trans-4-Aminocyclohexanol
Description Reference- Product Name
- trans-4-Aminocyclohexanol
- CAS No.
- 27489-62-9
- Chemical Name
- trans-4-Aminocyclohexanol
- Synonyms
- (1r,4r)-4-aminocyclohexanol;(1s,4s)-4-Aminocyclohexanol;trans-4-aminocyclohexan-1-ol;AURORA KA-7506;trans-4-AminocycL;TIMTEC-BB SBB005825;trans-4-Aminocyclohe;Ambroxol Impurity 36;4-(E)-aMino cyclohexano;Ammonia bromine AMB - F
- CBNumber
- CB7139383
- Molecular Formula
- C6H13NO
- Formula Weight
- 115.17
- MOL File
- 27489-62-9.mol
trans-4-Aminocyclohexanol Property
- Melting point:
- 108-113°C
- Boiling point:
- 127 °C / 14mmHg
- Density
- 0.9837 (rough estimate)
- refractive index
- 1.4713 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Crystals
- pka
- 15.12±0.40(Predicted)
- color
- White to almost white
- Water Solubility
- Soluble in water.
- Sensitive
- Hygroscopic
- InChI
- InChI=1S/C6H13NO/c7-5-1-3-6(8)4-2-5/h5-6,8H,1-4,7H2/t5-,6-
- InChIKey
- IMLXLGZJLAOKJN-IZLXSQMJSA-N
- SMILES
- [C@@H]1(O)CC[C@@H](N)CC1
- LogP
- -0.4
- CAS DataBase Reference
- 27489-62-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,C,Xn
- Risk Statements
- 36/37/38-34-41-37/38-22
- Safety Statements
- 26-37/39-45-36/37/39-39
- RIDADR
- 3259
- Hazard Note
- Irritant
- HazardClass
- 8
- PackingGroup
- Ⅲ
- HS Code
- 29221990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A1160
- Product name
- trans-4-Aminocyclohexanol
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $33
- Updated
- 2025/07/31
- Product number
- A1160
- Product name
- trans-4-Aminocyclohexanol
- Purity
- >98.0%(GC)
- Packaging
- 500g
- Price
- $363
- Updated
- 2025/07/31
- Product number
- A603995
- Product name
- trans-4-Aminocyclohexanol
- Packaging
- 5g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- A603995
- Product name
- trans-4-Aminocyclohexanol
- Packaging
- 100g
- Price
- $275
- Updated
- 2021/12/16
- Product number
- A603995
- Product name
- trans-4-Aminocyclohexanol
- Packaging
- 500g
- Price
- $615
- Updated
- 2021/12/16
trans-4-Aminocyclohexanol Chemical Properties,Usage,Production
Description
Trans-4-Aminocyclohexanol is also named as Cis-4-Aminocyclohexanol. It was a medical intermediate of ambroxol, which is used in the treatment of respiratory diseases associated with viscid or excessive mucus.1 It is used as a raw material in organic synthesis, such as in the synthesis of N-substituted 7-azabicyclo [2.2.1] hepatanes, which are good substrates for microbial oxidation of unactivated carbons by B.bassiana.2
Reference
- Y. Jian, Improved Process of the Synthesis of Trans-4-aminocyclohexanol, Fine Chemicals, 2000, vol. 2
- H. F. Olivo, M. S. Hemenway, M. H. Gezginci, Synthesis and Microbial Hydroxylation of Some Azabicycloalkanes, Tetrahedron Letters, 1998, vol. 39, pp. 1309-1312
Chemical Properties
white to light yellow crystal powder
Uses
trans-4-aminocyclohexanol be used as organic intermediates.
Uses
trans-4-Aminocyclohexanol is used as raw material in organic synthesis and is an important intermediate in the synthesis of drugs such as Ambroxol hydrochloride. It can react with butyric acid-(2-chloro-ethyl ester) to get butyric acid 4-amino-cyclohexyl ester. This reaction needs catalytic agent Aspergillus niger lipase and solvent 2-methyl-butan-2-ol.
trans-4-Aminocyclohexanol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from trans-4-Aminocyclohexanol manufacturers
- Product
- trans-4-Aminocyclohexanol 27489-62-9
- Price
- US $10.00/KG
- Min. Order
- 100KG
- Purity
- 99%
- Supply Ability
- 100 mt
- Release date
- 2024-11-21
- Product
- Trans-4-Aminocyclohexanol 27489-62-9
- Price
- US $180.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-05-23
- Product
- trans-4-Aminocyclohexanol 27489-62-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-13