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METHIOTHEPIN MALEATE

Product Name
METHIOTHEPIN MALEATE
CAS No.
19728-88-2
Chemical Name
METHIOTHEPIN MALEATE
Synonyms
RO 8-6837;metitepinmaleate;Metitepine maleate;METHIOTHEPIN MALEATE;f)thiepin,10,11-dihydro-8-methylthio-10-(4-methylpiperazino)-dibenzo(hyd;f)thiepin,10,11-dihydro-10-(4-methylpiperazino)-8-methylthio-dibenzo(hyd;1-(10,11-dihydro-8-methylthiodibenzo(b,f)thiepin-10-yl)-4-methyl-piperazin;8-methylthio-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepinmaleate;1-[10,11-DIHYDRO-8-(METHYLTHIO)DIBENZO[B,F]THIEPIN-10-YL]-4-METHYLPIPERAZINE MALEATE;1-Methyl-4-(8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine maleate
CBNumber
CB2181680
Molecular Formula
C24H28N2O4S2
Formula Weight
472.62
MOL File
19728-88-2.mol
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METHIOTHEPIN MALEATE Property

Melting point:
171-173°
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Soluble to 100 mM in DMSO
form 
Powder
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Safety

Toxicity
LD5O in mice (mg/kg): 51 i.v.; 94 orally (Jilek)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H402Harmful to aquatic life

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P311Call a POISON CENTER or doctor/physician.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
23138
Product name
Methiothepin (maleate)
Purity
≥98%
Packaging
10mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
23138
Product name
Methiothepin (maleate)
Purity
≥98%
Packaging
25mg
Price
$70
Updated
2024/03/01
Cayman Chemical
Product number
23138
Product name
Methiothepin (maleate)
Purity
≥98%
Packaging
50mg
Price
$100
Updated
2024/03/01
Cayman Chemical
Product number
23138
Product name
Methiothepin (maleate)
Purity
≥98%
Packaging
100mg
Price
$184
Updated
2024/03/01
TRC
Product number
M260625
Product name
MethiothepinMaleate
Packaging
50mg
Price
$140
Updated
2021/12/16
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METHIOTHEPIN MALEATE Chemical Properties,Usage,Production

Uses

Methiothepin Maleate exhibits anticonvulsant property and it is able to suppress pentylenetetrazol induced fos expression in zebrafish. In addition, Methiothepin Maleate is a 5-HT antagonist.

Uses

Biochemical tool in serotonin receptor binding studies.

Definition

ChEBI: A maleate salt obtained by reaction of methiothepin with one equivalent of maleic acid. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays ffinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively).

METHIOTHEPIN MALEATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHIOTHEPIN MALEATE Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel
86-571-88216897,88216896 13588875226
Fax
86-571-88216895
Email
sales@hzclap.com
Country
CHINA
ProdList
6312
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44806
Advantage
58
Changzhou Furuisi Biotechnology Co., Ltd
Tel
0519-85524369
Email
3477467573@qq.com
Country
China
ProdList
8617
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24644
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58
Jilin Chinese Academy of Sciences-yanshen Technology
Tel
+undefined18143011203
Email
info@chemextension.com
Country
China
ProdList
42056
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58

19728-88-2, METHIOTHEPIN MALEATERelated Search:


  • RO 8-6837
  • 1-(10,11-dihydro-8-methylthiodibenzo(b,f)thiepin-10-yl)-4-methyl-piperazin
  • 8-methylthio-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepinmaleate
  • f)thiepin,10,11-dihydro-10-(4-methylpiperazino)-8-methylthio-dibenzo(hyd
  • f)thiepin,10,11-dihydro-8-methylthio-10-(4-methylpiperazino)-dibenzo(hyd
  • metitepinmaleate
  • Dibenzo(B,F)thiepin, 10,11-dihydro-10-(4-methylpiperazino)-8-methylthio-, hydrogen maleate
  • Dibenzo(B,F)thiepin, 10,11-dihydro-8-methylthio-10-(4-methylpiperazino)-, hydrogen maleate
  • Metitepine maleate
  • Piperazine, 1-(10,11-dihydro-8-methylthiodibenzo(B,F)thiepin-10-yl)-4-methyl-, maleate (1:1)
  • 1-[10,11-DIHYDRO-8-(METHYLTHIO)DIBENZO[B,F]THIEPIN-10-YL]-4-METHYLPIPERAZINE MALEATE
  • METHIOTHEPIN MALEATE
  • Piperazine, 1-[10,11-dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methyl-, (2Z)-2-butenedioate (1:1)
  • 1-Methyl-4-(8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine maleate
  • 19728-88-2