Description References
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2,5-Dimethylphenol

Description References
Product Name
2,5-Dimethylphenol
CAS No.
95-87-4
Chemical Name
2,5-Dimethylphenol
Synonyms
2,5-XYLENOL;2,5-DMP;1,2,5-Xylenol;P-XYLENOL;FEMA 3595;3,6-Xylenol;PARA-XYLENOL;XYLENOL(2,5-);2.5-DiMethylph;2,5-DiMethylphen
CBNumber
CB2167439
Molecular Formula
C8H10O
Formula Weight
122.16
MOL File
95-87-4.mol
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2,5-Dimethylphenol Property

Melting point:
75-77 °C
Boiling point:
212 °C(lit.)
Density 
0.971 g/mL at 25 °C(lit.)
vapor pressure 
0.208 hPa (25 °C)
FEMA 
3595 | 2,5-XYLENOL
refractive index 
1.5120
Flash point:
85 °C
storage temp. 
Store below +30°C.
solubility 
3.54g/l slightly soluble
form 
Crystals
pka
pK1:10.22 (25°C)
color 
slightly brown
Odor
at 0.10 % in propylene glycol. sweet naphthyl phenolic smoke bacon
Odor Type
phenolic
explosive limit
1.4%(V)
Water Solubility 
1 g/100 mL (60 ºC)
Merck 
14,10082
JECFA Number
706
BRN 
1099260
Exposure limits
ACGIH: TWA 1 ppm
InChIKey
NKTOLZVEWDHZMU-UHFFFAOYSA-N
LogP
2.34-2.6 at 25℃
CAS DataBase Reference
95-87-4(CAS DataBase Reference)
NIST Chemistry Reference
Phenol, 2,5-dimethyl-(95-87-4)
EPA Substance Registry System
2,5-Dimethylphenol (95-87-4)
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Safety

Hazard Codes 
T,N
Risk Statements 
24/25-34-51/53
Safety Statements 
26-36/37/39-45-61
RIDADR 
UN 2261 6.1/PG 2
WGK Germany 
3
RTECS 
ZE5775000
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
II
HS Code 
29071400
Hazardous Substances Data
95-87-4(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W359505
Product name
2,5-Xylenol
Purity
≥99%, FG
Packaging
1kg
Price
$229
Updated
2024/03/01
Sigma-Aldrich
Product number
W359505
Product name
2,5-Xylenol
Purity
≥99%, FG
Packaging
5kg
Price
$703
Updated
2024/03/01
Sigma-Aldrich
Product number
D174602
Product name
2,5-Dimethylphenol
Purity
≥99%
Packaging
5g
Price
$53.7
Updated
2024/03/01
Sigma-Aldrich
Product number
8.03771
Product name
2,5-Dimethylphenol
Purity
for synthesis
Packaging
5G
Price
$41.8
Updated
2024/03/01
Sigma-Aldrich
Product number
8.03771
Product name
2,5-Dimethylphenol
Purity
for synthesis
Packaging
250G
Price
$93.4
Updated
2024/03/01
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2,5-Dimethylphenol Chemical Properties,Usage,Production

Description

2, 5-dimethylphenol (also known as 2, 5-xylenol, or p-xylenol, chemical formula: (CH3)2C6H3OH.) is a chemical compound as one of the six isomers of xylenol. It is found in alcoholic beverages, coffee and whisky. It is a kind of flavoring agent belonging to the family of Ortho Cresols. One of its applications is for the synthesis of Mexilethine. It has important industrial importance, e.g. for the manufacture of antioxidants. It is also a monomer for the poly (p-phenylene oxide) engineering resins through carbon-oxygen oxidative coupling. It is traditionally extracted from the coal tar.

References

https://en.wikipedia.org/wiki/2,6-Xylenol
https://en.wikipedia.org/wiki/Xylenol
https://pubchem.ncbi.nlm.nih.gov/compound/2_5-dimethylphenol#section=Top

Chemical Properties

WHITE TO CREAM COLORED CRYSTALS

Chemical Properties

2,5-Xylenol has a creosote, sweet, medicinal taste.

