ChemicalBook > CAS DataBase List > Raxibacumab
Raxibacumab
- Product Name
- Raxibacumab
- CAS No.
- 565451-13-0
- Chemical Name
- Raxibacumab
- Synonyms
- Abthrax;Raxibacumab;Research Grade Raxibacumab;Research Grade Raxibacumab (DXX00402)
- CBNumber
- CB21856068
- Formula Weight
- 0
- MOL File
- Mol file
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Raxibacumab Property
- form
- Liquid
- color
- Colorless to light yellow
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Raxibacumab Chemical Properties,Usage,Production
Uses
Treatment of anthrax infection.
brand name
ABthrax (Human Genome Sciences).
in vivo
Raxibacumab (150 μg/kg or 300 μg/kg for i.v., single dose) significantly improved in outcome when it was administered up to 6 h after rats initial exposure to Bacillus anthracis lethal toxin (LeTx) infusion[3].
| Animal Model: | In SD rats after the initiation of a 24-h LeTx infusion[3] |
| Dosage: | 150 μg/kg or 300 μg/kg |
| Administration: | At the time of or 3, 6, 9, or 12 h after the initiation of LeTx infusion, the rats were randomized to be treated i.v. in a single dose |
| Result: | Significantly improved in outcome when it was administered up to 6 h (and approached significance when administered up to 12 h) after initial exposure to LeTx. Rats receiving raxibacumab within 6 hours of toxin administration had a better survival rate than those that received raxibacumab at 9 or 12 hours. |
Raxibacumab Preparation Products And Raw materials
Raw materials
Preparation Products
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