METHIOTHEPIN MALEATE
- Product Name
- METHIOTHEPIN MALEATE
- CAS No.
- 19728-88-2
- Chemical Name
- METHIOTHEPIN MALEATE
- Synonyms
- RO 8-6837;metitepinmaleate;Metitepine maleate;METHIOTHEPIN MALEATE;f)thiepin,10,11-dihydro-8-methylthio-10-(4-methylpiperazino)-dibenzo(hyd;f)thiepin,10,11-dihydro-10-(4-methylpiperazino)-8-methylthio-dibenzo(hyd;1-(10,11-dihydro-8-methylthiodibenzo(b,f)thiepin-10-yl)-4-methyl-piperazin;8-methylthio-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepinmaleate;1-[10,11-DIHYDRO-8-(METHYLTHIO)DIBENZO[B,F]THIEPIN-10-YL]-4-METHYLPIPERAZINE MALEATE;1-Methyl-4-(8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine maleate
- CBNumber
- CB2181680
- Molecular Formula
- C24H28N2O4S2
- Formula Weight
- 472.62
- MOL File
- 19728-88-2.mol
METHIOTHEPIN MALEATE Property
- Melting point:
- 171-173°
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Soluble to 100 mM in DMSO
- form
- Powder
Safety
- Toxicity
- LD5O in mice (mg/kg): 51 i.v.; 94 orally (Jilek)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H402Harmful to aquatic life
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P311Call a POISON CENTER or doctor/physician.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 23138
- Product name
- Methiothepin (maleate)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 23138
- Product name
- Methiothepin (maleate)
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $70
- Updated
- 2024/03/01
- Product number
- 23138
- Product name
- Methiothepin (maleate)
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $100
- Updated
- 2024/03/01
- Product number
- 23138
- Product name
- Methiothepin (maleate)
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $184
- Updated
- 2024/03/01
- Product number
- M260625
- Product name
- MethiothepinMaleate
- Packaging
- 50mg
- Price
- $140
- Updated
- 2021/12/16
METHIOTHEPIN MALEATE Chemical Properties,Usage,Production
Uses
Methiothepin Maleate exhibits anticonvulsant property and it is able to suppress pentylenetetrazol induced fos expression in zebrafish. In addition, Methiothepin Maleate is a 5-HT antagonist.
Uses
Biochemical tool in serotonin receptor binding studies.
Definition
ChEBI: A maleate salt obtained by reaction of methiothepin with one equivalent of maleic acid. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays ffinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively).
METHIOTHEPIN MALEATE Preparation Products And Raw materials
Raw materials
Preparation Products
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