trans-4-Aminocyclohexanol

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trans-4-Aminocyclohexanol

Description Reference

Product Name: trans-4-Aminocyclohexanol
CAS No.: 27489-62-9
Chemical Name: trans-4-Aminocyclohexanol
Synonyms: (1r,4r)-4-aminocyclohexanol;(1s,4s)-4-Aminocyclohexanol;trans-4-aminocyclohexan-1-ol;AURORA KA-7506;trans-4-AminocycL;TIMTEC-BB SBB005825;trans-4-Aminocyclohe;Ambroxol Impurity 36;4-(E)-aMino cyclohexano;Ammonia bromine AMB - F
CBNumber: CB7139383
Molecular Formula: C6H13NO
Formula Weight: 115.17
MOL File: 27489-62-9.mol

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trans-4-Aminocyclohexanol Property

Melting point:: 108-113°C
Boiling point:: 127 °C / 14mmHg
Density: 0.9837 (rough estimate)
refractive index: 1.4713 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Crystals
pka: 15.12±0.40(Predicted)
color: White to almost white
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
LogP: -0.4
CAS DataBase Reference: 27489-62-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,C,Xn
Risk Statements: 36/37/38-34-41-37/38-22
Safety Statements: 26-37/39-45-36/37/39-39
RIDADR: 3259
Hazard Note: Irritant
HazardClass: 8
PackingGroup: Ⅲ
HS Code: 29221990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: A1160
Product name: trans-4-Aminocyclohexanol
Purity: >98.0%(GC)
Packaging: 25g
Price: $33
Updated: 2024/03/01

TCI Chemical

Product number: A1160
Product name: trans-4-Aminocyclohexanol
Purity: >98.0%(GC)
Packaging: 500g
Price: $363
Updated: 2024/03/01

Alfa Aesar

Product number: B22365
Product name: trans-4-Aminocyclohexanol
Purity: 98+%
Packaging: 5g
Price: $42.65
Updated: 2024/03/01

Alfa Aesar

Product number: B22365
Product name: trans-4-Aminocyclohexanol
Purity: 98+%
Packaging: 25g
Price: $138.65
Updated: 2024/03/01

Alfa Aesar

Product number: B22365
Product name: trans-4-Aminocyclohexanol
Purity: 98+%
Packaging: 100g
Price: $408.65
Updated: 2024/03/01

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trans-4-Aminocyclohexanol Chemical Properties,Usage,Production

Description

Trans-4-Aminocyclohexanol is also named as Cis-4-Aminocyclohexanol. It was a medical intermediate of ambroxol, which is used in the treatment of respiratory diseases associated with viscid or excessive mucus.¹ It is used as a raw material in organic synthesis, such as in the synthesis of N-substituted 7-azabicyclo [2.2.1] hepatanes, which are good substrates for microbial oxidation of unactivated carbons by B.bassiana.²

Reference

Y. Jian, Improved Process of the Synthesis of Trans-4-aminocyclohexanol, Fine Chemicals, 2000, vol. 2
H. F. Olivo, M. S. Hemenway, M. H. Gezginci, Synthesis and Microbial Hydroxylation of Some Azabicycloalkanes, Tetrahedron Letters, 1998, vol. 39, pp. 1309-1312

Chemical Properties

white to light yellow crystal powder

Uses

trans-4-aminocyclohexanol be used as organic intermediates.

Uses

trans-4-Aminocyclohexanol is used as raw material in organic synthesis and is an important intermediate in the synthesis of drugs such as Ambroxol hydrochloride. It can react with butyric acid-(2-chloro-ethyl ester) to get butyric acid 4-amino-cyclohexyl ester. This reaction needs catalytic agent Aspergillus niger lipase and solvent 2-methyl-butan-2-ol.

trans-4-Aminocyclohexanol Preparation Products And Raw materials

Raw materials

1,4-Cyclohexanedione Lithium Aluminum Hydride

Preparation Products

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View Lastest Price from trans-4-Aminocyclohexanol manufacturers

airuikechemical co., ltd.

Product: Trans-4-aminocyclohexanol 27489-62-9
Price: US $0.00-0.00/Kg
Min. Order: 1Kg
Purity: 99.9%
Supply Ability: 200tons
Release date: 2024-04-08

Hebei Yanxi Chemical Co., Ltd.

Product: trans-4-Aminocyclohexanol 27489-62-9
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-10-08

Hebei Guanlang Biotechnology Co., Ltd.

Product: trans-4-Aminocyclohexanol 27489-62-9
Price: US $10.00/KG
Min. Order: 100KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2021-08-09

27489-62-9, trans-4-AminocyclohexanolRelated Search:

Molasses 1-Methylcyclohexanol Cyclohexanol trans-4-Aminocyclohexanol hydrochloride 2-Aminocyclohexanol trans,trans-2,4-Undecadienal Cyclamic acid 4-Aminocyclohexanol Cyclohexanol, 4-amino-1-methyl-, trans- (9CI) (E,E)-2,4-Hexadien-1-ol TRANS-4-AMINO-CYCLOHEXANE CARBOXYLIC ACID HYDROCHLORIDE trans-4-Aminocyclohexanecarbonitrile Methyl trans-4-AMinocyclohexanecarboxylate Hydrochloride Trans-4-Propylcyclohexyl-Benzene Trans-1-(bromomethyl)-4-propylcyclohexane 4-(trans-4-Propylcyclohexyl)phenol trans-4-(4n-Heptylcyclohexyl)phenol trans-4-ethylcyclohexylbenzene

trans-4-Aminocyclohexanol,97%

trans-4-Aminocyclohexanol

(1r,4r)-4-aminocyclohexanol

(1s,4s)-4-Aminocyclohexanol

Trans-4-Amimocyclohexanol

Cyclohexanol, 4-amino-, trans-

(1α)-4β-Aminocyclohexanol

trans-4-Aminocyclohexanol ,99%

trans-4-Aminocyclohe

Trans-4-aMniocyclohexanol

4-trans-Hydroxycyclohexylamine

4-(E)-aMino cyclohexano

Trans-4-aMino cyclohexanol (TACH)

<i>trans</i>-4-Aminocyclohexanol

The trans-aminocyclohexanol

trans-1-amino-4-cyclohexanol

TIMTEC-BB SBB005825

TRANS-4-AMINO-1-HYDROXYCYCLOHEXANE

AMINOCYCLOHEXANOL(TRANS-4)

trans-4-aminocyclohexan-1-ol

4-Trans amino cyclohexanol

trans-4-Aminocyclohexanol, 98+%

AURORA KA-7506

trans-4-hydroxycyclohexylamine

trans-4-Aminocyclohexanol 97%

Trans-4-Aminocyclohexanol ( For Ambroxol Hcl )

trans-4-AminocycL

Ambroxol Hydrochloride Impurity 4

trans-4-Aminocyclohexanol&gt

Ambroxol Impurity 36

Ammonia bromine AMB - F

Trans-4-Amonocyclohexanol

Trans-4-amino cyclohexyl phenol

Anti-4-amino cyclohexanol

rans-4-Aminocyclohexanol

(1r,4r)-4-aminocyclohexan-1-ol

(1r,4r)-4-aminocyclohexanol/trans-4-Aminocyclohexanol

27489-62-9

50910-58-5

27489-63-9

chiral

Amines

blocks

BuildingBlocks

Ambroxol