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STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1

Product Name
STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1
CAS No.
142986-44-5
Chemical Name
STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1
Synonyms
PAMAMG1.0;pamam dendrimer, generation 1 solution;STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1;4,7,11,14,18,21-Hexaazatetracosanediamide, 95%;PAMAM dendrimer, ethylenediamine core, generation 1.0 solution;STARBURST (PAMAM) DENDRIMER, GENERATION 1, 20 WT. % SOLUTION IN METHYL ALCOHOL;PAMAM dendrimer, ethylenediamine core, generation 1.0 solution 20 wt. % in methanol;N1,N24-Bis(2-aminoethyl)-4,21-bis[3-[(2-aminoethyl)amino]-3-oxopropyl]-11,14-bis[3-[[2-[bis[3-[(2-aminoethyl)amino]-3-oxopropyl]amino]ethyl]amino]-3-oxopropyl]-8,17-dioxo-4,7,11,14,18,21-hexaazatetracosanediamide;4,7,11,14,18,21-Hexaazatetracosanediamide, N1,N24-bis(2-aminoethyl)-4,21-bis[3-[(2-aminoethyl)amino]-3-oxopropyl]-11,14-bis[3-[[2-[bis[3-[(2-aminoethyl)amino]-3-oxopropyl]amino]ethyl]amino]-3-oxopropyl]-8,17-dioxo-
CBNumber
CB2187066
Molecular Formula
C62H128N26O12
Formula Weight
1429.85
MOL File
142986-44-5.mol
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STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1 Property

Boiling point:
64.7 °C
Density 
0.82 g/mL at 25 °C
refractive index 
n20/D 1.362
Flash point:
52 °F
storage temp. 
2-8°C
solubility 
Water: Soluble
form 
20 wt.% in methanol
color 
Colorless to light yellow
InChIKey
QVWIZHOFYGKROL-UHFFFAOYSA-N
SMILES
C(NCCN)(=O)CCN(CCC(NCCN)=O)CCNC(=O)CCN(CCC(NCCN(CCC(NCCN)=O)CCC(NCCN)=O)=O)CCN(CCC(NCCN(CCC(NCCN)=O)CCC(NCCN)=O)=O)CCC(=O)NCCN(CCC(NCCN)=O)CCC(NCCN)=O
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Safety

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25-36/37/38
Safety Statements 
7-16-23-45-36/37-26
RIDADR 
UN 1230 3/PG 2
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
412384
Product name
PAMAM dendrimer, ethylenediamine core, generation 1.0 solution
Purity
20 wt. % in methanol
Packaging
5g
Price
$679
Updated
2025/07/31
Sigma-Aldrich
Product number
412384
Product name
PAMAM dendrimer, ethylenediamine core, generation 1.0 solution
Purity
20 wt. % in methanol
Packaging
25g
Price
$2470
Updated
2025/07/31
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STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1 Chemical Properties,Usage,Production

Uses

Starburst 1st Generation (PAMAM G1.0) is a Polyamidoamine (HY-164657; PAMAM) dendrimer with amine termini that has been used as a drug delivery system in vitro. Starburst 1st Generation conjugated to di-n-dodecylamine and encapsulating 5-Fluorouracil (HY-90006) increase the solubility of 5-Fluorouracil and are cytotoxic to AGS gastric adenocarcinoma cells[1].

References

[1] Ender Sarigul, et al. Polyamidoamine Dendron-Bearing Lipids as Drug-Delivery Excipients. Molecules. 2022 Nov 13;27(22):7817. DOI:10.3390/molecules27227817
[2] TISHA C. KING HEIDEN . Developmental toxicity of low generation PAMAM dendrimers in zebrafish[J]. Toxicology and applied pharmacology, 2007, 225 1: Pages 70-79. DOI: 10.1016/j.taap.2007.07.009
[3] XIAOYE ZHANG. Preparation of PVDF/Hyperbranched-Nano-Palygorskite Composite Membrane for Efficient Removal of Heavy Metal Ions.[J]. Polymers, 2019, 11 1. DOI: 10.3390/polym11010156

STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1 Suppliers

China 32 Switzerland 1 United States 2 Global 35
SIGMA-RBI
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Switzerland
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142986-44-5, STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1Related Search:

3,3'-BIS(METHYLAMINO)-N-METHYLDIPROPYLAMINE N,N'-Bis(2-aminoethyl)-1,3-propanediamine STARBURST(R) (PAMAM) DENDRIMER, GENERATION O METHYLIMINOBISPROPIONAMIDE STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1.5 STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1 N,N'-BIS(3-AMINOPROPYL)ETHYLENEDIAMINE

  • PAMAM dendrimer, ethylenediamine core, generation 1.0 solution 20 wt. % in methanol
  • STARBURST (PAMAM) DENDRIMER, GENERATION 1, 20 WT. % SOLUTION IN METHYL ALCOHOL
  • pamam dendrimer, generation 1 solution
  • PAMAM dendrimer, ethylenediamine core, generation 1.0 solution
  • 4,7,11,14,18,21-Hexaazatetracosanediamide, 95%
  • STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1
  • 4,7,11,14,18,21-Hexaazatetracosanediamide, N1,N24-bis(2-aminoethyl)-4,21-bis[3-[(2-aminoethyl)amino]-3-oxopropyl]-11,14-bis[3-[[2-[bis[3-[(2-aminoethyl)amino]-3-oxopropyl]amino]ethyl]amino]-3-oxopropyl]-8,17-dioxo-
  • PAMAMG1.0
  • N1,N24-Bis(2-aminoethyl)-4,21-bis[3-[(2-aminoethyl)amino]-3-oxopropyl]-11,14-bis[3-[[2-[bis[3-[(2-aminoethyl)amino]-3-oxopropyl]amino]ethyl]amino]-3-oxopropyl]-8,17-dioxo-4,7,11,14,18,21-hexaazatetracosanediamide
  • 142986-44-5
  • NH2CH22NH2G1dendriPAMAMNH28
  • C62H128N26O12
  • Amino Surface Groups
  • Dendrimers
  • PAMAM Dendrimers