CLOFOCTOL

Product Name: CLOFOCTOL
CAS No.: 37693-01-9
Chemical Name: CLOFOCTOL
Synonyms: Octofene;Gramplus;CLOFOCTOL;2-[2,4-DICHLOROBENZYL]-4-[1,1,3,3-TETRAMETHYLBUTYL]PHENOL;α-[2,4-Dichlorophenyl]-4-[1,1,3,3-tetramethylbutyl]-o-cresol;2-((2,4-dichlorophenyl)methyl)-4-(1,1,3,3-tetramethylbutyl)phenol;2-((2,4-dichlorophenyl)methyl)-4-(1,1,3,3-tetramethylbutyl)-pheno;2-[(2,4-dichlorophenyl)methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol;Phenol, 2-[(2,4-dichlorophenyl)methyl]-4-(1,1,3,3-tetramethylbutyl)-;anticancer,antibacterial,Inhibitor,Antibiotic,prostate cancer,Clofoctol,Bacterial,inhibit,SARS-CoV,SARS coronavirus,antiviral
CBNumber: CB2197054
Molecular Formula: C21H26Cl2O
Formula Weight: 365.34
MOL File: 37693-01-9.mol

More

Less

CLOFOCTOL Property

Melting point:: 78°
Boiling point:: 447.7±40.0 °C(Predicted)
Density: 1.127±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO:100.0(Max Conc. mg/mL);273.72(Max Conc. mM)
form: Solid
pka: 10.09±0.45(Predicted)
color: White to off-white

More

Less

Safety

WGK Germany: 2
RTECS: SL0533000
Toxicity: LD50 orally in male rats: >4 g/kg (Debat)

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: C586943
Product name: Clofoctol
Packaging: 1g
Price: $40
Updated: 2021/12/16

TRC

Product number: C586943
Product name: Clofoctol
Packaging: 2.5g
Price: $85
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0016253
Product name: CLOFOCTOL
Purity: 95.00%
Packaging: 5MG
Price: $501.18
Updated: 2021/12/16

ChemScene

Product number: CS-4755
Product name: Clofoctol
Purity: 99.93%
Packaging: 100mg
Price: $60
Updated: 2021/12/16

Crysdot

Product number: CD31002050
Product name: Clofoctol
Purity: 98+%
Packaging: 100mg
Price: $50
Updated: 2021/12/16

More

Less

CLOFOCTOL Chemical Properties,Usage,Production

Originator

Octofene,Debat,France,1978

Uses

antibacterial

Uses

Clofoctol is a bacteriostatic antibiotic used against gram-positive bacteria.

Definition

ChEBI: 2-[(2,4-dichlorophenyl)methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol is a diarylmethane.

Manufacturing Process

The following were introduced into a 1 liter flask provided with a reflux condenser: 206 g (1 mol) of p-(1,1,3,3-tetramethylbutyl)-phenol, 147 g (0.75 mol) of 2,4-dichlorobenzyl chloride, 27 g (0.2 mol) of pure melted zinc chloride, and 750 ml of anhydrous chloroform.
The mixture was heated to reflux for 24 hours. The chloroformic reaction mixture was washed with water, and then dried over anhydrous sodium sulfate. The chloroform was evaporated off and the oil obtained was fractionally distilled under a pressure of 0.2 mm Hg. The fraction distilling at 140°C to 160°C, being the desired product indicated above, was collected and crystallized. Yield: 94 g (32% of theory); MP 78°C (after recrystallization in petroleum ether).

Therapeutic Function

Antiinfective, Bacteriostatic

CLOFOCTOL Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

CLOFOCTOL Suppliers

China 37 France 1 Switzerland 1 United Kingdom 1 United States 11 Global 51

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3866
Advantage: 58

Shanghai Rechem science Co., Ltd.

Tel: 21-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2987
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

Aikon International Limited

Tel: 025-66113011 13155353615
Fax: (7)02557626880
Email: qzhang@aikonchem.com
Country: China
ProdList: 15394
Advantage: 58

Shanghai Han-Xiang Chemical Co., Ltd.

Tel: 15971444841
Fax: 18327183813
Email: amber@biochempartner.com
Country: China
ProdList: 3061
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

37693-01-9, CLOFOCTOLRelated Search:

Clomifene 4-tert-Octylphenol CLOFOCTOL 2-METHYL-4-TERT-OCTYLPHENOL

CLOFOCTOL

2-[2,4-DICHLOROBENZYL]-4-[1,1,3,3-TETRAMETHYLBUTYL]PHENOL

2-((2,4-dichlorophenyl)methyl)-4-(1,1,3,3-tetramethylbutyl)-pheno

2-((2,4-dichlorophenyl)methyl)-4-(1,1,3,3-tetramethylbutyl)phenol

α-[2,4-Dichlorophenyl]-4-[1,1,3,3-tetramethylbutyl]-o-cresol

Gramplus

Octofene

2-[(2,4-dichlorophenyl)methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol

Phenol, 2-[(2,4-dichlorophenyl)methyl]-4-(1,1,3,3-tetramethylbutyl)-

anticancer,antibacterial,Inhibitor,Antibiotic,prostate cancer,Clofoctol,Bacterial,inhibit,SARS-CoV,SARS coronavirus,antiviral

37693-01-9

C21H26Cl2O

Analytical Standards

Analytical Chromatography Product Catalog

Alphabetic

CI - CL

OCTOPHENE