Occurrence

Reported found in coffee, smoked fatty fish, processed lean fish, malt whiskey, Scotch blended whiskey, katsuobushi (dried bonito) and kumazasa (Sasa albo-marginata).

Uses

Used to make phenolic resins and (in isomeric mixtures) as an antioxidant for lubricating oils, gasoline, and elastomers. Also used as perfuming agents.

Definition

ChEBI: 2,5-xylenol is a member of the class of phenols that phenol substituted by methyl groups at positions 2 and 5. It has a role as a volatile oil component and an animal metabolite. It derives from a hydride of a p-xylene.

Aroma threshold values

Detection: 400 ppb

Taste threshold values

Taste characteristics at 10 ppm: musty, chemical, stringent and phenolic.

General Description

Colorless to off-white crystalline solid. Odor threshold concentration 0.4 mg/L. Taste threshold concentration 0.5 mg/L.

Air & Water Reactions

2,5-Dimethylphenol is hygroscopic. Insoluble in water.

Reactivity Profile

2,5-Dimethylphenol is incompatible with bases, acid chlorides, acid anhydrides and oxidizing agents. 2,5-Dimethylphenol corrodes steel, brass, copper and copper alloys.

Health Hazard

Symptoms of exposure to this compound may include severe irritation and burns of the skin and eyes; irritation of the respiratory tract, dizziness, stomach pain, exhaustion, coma and damage to the liver or kidneys. Other symptoms include headache, nausea and vomiting. It may cause corrosion of the tissues of the mucous membranes and upper respiratory tract, eyes and skin. Inhalation may result in burning sensation, coughing, wheezing, laryngitis and shortness of breath. Inhalation may be fatal as a result of spasm, inflammation and edema of the larynx and bronchi; chemical pneumonitis and pulmonary edema. Symptoms of exposure to this class of compounds include skin sensitization, profuse sweating, painless blanching or erythema of the skin, intense thirst, diarrhea, cyanosis from methemoglobinemia, hyperactivity, stupor, blood pressure fall, hyperpnea, abdominal pain, hemolysis and convulsions. If death from respiratory failure is not immediate, jaundice and oliguria or anuria may occur.

Fire Hazard

Flash point data for 2,5-Dimethylphenol are not available. 2,5-Dimethylphenol is probably combustible.

Safety Profile

Poison by ingestion. Moderately toxic by an unspecified route. When heated to decomposition it emits acrid smoke and irritating fumes. Questionable carcinogen with experimental tumorigenic data. Used in disinfectants, solvents, pharmaceuticals, plasticizers, and wetting agents. See also other xylenol entries.

Purification Methods

Crystallise 2,5-xylenol from EtOH/ether. [Beilstein 6 IV 3164.]

2,5-Dimethylphenol Preparation Products And Raw materials

Raw materials

Preparation Products

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2,5-Dimethylphenol Suppliers

Nanjing Datang Chemical Co., Ltd
Tel
25-25-85431992 13951889900
Fax
+86-25-85287178
Email
vip@chemdatang.com
Country
China
ProdList
88
Advantage
66
Powerful Chemical (Shanghai) Co., Ltd.
Tel
021-62211590 18917958225
Fax
021-54339019
Email
pwfchem@163.com
Country
China
ProdList
74
Advantage
58
Changzhou Junchi Chemical Co.,ltd.
Tel
0519-85518211 15195021697
Email
85518211@chemjunchi.com
Country
China
ProdList
62
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12438
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
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View Lastest Price from 2,5-Dimethylphenol manufacturers

Jinan Finer Chemical Co., Ltd
Product
2,5-Dimethylphenol 95-87-4
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%
Supply Ability
500mt/year
Release date
2021-07-16
Hebei Weibang Biotechnology Co., Ltd
Product
2,5-Dimethylphenol 95-87-4
Price
US $10.00-8.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2022-09-29
NANJING PASTEUR ChEMICAL CO.,LTD
Product
2,5-Dimethylphenol 95-87-4
Price
US $0.00-0.00/kg
Min. Order
1000kg
Purity
99.9%
Supply Ability
5000 tons
Release date
2023-11-01

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