2-(3-AMINO-PHENYL)-BENZOOXAZOL-5-YLAMINE
- Product Name
- 2-(3-AMINO-PHENYL)-BENZOOXAZOL-5-YLAMINE
- CAS No.
- 13676-47-6
- Chemical Name
- 2-(3-AMINO-PHENYL)-BENZOOXAZOL-5-YLAMINE
- Synonyms
- APBOA;2-(4-AMinophenyl)benzo[d]oxazol-5-aMine;5ABO;AKOS BB-8278;ASISCHEM Y80324;ART-CHEM-BB B025308;TIMTEC-BB SBB009788;2-(4-aminophenyl)-1,3-ben;2-(4-Aminophenyl)benzoxazol-5-amine;2-(4-Aminophenyl)-5-aminobenzoxazole
- CBNumber
- CB2177018
- Molecular Formula
- C13H11N3O
- Formula Weight
- 225.25
- MOL File
- 13676-47-6.mol
2-(3-AMINO-PHENYL)-BENZOOXAZOL-5-YLAMINE Property
- Melting point:
- 231-233°C
- Boiling point:
- 435.2±25.0 °C(Predicted)
- Density
- 1.329
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- solubility
- DMSO, Methanol
- form
- Solid
- pka
- 7.49±0.10(Predicted)
- color
- Off-White to Tan
- λmax
- 310(Heptan) nm
- Sensitive
- Air Sensitive
- InChI
- InChI=1S/C13H11N3O/c14-9-3-1-8(2-4-9)13-16-11-7-10(15)5-6-12(11)17-13/h1-7H,14-15H2
- InChIKey
- UMGYJGHIMRFYSP-UHFFFAOYSA-N
- SMILES
- O1C2=CC=C(N)C=C2N=C1C1=CC=C(N)C=C1
- CAS DataBase Reference
- 13676-47-6
Safety
- HS Code
- 2934.99.4400
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H341Suspected of causing genetic defects
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A3300
- Product name
- 2-(4-Aminophenyl)benzoxazol-5-amine
- Packaging
- 5G
- Price
- $87
- Updated
- 2025/07/31
- Product number
- A3300
- Product name
- 2-(4-Aminophenyl)benzoxazol-5-amine
- Packaging
- 25G
- Price
- $261
- Updated
- 2025/07/31
- Product number
- A581945
- Product name
- 5-Amino-2-(4-aminophenyl)benzoxazole
- Packaging
- 100mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- A581945
- Product name
- 5-Amino-2-(4-aminophenyl)benzoxazole
- Packaging
- 500mg
- Price
- $585
- Updated
- 2021/12/16
- Product number
- A581945
- Product name
- 5-Amino-2-(4-aminophenyl)benzoxazole
- Packaging
- 1g
- Price
- $990
- Updated
- 2021/12/16
2-(3-AMINO-PHENYL)-BENZOOXAZOL-5-YLAMINE Chemical Properties,Usage,Production
Chemical Properties
Off-White to Tan Solid
Uses
2-(3-Amino-phenyl)-benzooxazol-5-ylamine can be used to prepare high-strength flexible transparent polyimide materials.
Application
2-(3-Amino-phenyl)-benzooxazol-5-ylamine is primarily used as an intermediate in organic synthesis, particularly in polymer materials and medicinal chemistry. Specifically, it can be used as a monomer in high-temperature-resistant polymers such as polyimide (PI) to prepare high-performance polymers. Furthermore, its structural properties make it useful as a reagent in biochemical research, enabling the exploration of biological processes.
Synthesis
1037-39-4
13676-47-6
General procedure for the synthesis of 2-(4-aminophenyl)-5-aminobenzo[d]oxazole from 2-(4-nitrophenyl)-5-nitrobenzo[d]oxazole: 2-(4-nitrophenyl)-5-nitrobenzo[d]oxazole (3.22 g, 0.01 mol) was added to a 100 mL single-necked flask followed by the addition of 50 mL of water at room temperature. The pH of the reaction system was adjusted with phosphoric acid to 1. Then, sodium thiosulfate solid (8.5 g, 0.06 mol) was added and the reaction system was warmed up to 100 °C for 16 h. The reaction was completed by adding a solid sodium thiosulfate (8.5 g, 0.06 mol). After completion of the reaction, it was cooled to room temperature and filtered. To the filtrate, 25% by weight of aqueous sodium carbonate was added and neutralized to pH 7. At this point, the product 2-(4-aminophenyl)-5-aminobenzo[d]oxazole was precipitated from the reaction system, and after filtration, several washes, and drying, 2.14 g of the target product was obtained (95% yield, HPLC purity >99.9%).
References
[1] Patent: CN108558770, 2018, A. Location in patent: Paragraph 0082; 0083; 0084
[2] Chemical Biology and Drug Design, 2012, vol. 79, # 6, p. 1018 - 1024
[3] Patent: TWI558696, 2016, B. Location in patent: Paragraph 0035; 0040-0041
2-(3-AMINO-PHENYL)-BENZOOXAZOL-5-YLAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
2-(3-AMINO-PHENYL)-BENZOOXAZOL-5-YLAMINE Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
View Lastest Price from 2-(3-AMINO-PHENYL)-BENZOOXAZOL-5-YLAMINE manufacturers
- Product
- 2-(3-AMINO-PHENYL)-BENZOOXAZOL-5-YLAMINE 13676-47-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-10
- Product
- 2-(3-AMINO-PHENYL)-BENZOOXAZOL-5-YLAMINE 13676-47-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2023-03-09
- Product
- 2-(4-aminophenyl)-1,3-benzoxazol-5-amine 13676-47-6
- Price
- US $5.00-2.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-08-19