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6-CHLOROCHROMAN-4-ONE

Product Name
6-CHLOROCHROMAN-4-ONE
CAS No.
37674-72-9
Chemical Name
6-CHLOROCHROMAN-4-ONE
Synonyms
6-chloro-2,3-dihydrochroMen-4-one;6-Chloro-4-chrom;BUTTPARK 35\07-32;6-CHLOROCHROMANONE;TIMTEC-BB SBB003732;6-CHLORO-4-CHROMANONE;6-CHLOROCHROMAN-4-ONE;6-Chloro-4-chromanone-1;6-Chloro-4-chroManone 97%;6-Chloro-4-chromanone >
CBNumber
CB2168890
Molecular Formula
C9H7ClO2
Formula Weight
182.6
MOL File
37674-72-9.mol
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6-CHLOROCHROMAN-4-ONE Property

Melting point:
97-102 °C(lit.)
Boiling point:
322.0±42.0 °C(Predicted)
Density 
1.345±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in solvents.
form 
powder to crystal
color 
White to Yellow to Orange
BRN 
124218
InChIKey
LLTDYHFVIVSQPJ-UHFFFAOYSA-N
CAS DataBase Reference
37674-72-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-20/21/22
Safety Statements 
26-36-24/25
WGK Germany 
2
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
640476
Product name
6-Chloro-4-chromanone
Purity
97%
Packaging
1g
Price
$69.3
Updated
2023/06/20
Sigma-Aldrich
Product number
640476
Product name
6-Chloro-4-chromanone
Purity
97%
Packaging
5g
Price
$163
Updated
2023/06/20
TCI Chemical
Product number
C1968
Product name
6-Chloro-4-chromanone
Purity
>98.0%(GC)
Packaging
5g
Price
$81
Updated
2025/07/31
TCI Chemical
Product number
C1968
Product name
6-Chloro-4-chromanone
Purity
>98.0%(GC)
Packaging
25g
Price
$243
Updated
2025/07/31
TRC
Product number
C428873
Product name
6-Chlorochroman-4-one
Packaging
10mg
Price
$45
Updated
2021/12/16
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6-CHLOROCHROMAN-4-ONE Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

6-Chlorochroman-4-one is used as chemical, organic intermediates for pharmaceuticals.

Synthesis

3284-79-5

37674-72-9

General procedure for the synthesis of 6-chlorobenzodihydropyran-4-one from 3-(p-chlorophenoxy)propionic acid: 3-(p-chlorophenoxy)propionic acid (2 g, 10 mmol) was reacted with concentrated sulfuric acid (20 mL) with stirring for 1 hour at room temperature. After completion of the reaction, the mixture was poured into ice water and extracted with ethyl acetate. The organic layer was washed twice with saturated aqueous sodium bicarbonate and subsequently dried with magnesium sulfate. The dried organic phase was filtered and concentrated under reduced pressure. The crude product was purified by solvent recrystallization from ethyl acetate/hexane (1:5) mixture. The resulting crystals were collected by filtration, washed with hexane and dried to give the target product 6-chlorobenzodihydropyran-4-one (1 g, 55% yield): melting point 98-101 °C (literature value: 100-101 °C); 1H NMR (DMSO-d6) δ 2.82 (t, J=6.5 Hz, 2H, 3-H2), 4.56 (t, J=6.5 Hz, 2H, 2 -H2), 7.1 (d, J=8.9 Hz, 1H, 8-H), 7.6 (dd, J=8.9 Hz/2.7 Hz, 1H, 7-H), 7.68 (d, J=2.7 Hz, 1H, 5-H); 13C NMR (DMSO-d6) δ 36.8 (C-3), 66.9 (C-2), 120.3 (C-8) 122.0 (C-4a/C-6), 125.3 (C-5), 135.6 (C-7), 160.1 (C-8a), 190.6 (C-4).

