AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT

Product Name: AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT
CAS No.: 54472-66-1
Chemical Name: AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT
Synonyms: GHIH;Somatostatin monoacetate;SOMATOSTATIN 14, ACETATE;Cyclic somatostatin Acetate;Somatostatin (sheep), monoacetate (salt);AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT;Somatostatin-14 (human, mouse, rat, porcine, bovine, ovine) (acetate);H-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH (DISULFIDE BRIDGE: 3-14), ACETATE SALT
CBNumber: CB2166795
Molecular Formula: C78H108N18O21S2
Formula Weight: 1697.95
MOL File: Mol file

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AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT Property

storage temp.: Store at -20°C
solubility: Water: 0.3 mg/ml
form: A powder

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 20809
Product name: Somatostatin-14 (acetate)
Purity: ≥98%
Packaging: 1mg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 20809
Product name: Somatostatin-14 (acetate)
Purity: ≥98%
Packaging: 5mg
Price: $341
Updated: 2024/03/01

Cayman Chemical

Product number: 20809
Product name: Somatostatin-14 (acetate)
Purity: ≥98%
Packaging: 10mg
Price: $645
Updated: 2024/03/01

Cayman Chemical

Product number: 20809
Product name: Somatostatin-14 (acetate)
Purity: ≥98%
Packaging: 25mg
Price: $1163
Updated: 2024/03/01

AK Scientific

Product number: 5026EA
Product name: Somatostatinmonoacetate
Packaging: 1mg
Price: $179
Updated: 2021/12/16

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AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT Chemical Properties,Usage,Production

Description

Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin. It is a somatostatin (SST) receptor agonist that binds to SST₁, SST₂, SST₃, SST₄, and SST₅ (IC₅₀s = 0.22, 0.10, 0.28, 1.23, and 0.30 nM, respectively, in CCL39 cells expressing human recombinant receptors). It inhibits cAMP accumulation induced by forskolin in CCL39 cells expressing human recombinant SST₁, SST₂, SST₃, SST₄, and SST₅ (EC₅₀s = 6.16, 4.37, 17.38, 2.95, and 4.67 nM, respectively). Somatostatin-14 inhibits the release of growth hormone, prolactin, thyrotropin, glucagon, and insulin, as well as other signaling molecules.

References

[1] D J HADJIDAKIS. Differences between somatostatin-28 and somatostatin-14 with respect to their biological effects in healthy humans and acromegalics.[J]. Clinical physiology and biochemistry, 1986, 4 6: 372-383.
[2] S SIEHLER D H K Seuwen. Characterisation of human recombinant somatostatin receptors. 1. Radioligand binding studies.[J]. Naunyn-Schmiedeberg’s archives of pharmacology, 1999, 360 5: 488-499. DOI: 10.1007/s002109900141
[3] S SIEHLER D H. Characterisation of human recombinant somatostatin receptors. 3. Modulation of adenylate cyclase activity.[J]. Naunyn-Schmiedeberg’s archives of pharmacology, 1999, 360 5: 510-521. DOI: 10.1007/s002109900143
[4] GILLIES G. Somatostatin: the neuroendocrine story.[J]. Trends in pharmacological sciences, 1997, 18 3: 87-95. DOI: 10.1016/s0165-6147(96)01032-2
[5] IAN M P JOSEPH. A model for integrative study of human gastric acid secretion.[J]. Journal of applied physiology, 2003, 94 4: 1602-1618. DOI: 10.1152/japplphysiol.00281.2002

AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT Suppliers

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54472-66-1, AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALTRelated Search:

D-BETA-NAL-CYWKVCT-NH2 (DISULFIDE BRIDGE: 2-7) SOMATOSTATIN-25 Molidustat(BAY 85-3934) (LEU8,D-TRP22,TYR25)-SOMATOSTATIN 28 prosomatostatin SOMATOSTATIN 28, CYCLIC SOMATOSTATIN-28 (1-12) SOMATOSTATIN-28 (1-14)

H-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH (DISULFIDE BRIDGE: 3-14), ACETATE SALT

AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT

SOMATOSTATIN 14, ACETATE

Somatostatin monoacetate

GHIH

Somatostatin (sheep), monoacetate (salt)

Somatostatin-14 (human, mouse, rat, porcine, bovine, ovine) (acetate)

Cyclic somatostatin Acetate

54472-66-1

peptide