STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1

Product Name: STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1
CAS No.: 142986-44-5
Chemical Name: STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1
Synonyms: PAMAMG1.0;pamam dendrimer, generation 1 solution;STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1;4,7,11,14,18,21-Hexaazatetracosanediamide, 95%;PAMAM dendrimer, ethylenediamine core, generation 1.0 solution;STARBURST (PAMAM) DENDRIMER, GENERATION 1, 20 WT. % SOLUTION IN METHYL ALCOHOL;PAMAM dendrimer, ethylenediamine core, generation 1.0 solution 20 wt. % in methanol;N1,N24-Bis(2-aminoethyl)-4,21-bis[3-[(2-aminoethyl)amino]-3-oxopropyl]-11,14-bis[3-[[2-[bis[3-[(2-aminoethyl)amino]-3-oxopropyl]amino]ethyl]amino]-3-oxopropyl]-8,17-dioxo-4,7,11,14,18,21-hexaazatetracosanediamide;4,7,11,14,18,21-Hexaazatetracosanediamide, N1,N24-bis(2-aminoethyl)-4,21-bis[3-[(2-aminoethyl)amino]-3-oxopropyl]-11,14-bis[3-[[2-[bis[3-[(2-aminoethyl)amino]-3-oxopropyl]amino]ethyl]amino]-3-oxopropyl]-8,17-dioxo-;N1,N24-bis(2-aminoethyl)-4,21-bis[3-[(2-aminoethyl)amino]-3-oxopropyl]-11,14-bis[3-[[2-[bis[3-[(2-aminoethyl)amino]-3-oxopropyl]amino]ethyl]amino]-3-oxopropyl]-8,17-dioxo-4,7,11,14,18,21-hexaazatetracosane diacetamide
CBNumber: CB2187066
Molecular Formula: C62H128N26O12
Formula Weight: 1429.85
MOL File: 142986-44-5.mol

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STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1 Property

Boiling point:: 64.7 °C
Density: 0.82 g/mL at 25 °C
refractive index: n20/D 1.362
Flash point:: 52 °F
storage temp.: 2-8°C
solubility: Water: Soluble
pka: 9.23
form: 20 wt.% in methanol
color: Colorless to light yellow
InChIKey: QVWIZHOFYGKROL-UHFFFAOYSA-N
SMILES: C(NCCN)(=O)CCN(CCC(NCCN)=O)CCNC(=O)CCN(CCC(NCCN(CCC(NCCN)=O)CCC(NCCN)=O)=O)CCN(CCC(NCCN(CCC(NCCN)=O)CCC(NCCN)=O)=O)CCC(=O)NCCN(CCC(NCCN)=O)CCC(NCCN)=O

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Safety

Hazard Codes: F,T
Risk Statements: 11-23/24/25-39/23/24/25-36/37/38
Safety Statements: 7-16-23-45-36/37-26
RIDADR: UN 1230 3/PG 2
WGK Germany: 3
Storage Class: 3 - Flammable liquids
Hazard Classifications: Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Eye Irrit. 2
Flam. Liq. 2
Skin Irrit. 2
STOT SE 1
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 412384
Product name: PAMAM dendrimer, ethylenediamine core, generation 1.0 solution
Purity: 20 wt. % in methanol
Packaging: 5g
Price: $679
Updated: 2025/07/31

Sigma-Aldrich

Product number: 412384
Product name: PAMAM dendrimer, ethylenediamine core, generation 1.0 solution
Purity: 20 wt. % in methanol
Packaging: 25g
Price: $2470
Updated: 2025/07/31

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STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1 Chemical Properties,Usage,Production

Uses

Starburst 1st Generation (PAMAM G1.0) is a Polyamidoamine (HY-164657; PAMAM) dendrimer with amine termini that has been used as a drug delivery system in vitro. Starburst 1st Generation conjugated to di-n-dodecylamine and encapsulating 5-Fluorouracil (HY-90006) increase the solubility of 5-Fluorouracil and are cytotoxic to AGS gastric adenocarcinoma cells[1].

References

[1] Ender Sarigul, et al. Polyamidoamine Dendron-Bearing Lipids as Drug-Delivery Excipients. Molecules. 2022 Nov 13;27(22):7817. DOI:10.3390/molecules27227817
[2] TISHA C. KING HEIDEN . Developmental toxicity of low generation PAMAM dendrimers in zebrafish[J]. Toxicology and applied pharmacology, 2007, 225 1: Pages 70-79. DOI: 10.1016/j.taap.2007.07.009
[3] XIAOYE ZHANG. Preparation of PVDF/Hyperbranched-Nano-Palygorskite Composite Membrane for Efficient Removal of Heavy Metal Ions.[J]. Polymers, 2019, 11 1. DOI: 10.3390/polym11010156

STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1 Suppliers

China 32 Switzerland 1 United States 2 Global 35

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142986-44-5, STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1Related Search:

3,3'-BIS(METHYLAMINO)-N-METHYLDIPROPYLAMINE N,N'-Bis(2-aminoethyl)-1,3-propanediamine STARBURST(R) (PAMAM) DENDRIMER, GENERATION O METHYLIMINOBISPROPIONAMIDE STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1.5 STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1 N,N'-BIS(3-AMINOPROPYL)ETHYLENEDIAMINE

PAMAM dendrimer, ethylenediamine core, generation 1.0 solution 20 wt. % in methanol

STARBURST (PAMAM) DENDRIMER, GENERATION 1, 20 WT. % SOLUTION IN METHYL ALCOHOL

pamam dendrimer, generation 1 solution

PAMAM dendrimer, ethylenediamine core, generation 1.0 solution

4,7,11,14,18,21-Hexaazatetracosanediamide, 95%

STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1

4,7,11,14,18,21-Hexaazatetracosanediamide, N1,N24-bis(2-aminoethyl)-4,21-bis[3-[(2-aminoethyl)amino]-3-oxopropyl]-11,14-bis[3-[[2-[bis[3-[(2-aminoethyl)amino]-3-oxopropyl]amino]ethyl]amino]-3-oxopropyl]-8,17-dioxo-

PAMAMG1.0

N1,N24-Bis(2-aminoethyl)-4,21-bis[3-[(2-aminoethyl)amino]-3-oxopropyl]-11,14-bis[3-[[2-[bis[3-[(2-aminoethyl)amino]-3-oxopropyl]amino]ethyl]amino]-3-oxopropyl]-8,17-dioxo-4,7,11,14,18,21-hexaazatetracosanediamide

N1,N24-bis(2-aminoethyl)-4,21-bis[3-[(2-aminoethyl)amino]-3-oxopropyl]-11,14-bis[3-[[2-[bis[3-[(2-aminoethyl)amino]-3-oxopropyl]amino]ethyl]amino]-3-oxopropyl]-8,17-dioxo-4,7,11,14,18,21-hexaazatetracosane diacetamide

142986-44-5

NH2CH22NH2G1dendriPAMAMNH28

C62H128N26O12

Amino Surface Groups

Dendrimers

PAMAM Dendrimers