STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1
- Product Name
- STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1
- CAS No.
- 142986-44-5
- Chemical Name
- STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1
- Synonyms
- PAMAMG1.0;pamam dendrimer, generation 1 solution;STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1;4,7,11,14,18,21-Hexaazatetracosanediamide, 95%;PAMAM dendrimer, ethylenediamine core, generation 1.0 solution;STARBURST (PAMAM) DENDRIMER, GENERATION 1, 20 WT. % SOLUTION IN METHYL ALCOHOL;PAMAM dendrimer, ethylenediamine core, generation 1.0 solution 20 wt. % in methanol;N1,N24-Bis(2-aminoethyl)-4,21-bis[3-[(2-aminoethyl)amino]-3-oxopropyl]-11,14-bis[3-[[2-[bis[3-[(2-aminoethyl)amino]-3-oxopropyl]amino]ethyl]amino]-3-oxopropyl]-8,17-dioxo-4,7,11,14,18,21-hexaazatetracosanediamide;4,7,11,14,18,21-Hexaazatetracosanediamide, N1,N24-bis(2-aminoethyl)-4,21-bis[3-[(2-aminoethyl)amino]-3-oxopropyl]-11,14-bis[3-[[2-[bis[3-[(2-aminoethyl)amino]-3-oxopropyl]amino]ethyl]amino]-3-oxopropyl]-8,17-dioxo-
- CBNumber
- CB2187066
- Molecular Formula
- C62H128N26O12
- Formula Weight
- 1429.85
- MOL File
- 142986-44-5.mol
STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1 Property
- Boiling point:
- 64.7 °C
- Density
- 0.82 g/mL at 25 °C
- refractive index
- n20/D 1.362
- Flash point:
- 52 °F
- storage temp.
- 2-8°C
- solubility
- Water: Soluble
- form
- 20 wt.% in methanol
- color
- Colorless to light yellow
- InChIKey
- QVWIZHOFYGKROL-UHFFFAOYSA-N
- SMILES
- C(NCCN)(=O)CCN(CCC(NCCN)=O)CCNC(=O)CCN(CCC(NCCN(CCC(NCCN)=O)CCC(NCCN)=O)=O)CCN(CCC(NCCN(CCC(NCCN)=O)CCC(NCCN)=O)=O)CCC(=O)NCCN(CCC(NCCN)=O)CCC(NCCN)=O
Safety
- Hazard Codes
- F,T
- Risk Statements
- 11-23/24/25-39/23/24/25-36/37/38
- Safety Statements
- 7-16-23-45-36/37-26
- RIDADR
- UN 1230 3/PG 2
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H370Causes damage to organs
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 412384
- Product name
- PAMAM dendrimer, ethylenediamine core, generation 1.0 solution
- Purity
- 20 wt. % in methanol
- Packaging
- 5g
- Price
- $679
- Updated
- 2025/07/31
- Product number
- 412384
- Product name
- PAMAM dendrimer, ethylenediamine core, generation 1.0 solution
- Purity
- 20 wt. % in methanol
- Packaging
- 25g
- Price
- $2470
- Updated
- 2025/07/31
STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1 Chemical Properties,Usage,Production
Uses
Starburst 1st Generation (PAMAM G1.0) is a Polyamidoamine (HY-164657; PAMAM) dendrimer with amine termini that has been used as a drug delivery system in vitro. Starburst 1st Generation conjugated to di-n-dodecylamine and encapsulating 5-Fluorouracil (HY-90006) increase the solubility of 5-Fluorouracil and are cytotoxic to AGS gastric adenocarcinoma cells[1].
References
[1] Ender Sarigul, et al. Polyamidoamine Dendron-Bearing Lipids as Drug-Delivery Excipients. Molecules. 2022 Nov 13;27(22):7817. DOI:10.3390/molecules27227817
[2] TISHA C. KING HEIDEN . Developmental toxicity of low generation PAMAM dendrimers in zebrafish[J]. Toxicology and applied pharmacology, 2007, 225 1: Pages 70-79. DOI: 10.1016/j.taap.2007.07.009
[3] XIAOYE ZHANG. Preparation of PVDF/Hyperbranched-Nano-Palygorskite Composite Membrane for Efficient Removal of Heavy Metal Ions.[J]. Polymers, 2019, 11 1. DOI: 10.3390/polym11010156
STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1 Preparation Products And Raw materials
Raw materials
Preparation Products
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