ChemicalBook > CAS DataBase List > 6-CHLOROCHROMAN-4-ONE

6-CHLOROCHROMAN-4-ONE

Product Name
6-CHLOROCHROMAN-4-ONE
CAS No.
37674-72-9
Chemical Name
6-CHLOROCHROMAN-4-ONE
Synonyms
6-chloro-2,3-dihydrochroMen-4-one;6-Chloro-4-chrom;BUTTPARK 35\07-32;6-CHLOROCHROMANONE;TIMTEC-BB SBB003732;6-CHLORO-4-CHROMANONE;6-CHLOROCHROMAN-4-ONE;6-Chloro-4-chromanone-1;6-Chloro-4-chroManone 97%;6-Chloro-4-chromanone >
CBNumber
CB2168890
Molecular Formula
C9H7ClO2
Formula Weight
182.6
MOL File
37674-72-9.mol
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6-CHLOROCHROMAN-4-ONE Property

Melting point:
97-102 °C(lit.)
Boiling point:
322.0±42.0 °C(Predicted)
Density 
1.345±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in solvents.
form 
powder to crystal
color 
White to Yellow to Orange
BRN 
124218
InChIKey
LLTDYHFVIVSQPJ-UHFFFAOYSA-N
CAS DataBase Reference
37674-72-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-20/21/22
Safety Statements 
26-36-24/25
WGK Germany 
2
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
640476
Product name
6-Chloro-4-chromanone
Purity
97%
Packaging
1g
Price
$69.3
Updated
2023/06/20
Sigma-Aldrich
Product number
640476
Product name
6-Chloro-4-chromanone
Purity
97%
Packaging
5g
Price
$163
Updated
2023/06/20
TCI Chemical
Product number
C1968
Product name
6-Chloro-4-chromanone
Purity
>98.0%(GC)
Packaging
5g
Price
$81
Updated
2025/07/31
TCI Chemical
Product number
C1968
Product name
6-Chloro-4-chromanone
Purity
>98.0%(GC)
Packaging
25g
Price
$243
Updated
2025/07/31
TRC
Product number
C428873
Product name
6-Chlorochroman-4-one
Packaging
50mg
Price
$60
Updated
2021/12/16
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6-CHLOROCHROMAN-4-ONE Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

6-Chlorochroman-4-one is used as chemical, organic intermediates for pharmaceuticals.

Synthesis

3284-79-5

37674-72-9

General procedure for the synthesis of 6-chlorobenzodihydropyran-4-one from 3-(p-chlorophenoxy)propionic acid: 3-(p-chlorophenoxy)propionic acid (2 g, 10 mmol) was reacted with concentrated sulfuric acid (20 mL) with stirring for 1 hour at room temperature. After completion of the reaction, the mixture was poured into ice water and extracted with ethyl acetate. The organic layer was washed twice with saturated aqueous sodium bicarbonate and subsequently dried with magnesium sulfate. The dried organic phase was filtered and concentrated under reduced pressure. The crude product was purified by solvent recrystallization from ethyl acetate/hexane (1:5) mixture. The resulting crystals were collected by filtration, washed with hexane and dried to give the target product 6-chlorobenzodihydropyran-4-one (1 g, 55% yield): melting point 98-101 °C (literature value: 100-101 °C); 1H NMR (DMSO-d6) δ 2.82 (t, J=6.5 Hz, 2H, 3-H2), 4.56 (t, J=6.5 Hz, 2H, 2 -H2), 7.1 (d, J=8.9 Hz, 1H, 8-H), 7.6 (dd, J=8.9 Hz/2.7 Hz, 1H, 7-H), 7.68 (d, J=2.7 Hz, 1H, 5-H); 13C NMR (DMSO-d6) δ 36.8 (C-3), 66.9 (C-2), 120.3 (C-8) 122.0 (C-4a/C-6), 125.3 (C-5), 135.6 (C-7), 160.1 (C-8a), 190.6 (C-4).

References

[1] Chinese Journal of Chemistry, 2011, vol. 29, # 4, p. 757 - 764
[2] European Journal of Medicinal Chemistry, 2012, vol. 54, p. 834 - 844
[3] Journal of the Indian Chemical Society, 1939, vol. 16, p. 639,644
[4] Journal of the Indian Chemical Society, 1957, vol. 34, p. 467,468
[5] Journal of the American Chemical Society, 1954, vol. 76, p. 5065,5067

6-CHLOROCHROMAN-4-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-CHLOROCHROMAN-4-ONE Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
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View Lastest Price from 6-CHLOROCHROMAN-4-ONE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
6-Chlorochromanone 37674-72-9
Price
US $1.60-6.60/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-19
Shanghai UCHEM Inc.
Product
6-Chloro-4-chromanone 37674-72-9
Price
US $74.00-178.00/g
Min. Order
5g
Purity
0.98
Supply Ability
25kg
Release date
2023-12-07
Shanghai Rlavie Technology Co ltd
Product
6-Chloro-4-chromanone 37674-72-9
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%minHPLC
Supply Ability
100kgs/month
Release date
2021-11-01

37674-72-9, 6-CHLOROCHROMAN-4-ONERelated Search:


  • TIMTEC-BB SBB003732
  • BUTTPARK 35\07-32
  • 4H-1-Benzopyran-4-one, 6-chloro-2,3-dihydro-
  • 6-CHLORO-2,3-DIHYDRO-4H-CHROMEN-4-ONE
  • 6-CHLOROCHROMAN-4-ONE
  • 6-CHLOROCHROMANONE
  • 6-CHLORO-4-CHROMANONE
  • 6-Chloro-4-chromanone (6-Chlorochroman-4-one)
  • 6-Chloro-2,3-dihydro-4H-1-benzopyran-4-one
  • 6-Chloro-3,4-dihydro-2H-1-benzopyran-4-one
  • 6-Chloro-4-chroManone 97%
  • 6-Chloro-4-chrom
  • 6-chloro-2,3-dihydrochroMen-4-one
  • JRH-01803, 6-Chlorochroman-4-one, 97%
  • 6-Chloro-4-chromanone &gt
  • 6-Chloro-4-chromanone-1
  • 37674-72-9
  • C9H7O2Cl
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