ChemicalBook > CAS DataBase List > 1,4-Cyclohexanedione

1,4-Cyclohexanedione

Product Name
1,4-Cyclohexanedione
CAS No.
637-88-7
Chemical Name
1,4-Cyclohexanedione
Synonyms
CHD;Cyclohexane-1,4-dione;CYCLOHEXANEDIONE;1,4-Cyclohexadione;Tetrahydroquinone;1,4-CYCHEXANEDIONE;1,4-CYCLOHEXANDIONE;1,4-cyclohexanedion;Cyclohexan-1,4-dione;1,4-Dioxocyclohexane
CBNumber
CB7138205
Molecular Formula
C6H8O2
Formula Weight
112.13
MOL File
637-88-7.mol
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1,4-Cyclohexanedione Property

Melting point:
77-78.5 °C (lit.)
Boiling point:
112 °C (19.5026 mmHg)
Density 
1.0861
refractive index 
1.4570 (estimate)
Flash point:
132 °C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in methanol and ethanol.
form 
Crystalline Powder or Flakes
color 
Light yellow to yellow or beige
BRN 
774152
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
LogP
-0.910 (est)
CAS DataBase Reference
637-88-7(CAS DataBase Reference)
NIST Chemistry Reference
1,4-Cyclohexanedione(637-88-7)
EPA Substance Registry System
1,4-Cyclohexanedione (637-88-7)
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Safety

Hazard Codes 
Xi
Safety Statements 
22-24/25
WGK Germany 
3
8
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29142900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
125423
Product name
1,4-Cyclohexanedione
Purity
98%
Packaging
10g
Price
$60.5
Updated
2024/03/01
Sigma-Aldrich
Product number
125423
Product name
1,4-Cyclohexanedione
Purity
98%
Packaging
50g
Price
$111
Updated
2024/03/01
TCI Chemical
Product number
C0730
Product name
1,4-Cyclohexanedione
Purity
>98.0%(GC)
Packaging
25g
Price
$54
Updated
2024/03/01
TCI Chemical
Product number
C0730
Product name
1,4-Cyclohexanedione
Purity
>98.0%(GC)
Packaging
500g
Price
$527
Updated
2024/03/01
Alfa Aesar
Product number
A11100
Product name
1,4-Cyclohexanedione, 98%
Packaging
25g
Price
$58
Updated
2024/03/01
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1,4-Cyclohexanedione Chemical Properties,Usage,Production

Chemical Properties

tan or yellow crystalline powder

Uses

1,4-Cyclohexanedione is used in the preparation of 1,4 benzoquinone and bromoorganics. It is also used to study the influence of visible light on the bromate-1,4-cyclohexanedione-ferroin oscillating reaction. It plays a vital role in pharmaceuticals, plant growth regulator and as a conducting material.

Definition

ChEBI: 1,4-Cyclohexanedione is a cyclohexanedione with oxo substituents at positions 1 and 4.

Preparation

Synthesis of 1,4-cyclohexanedione: put diethyl succinylsuccinate into a flask, add a mixture of concentrated sulfuric acid, water and ethanol, reflux in oil solution for 5 days, cool, and neutralize to pH with ammonia water = 8; then extract 4 times with chloroform, and recover the chloroform to obtain the crude product; then the crude product is subjected to vacuum distillation, and the distillate is poured into cold petroleum ether, filtered, and air-dried to obtain 1,4-cyclohexanedi Ketone Products.

Synthesis Reference(s)

Synthesis, p. 165, 1981 DOI: 10.1055/s-1981-29377

General Description

1,4-Cyclohexanedione(CHD) undergoes uncatalyzed oscillatory reactions during oxidation by acidic bromate in nitric acid and sulphuric acid solution. It reacts with acidic bromate to form 1,4-dihydroxybenzene which on further oxidation and bromination yields 1,4-benzoquinone and bromoorganics.

Pharmacology

The cyclohexanedione (CHD) herbicides inhibit fatty acid synthesis in plants by interfering with the activity of the enzyme Acetyl-Coenzyme A Carboxylase (ACCase). ACCase-inhibiting herbicides provide excellent control of grass weeds in dicotyledonous and some grass crops. A less-sensitive ACCase mediates the intrinsic resistance of dicotyledonous plants to the AOPP and CHD herbicides (34,35). Although grasses are target species of this group of herbicides, not all are equally affected, and sensitivity differences can occur between varieties or even within a genus.

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1,4-Cyclohexanedione Suppliers

Yangzhou shilihecheng Technology Co., Ltd
Tel
15312801805
Email
545495101@qq.com
Country
CHINA
ProdList
43
Advantage
58
Hebei Maison Chemical Co.,Ltd.
Tel
0311-85381176 15511852758
Fax
0311-83832777
Email
ruby@maisonchem.com.cn
Country
China
ProdList
545
Advantage
58
Hebei Wenjing United Technology Co. LTD
Tel
18633031353 17734561860
Email
16021353@qq.com
Country
China
ProdList
55
Advantage
58
Wuhan EnTai Technology Development Co,.Ltd
Tel
86-27-82330560
Fax
86-27-82330547
Email
2536851935@qq.com
Country
China
ProdList
347
Advantage
69
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
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View Lastest Price from 1,4-Cyclohexanedione manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
1,4-Cyclohexanedione 637-88-7
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 MT
Release date
2024-11-08
Hebei Yanxi Chemical Co., Ltd.
Product
1,4-Cyclohexanedione 637-88-7
Price
US $40.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-10-16
Hebei Weibang Biotechnology Co., Ltd
Product
1,4-Cyclohexanedione 637-88-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2022-11-14

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