References

[1] Chinese Journal of Chemistry, 2011, vol. 29, # 4, p. 757 - 764
[2] European Journal of Medicinal Chemistry, 2012, vol. 54, p. 834 - 844
[3] Journal of the Indian Chemical Society, 1939, vol. 16, p. 639,644
[4] Journal of the Indian Chemical Society, 1957, vol. 34, p. 467,468
[5] Journal of the American Chemical Society, 1954, vol. 76, p. 5065,5067

6-CHLOROCHROMAN-4-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-CHLOROCHROMAN-4-ONE Suppliers

Americas 1 Belgium 1 Canada 1 China 113 Europe 2 France 1 Germany 5 India 34 Japan 2 Switzerland 1 The Netherlands 1 United Kingdom 10 United States 42 Global 214
Alkemi BVBA
Tel
--
Fax
--
Email
nfo@alkemi.be
Country
Belgium
ProdList
2201
Advantage
58
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View Lastest Price from 6-CHLOROCHROMAN-4-ONE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
6-Chlorochromanone 37674-72-9
Price
US $1.60-6.60/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-19
Shanghai UCHEM Inc.
Product
6-Chloro-4-chromanone 37674-72-9
Price
US $74.00-178.00/g
Min. Order
5g
Purity
0.98
Supply Ability
25kg
Release date
2023-12-07
Shanghai Rlavie Technology Co ltd
Product
6-Chloro-4-chromanone 37674-72-9
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%minHPLC
Supply Ability
100kgs/month
Release date
2021-11-01

37674-72-9, 6-CHLOROCHROMAN-4-ONERelated Search:

7-Chloro-4-chromanone 6-Chloro-3-chromanone 8-CHLOROCHROMAN-4-ONE 6-CHLOROCHROMAN-4-ONE 5'-Chloro-2'-hydroxy-3'-nitroacetophenone 6-CHLORO-4'-METHYLFLAVANONE 6-CHLORO-3',4'-DIMETHOXYFLAVANONE (E)-3-BENZYLIDENE-6-CHLOROCHROMAN-4-ONE 6-CHLORO-5-METHYLCHROMANONE ethyl 6-chlorochroman-4-one-2-carboxylate 6,8-DICHLORO-2,3-DIHYDRO-4H-CHROMEN-4-ONE RARECHEM BW GA 0352 (E)-3-(4-METHYLBENZYLIDENE)-6-CHLORO-2,3-DIHYDROCHROMEN-4-ONE (E)-3-(4-FLUOROBENZYLIDENE)-6-CHLORO-2,3-DIHYDROCHROMEN-4-ONE (E)-3-(4-CHLOROBENZYLIDENE)-6-CHLORO-2,3-DIHYDROCHROMEN-4-ONE (E)-3-(4-BROMOBENZYLIDENE)-6-CHLORO-2,3-DIHYDROCHROMEN-4-ONE (E)-3-(4-METHOXYBENZYLIDENE)-6-CHLORO-2,3-DIHYDROCHROMEN-4-ONE BUTTPARK 83\07-45

  • TIMTEC-BB SBB003732
  • BUTTPARK 35\07-32
  • 4H-1-Benzopyran-4-one, 6-chloro-2,3-dihydro-
  • 6-CHLORO-2,3-DIHYDRO-4H-CHROMEN-4-ONE
  • 6-CHLOROCHROMAN-4-ONE
  • 6-CHLOROCHROMANONE
  • 6-CHLORO-4-CHROMANONE
  • 6-Chloro-4-chromanone (6-Chlorochroman-4-one)
  • 6-Chloro-2,3-dihydro-4H-1-benzopyran-4-one
  • 6-Chloro-3,4-dihydro-2H-1-benzopyran-4-one
  • 6-Chloro-4-chroManone 97%
  • 6-Chloro-4-chrom
  • 6-chloro-2,3-dihydrochroMen-4-one
  • JRH-01803, 6-Chlorochroman-4-one, 97%
  • 6-Chloro-4-chromanone &gt
  • 6-Chloro-4-chromanone-1
  • 37674-72-9
  • C9H7O2Cl
  • Building Blocks
  • Benzopyrans
  • KETONE
  • Heterocyclic Building Blocks
  • Benzopyrans
  • BenzopyransHeterocyclic Building Blocks
  • Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks