1152 (hydrochloride)
Purity: ≥98%
Packaging: 500μg
Price: $93
Updated: 2024/03/01

Cayman Chemical

Product number: 13332
Product name: (S)-Glycyl-H-1152 (hydrochloride)
Purity: ≥98%
Packaging: 1mg
Price: $176
Updated: 2024/03/01

Cayman Chemical

Product number: 13332
Product name: (S)-Glycyl-H-1152 (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $728
Updated: 2024/03/01

Cayman Chemical

Product number: 13332
Product name: (S)-Glycyl-H-1152 (hydrochloride)
Purity: ≥98%
Packaging: 10mg
Price: $1274
Updated: 2024/03/01

Usbiological

Product number: 013030
Product name: H-1152 Glycyl Dihydrochloride
Packaging: 1mg
Price: $460
Updated: 2021/12/16

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H-1152Glycyl, Dihydrochloride Chemical Properties,Usage,Production

Chemical Properties

Pale-Yellow Solid

Uses

A glycyl analog of Rho-kinase (ROCK) inhibitor that inhibits ROCK with an improved selectitity; for treatment of hypertension and arteriosclerosis.

Biological Activity

Glycyl analog of the Rho-kinase inhibitor H 1152 dihydrochloride ((S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride ) that displays improved ROCKII selectivity. IC 50 values are 0.0118, 2.35, 2.57, 3.26, > 10 and >10 μ M for ROCKII, Aurora A, CAMKII, PKG, PKA and PKC respectively.

storage

room temperature (desiccate)

H-1152Glycyl, Dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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H-1152Glycyl, Dihydrochloride Suppliers

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913844-45-8, H-1152Glycyl, DihydrochlorideRelated Search:

H-1152Glycyl, Dihydrochloride FASUDIL (S)-(+)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLYNYL)SULFONYL]HOMOPIPERAZINE

(2S)-4-(Aminoacetyl)hexahydro -2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepine Dihydrochloride

2-Amino-1-[(3S)-hexahydro-3-methyl-4-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepin-1-yl]ethanone Hydrochloride

(S)-(+)-4-Glycyl-2-methyl-1-[(4-methyl-5-isoquinolinyl) sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride

(S)-Glycyl-H-1152 (hydrochloride)

Glycyl-H 1152 2HCl

Rho Kinase Inhibitor IV

H-1152Glycyl, Dihydrochloride

Glycyl H-1152 hydrochloride

Glycyl H1152 hydrochloride,Glycyl H 1152 hydrochloride

913844-45-8

C18H26Cl2N4O3S

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