ChemicalBook > CAS DataBase List > 1,4-Cyclohexanedione mono(2,2-dimethyltrimethylene ketal)

1,4-Cyclohexanedione mono(2,2-dimethyltrimethylene ketal)

Product Name
1,4-Cyclohexanedione mono(2,2-dimethyltrimethylene ketal)
CAS No.
69225-59-8
Chemical Name
1,4-Cyclohexanedione mono(2,2-dimethyltrimethylene ketal)
Synonyms
3,3-DIMETHYL-1,5-DIOXASPIRO[5.5]UNDECAN-9-ONE;1,4-CYCLOHEXANEDIONE MONO-2,2-DIMETHYLTRIMETHYLENE KETAL;ene ketaL;ohexanedione mono-2,2-dimethyL;1,4-CYCLOHEXANEDIONE MONONEOPENTYL KETAL;,3-Dimethyl-1,5-dioxaspiro[5.5]undecan-9-one;3,3-Dimethyl-1,5-dioxaspiro[5.5]undecan-8-one;1,5-Dioxaspiro[5.5]undecan-9-one,3,3-diMethyl-;1,4-cyclohexanedione mono-2,2-dimethyl-trimethyle;1,4-Cyclohexanedione mono(2,2-dimethyltrimethylene
CBNumber
CB2161811
Molecular Formula
C11H18O3
Formula Weight
198.26
MOL File
69225-59-8.mol
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1,4-Cyclohexanedione mono(2,2-dimethyltrimethylene ketal) Property

Melting point:
45-50 °C(lit.)
Boiling point:
70 °C(Press: 0.05 Torr)
Density 
1.08±0.1 g/cm3(Predicted)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Acetone, Dichloromethane, Ethyl Acetate, Methanol,
form 
Solid
color 
White
BRN 
3541930
InChI
InChI=1S/C11H18O3/c1-10(2)7-13-11(14-8-10)5-3-9(12)4-6-11/h3-8H2,1-2H3
InChIKey
COKVDTKAWIFNTH-UHFFFAOYSA-N
SMILES
O1C2(CCC(=O)CC2)OCC(C)(C)C1
CAS DataBase Reference
69225-59-8(CAS DataBase Reference)
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Safety

Risk Statements 
36/37/38-52/53
Safety Statements 
24/25-61
WGK Germany 
3
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
215570
Product name
1,4-Cyclohexanedione mono(2,2-dimethyltrimethylene ketal)
Purity
95%
Packaging
10g
Price
$173
Updated
2023/01/07
TCI Chemical
Product number
C2328
Product name
1,4-Cyclohexanedione Mono-2,2-dimethyltrimethylene Ketal
Purity
>98.0%(GC)
Packaging
5g
Price
$59
Updated
2025/07/31
TCI Chemical
Product number
C2328
Product name
1,4-Cyclohexanedione Mono-2,2-dimethyltrimethylene Ketal
Purity
>98.0%(GC)
Packaging
25g
Price
$178
Updated
2025/07/31
TRC
Product number
C987895
Product name
1,4-Cyclohexanedione mono(2,2-dimethyltrimethylene ketal)
Packaging
10g
Price
$165
Updated
2021/12/16
AK Scientific
Product number
P711
Product name
3,3-Dimethyl-1,5-dioxaspiro[5.5]undecan-9-one
Packaging
5g
Price
$20
Updated
2021/12/16
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1,4-Cyclohexanedione mono(2,2-dimethyltrimethylene ketal) Chemical Properties,Usage,Production

Chemical Properties

White to yellowish powder

Uses

1,4-Cyclohexanedione mono(2,2-dimethyltrimethylene ketal)is a reagent used in the preparation of carbazole derivatives.

Synthesis Reference(s)

Synthetic Communications, 14, p. 39, 1984 DOI: 10.1080/00397918408060862

Synthesis

69825-15-6

69225-59-8

The general procedure for the synthesis of 3,3-dimethyl-1,5-dioxaspiro[5.5]undecan-9-one using the compound (CAS: 69825-15-6) as starting material was as follows: first, 6.1 mg (0.02 mmol) of sodium 2-iodobenzenesulfonate, 0.49 g (0.8 mmol) of Oxone? (registered trademark) powder, 0.5 g (3.5 mmol) anhydrous sodium sulfate and 200 mg (1 mmol) 3,3-dimethyl-1,5-dioxaspiro[5.5]undecan-9-ol were added to 5 mL of ethyl acetate. Subsequently, the reaction mixture was heated and stirred at 70°C for 8 hours under nitrogen protection. Upon completion of the reaction, post-processing was carried out according to the method of Example 1, resulting in the target product 3,3-dimethyl-1,5-dioxaspiro[5.5]undecan-9-one. The yield of the compound was determined to be 91%, as shown in Table 2.

References

[1] Patent: EP2085373, 2009, A1. Location in patent: Page/Page column 12; 14-15
[2] Journal of Medicinal Chemistry, 1981, vol. 24, # 3, p. 341 - 346

1,4-Cyclohexanedione mono(2,2-dimethyltrimethylene ketal) Preparation Products And Raw materials

Raw materials

Preparation Products

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1,4-Cyclohexanedione mono(2,2-dimethyltrimethylene ketal) Suppliers

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View Lastest Price from 1,4-Cyclohexanedione mono(2,2-dimethyltrimethylene ketal) manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
1,4-Cyclohexanedione mono(2,2-dimethyltrimethylene ketal) 69225-59-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-12-02
Speranza Chemical Co., Ltd.
Product
1,4-Cyclohexanedione Mono-2,2-dimethyl trimethylene Ketal 69225-59-8
Price
US $20.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200tons/ year
Release date
2020-03-11
Shanghai Bojing Chemical Co.,Ltd.
Product
3,3-Dimethyl-15-dioxaspiro[5.5]undecan-9-one 69225-59-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99.5%
Supply Ability
10MT
Release date
2024-03-13

69225-59-8, 1,4-Cyclohexanedione mono(2,2-dimethyltrimethylene ketal)Related Search:

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